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MX2015003968A - Angiotensina en el tratamiento de condiciones cerebrales. - Google Patents

Angiotensina en el tratamiento de condiciones cerebrales.

Info

Publication number
MX2015003968A
MX2015003968A MX2015003968A MX2015003968A MX2015003968A MX 2015003968 A MX2015003968 A MX 2015003968A MX 2015003968 A MX2015003968 A MX 2015003968A MX 2015003968 A MX2015003968 A MX 2015003968A MX 2015003968 A MX2015003968 A MX 2015003968A
Authority
MX
Mexico
Prior art keywords
angiotensin
treating brain
brain conditions
conditions
methods
Prior art date
Application number
MX2015003968A
Other languages
English (en)
Other versions
MX366134B (es
Inventor
Richard Franklin
Original Assignee
Tarix Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tarix Pharmaceuticals Ltd filed Critical Tarix Pharmaceuticals Ltd
Publication of MX2015003968A publication Critical patent/MX2015003968A/es
Publication of MX366134B publication Critical patent/MX366134B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/085—Angiotensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Hematology (AREA)
  • Zoology (AREA)

Abstract

La presente invención proporciona, entre otras cosas, métodos y composiciones para tratar condiciones cerebrales. En algunas modalidades, los métodos incluyen administrar a un sujeto que sufre de o es susceptible a una condición cerebral un péptido de angiotensina (1-7) por vía de una ruta de administración ya sea intravenosa o subcutánea.
MX2015003968A 2012-10-02 2013-10-02 Angiotensina en el tratamiento de condiciones cerebrales. MX366134B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261708793P 2012-10-02 2012-10-02
US201261720299P 2012-10-30 2012-10-30
PCT/US2013/062969 WO2014055591A1 (en) 2012-10-02 2013-10-02 Angiotensin in treating brain conditions

Publications (2)

Publication Number Publication Date
MX2015003968A true MX2015003968A (es) 2016-02-05
MX366134B MX366134B (es) 2019-06-28

Family

ID=49919223

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015003968A MX366134B (es) 2012-10-02 2013-10-02 Angiotensina en el tratamiento de condiciones cerebrales.

Country Status (11)

Country Link
US (4) US8633158B1 (es)
EP (1) EP2903605B1 (es)
JP (2) JP6302916B2 (es)
KR (1) KR20150067228A (es)
CN (1) CN104837485A (es)
AU (2) AU2013327453A1 (es)
CA (1) CA2885912A1 (es)
ES (1) ES2689781T3 (es)
MX (1) MX366134B (es)
RU (2) RU2661109C2 (es)
WO (1) WO2014055591A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8633158B1 (en) 2012-10-02 2014-01-21 Tarix Pharmaceuticals Ltd. Angiotensin in treating brain conditions
CA2916701A1 (en) * 2013-07-03 2015-01-08 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method for treating cognitive dysfunction
US9333233B2 (en) * 2014-02-25 2016-05-10 Tarix Pharmaceuticals Ltd. Methods and compositions for the delayed treatment of stroke
WO2016010844A1 (en) * 2014-07-14 2016-01-21 Tarix Pharmaceuticals Ltd Methods and compositions for the treatment of stroke
EP3171886A4 (en) * 2014-07-21 2018-01-24 The Arizona Board of Regents On Behalf of the University of Arizona Ang-(1-7) derviative oligopeptides and methods for using and producing the same
US10183055B2 (en) 2014-07-21 2019-01-22 Arizona Board Of Regents On Behalf Of The University Of Arizona Ang-(1-7) derivative oligopeptides for the treatment of pain and other indications
CN106699844B (zh) * 2015-07-13 2020-07-03 首都医科大学 The-RGDVGRPAK十肽，其制备，活性及应用
CN106699843B (zh) * 2015-07-13 2020-07-28 首都医科大学 RGDVGRPAK-The十肽，其制备，活性及应用
US20180200326A1 (en) * 2017-01-09 2018-07-19 Arizona Board Of Regents On Behalf Of The University Of Arizona Ang-(1-7) and derivative oligopeptides for the treatment of traumatic brain injury and other cognitive impairments
CN109553658B (zh) * 2018-12-13 2022-10-04 重庆大学 Ang-(1-7)的氮杂多肽类似物、制备方法及应用

