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MX2015013109A - Compuestos y matrices para su uso en el crecimiento y la reparación de los huesos. - Google Patents

Compuestos y matrices para su uso en el crecimiento y la reparación de los huesos.

Info

Publication number
MX2015013109A
MX2015013109A MX2015013109A MX2015013109A MX2015013109A MX 2015013109 A MX2015013109 A MX 2015013109A MX 2015013109 A MX2015013109 A MX 2015013109A MX 2015013109 A MX2015013109 A MX 2015013109A MX 2015013109 A MX2015013109 A MX 2015013109A
Authority
MX
Mexico
Prior art keywords
cells
matrices
compounds
matrix
repair
Prior art date
Application number
MX2015013109A
Other languages
English (en)
Other versions
MX381471B (es
Inventor
John R Cashman
Daniel R Ryan
Sigeng Chen
Original Assignee
Human Biomolecular Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Biomolecular Res Inst filed Critical Human Biomolecular Res Inst
Publication of MX2015013109A publication Critical patent/MX2015013109A/es
Publication of MX381471B publication Critical patent/MX381471B/es

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    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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Abstract

Se describieron composiciones de moléculas de bajo peso molecular, matrices y células aisladas incluidos los métodos de preparación y métodos para la diferenciación, transdiferenciación y proliferación de células animales como el linaje de células osteoblasticas. Los ejemplos de materiales osteogénicos que se administraron a células o se cocultivaron con células están representados por compuestos de Formula II, IV y VI independiente o preferentemente combinados con una matriz para obtener células óseas. También se combinaron células estimuladas por moléculas de bajo peso molecular con una matriz, se mezclaron con un adhesivo celular o material portador y se implantaron en un sitio en un animal para la reparación de huesos. También se utilizaron matrices pretratadas con compuestos de Formula II, IV y VI para hacer que las células migraran a la matriz que es útil con fines terapéuticos.
MX2015013109A 2013-03-15 2014-03-17 Compuestos y matrices para su uso en el crecimiento y la reparación de los huesos. MX381471B (es)

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US20210138117A1 (en) 2021-05-13
CA3131352A1 (en) 2014-09-18
EP3038621B1 (en) 2020-12-02
MX2021003649A (es) 2021-08-05
US10874766B2 (en) 2020-12-29
US20160038641A1 (en) 2016-02-11
SG10201710796PA (en) 2018-02-27
AU2014232275A1 (en) 2015-10-08
CA2906938A1 (en) 2014-09-18
MX381471B (es) 2025-03-12
US11596716B2 (en) 2023-03-07
EP3038621A2 (en) 2016-07-06
EP3038621A4 (en) 2017-08-09
JP6901792B2 (ja) 2021-07-14
WO2014146039A3 (en) 2014-12-18
CA2906938C (en) 2021-11-16
AU2022206722A1 (en) 2022-09-01
WO2014146039A2 (en) 2014-09-18
AU2021202481A1 (en) 2021-05-20
HUE052928T2 (hu) 2021-05-28
AU2019203101A1 (en) 2019-05-23
JP6577452B2 (ja) 2019-09-18
SG11201507629XA (en) 2015-10-29
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