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4244946A (en) 1979-06-11 1981-01-13 The Salk Institute For Biological Studies Water-soluble peptides affecting gonadal function
US4305872A (en) 1979-10-19 1981-12-15 Kenneth Wingrove Polypeptide derivatives
US4316891A (en) 1980-06-14 1982-02-23 The Salk Institute For Biological Studies Extended N-terminal somatostatin
SU1067796A1 (ru) 1981-10-30 1986-01-15 Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвсср Циклический аналог ангиотензина,обладающий способностью ингибировать прессорное и миотропное действие ангиотензина
JPH09502977A (ja) 1993-09-24 1997-03-25 ザ ユニバーシティ オブ サザーン カリフォルニア 組織修復におけるアンギオテンシン▲ｉｉｉ▼およびその類似体の使用
US5955430A (en) 1993-09-24 1999-09-21 University Of Southern California Use of angiotensin II fragments and analogs thereof in tissue repair
DE69435301D1 (de) 1993-09-24 2010-08-26 Univ Southern California Verwendung von Angiotensin-II-Analogen zur Gewebewiederherstellung
US5834432A (en) 1995-06-06 1998-11-10 The University Of Southern California Use of angiotensin II Type 2 receptor agonists in tissue repair
AU722985B2 (en) 1996-07-12 2000-08-17 Mcgill University Compounds and methods for modulating cell adhesion
US20020168761A1 (en) 2000-01-24 2002-11-14 Gour Barbara J. Peptidomimetic modulators of cell adhesion
US6110895A (en) 1996-12-16 2000-08-29 University Of Southern California Method of promoting healing in skin grafts
US6335195B1 (en) 1997-01-28 2002-01-01 Maret Corporation Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
US5917151A (en) 1997-08-29 1999-06-29 Ut Automotive Dearborn, Inc. Multi-shot molds for manufacturing wire harnesses
SG92610A1 (en) 1997-10-24 2002-11-19 Univ Singapore The use of des-aspartate-angiotensin i as an agent for the treatment and prevention of neointima formation, restenosis, and arteriosclerosis
EP1047441A1 (en) 1997-11-26 2000-11-02 University Of Southern California Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
US6248587B1 (en) 1997-11-26 2001-06-19 University Of Southern Cailfornia Method for promoting mesenchymal stem and lineage-specific cell proliferation
CA2319701C (en) 1998-02-09 2009-09-29 University Of Southern California Method of promoting erythropoiesis
US7173011B2 (en) 2000-11-20 2007-02-06 University Of Southern California Radiation therapy methods
US6455500B1 (en) 1998-03-10 2002-09-24 University Of Southern California Radiation therapy methods
CA2659664C (en) 1998-03-10 2013-05-07 University Of Southern California Improved radiation therapy methods
AU3077299A (en) 1998-03-11 1999-09-27 University Of Southern California Method of promoting production of living tissue equivalents
CA2324988A1 (en) 1998-04-09 1999-10-21 University Of Southern California Methods for treatment and prevention of infections
US6762167B1 (en) 1998-05-11 2004-07-13 University Of Southern California Methods for treating a patient undergoing chemotherapy
EP1073453B1 (en) 1998-05-11 2005-04-13 University Of Southern California Use of angiotensin analogs for the manufacture of a medicament for increasing white blood cell survival and mobilizing haematopoietic progenitor cells following chemotherapy
US6916783B2 (en) 1998-07-13 2005-07-12 University Of Southern California Methods for accelerating bone and cartilage growth and repair
JP3686335B2 (ja) 1998-07-13 2005-08-24 ユニヴァースティ オブ サザーン カリフォルニア 骨および軟骨成長と修復を促進する方法
CA2339330A1 (en) 1998-08-13 2000-02-24 University Of Southern California Methods to increase blood flow to ischemic tissue
CA2367107C (en) 1999-03-23 2003-10-14 University Of Southern California Methods for limiting scar and adhesion formation
US6730775B1 (en) 1999-03-23 2004-05-04 University Of Southern California Methods for limiting scar and adhesion formation
YU78601A (sh) 1999-05-05 2005-07-19 Aventis Pharma Deutschland Gmbh. 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže
US7338938B2 (en) 1999-05-10 2008-03-04 University Of Southern California Methods for treating a patient undergoing chemotherapy
US6821953B1 (en) 1999-12-16 2004-11-23 University Of Southern California Methods for treating and preventing damage to mucosal tissue
WO2001044270A2 (en) 1999-12-16 2001-06-21 University Of Southern California Methods for treating and preventing diabetic complications by use of angiotensin-related peptides
DE60017793T2 (de) 1999-12-16 2006-01-05 University Of Southern California, Los Angeles Verfahren zur vorbeugung und behandlung von beschädigungen des schleimhautgewebes
WO2001098325A1 (en) 2000-06-19 2001-12-27 University Of Southern California Methods for treating and preventing alopecia
US6747008B1 (en) 2000-06-19 2004-06-08 University Of Southern California Methods for treating and preventing alopecia
AU2002308522A1 (en) 2001-05-01 2002-11-11 University Of Southern California Methods for inhibiting tumor cell proliferation
BRPI0105509B8 (pt) 2001-11-05 2021-05-25 Univ Minas Gerais formulações do peptídeo angiotensina-(1-7) usando as ciclodextrinas, lipossomas e o polímero plga
CA2467095A1 (en) 2001-11-23 2003-05-30 Solvay Pharmaceuticals Gmbh Hypertonia treatment during the acute phase of a cerebrovascular accident
DE10306179A1 (de) * 2003-02-13 2004-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe
BRPI0502497A (pt) * 2005-06-28 2007-02-06 Univ Minas Gerais uso de agonistas e antagonistas do receptor acoplado a proteìna g, mas, como moduladores de atividade apoptótica para o estudo, a prevenção e o tratamento de doenças
BRPI0602366B1 (pt) 2006-04-26 2017-12-12 Universidade Federal De Minas Gerais Use of agonists of the receptor coupled to protein g, but, in the treatment of metabolic syndrome, its components and their complications
WO2008130217A1 (en) * 2006-08-08 2008-10-30 Applied Nanosystems B.V. Cyclic angiotensin analogs
AT506258A1 (de) 2007-12-18 2009-07-15 Apeiron Biolog Forschungs Und Behandlung inflammatorischer krankheiten
EP2077119A1 (de) 2007-12-21 2009-07-08 Apeiron Biologics Forschungs- und Entwicklungsgesellschaft M.B.H. Behandlung von Fibrosen und Lebererkrankungen
BRPI0800585B8 (pt) * 2008-02-13 2021-05-25 Univ Minas Gerais composições farmacêuticas do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7) e uso do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7)
WO2009114461A2 (en) 2008-03-10 2009-09-17 University Of Southern California Angiotensin (1-7) dosage forms and uses thereof
AT506632A1 (de) 2008-04-09 2009-10-15 Apeiron Biolog Forschungs Und Behandlung von tumorerkrankungen
EP2163259B1 (en) 2008-09-12 2012-06-13 Charité-Universitätsmedizin Berlin (Charité) Use of an Ang-(1-7) receptor agonist in acute lung injury
CL2008003736A1 (es) 2008-12-15 2009-05-29 Univ Pontificia Catolica Chile Uso de angiotensina (1-9) para preparar un medicamento, util para prevenir, revertir y/o disminuir el remodelado cardiovascular, pulmonar, renal y/o cerebral.
EP2398493A1 (en) 2009-02-17 2011-12-28 Sygnis Bioscience GmbH & Co. KG Use of g-csf for the extension of the therapeutic time-window of thrombolytic stroke therapy
EP2455388A1 (en) * 2010-11-23 2012-05-23 LanthioPep B.V. Novel angiotensin type 2 (AT2) receptor agonists and uses thereof.
WO2013119870A1 (en) 2012-02-10 2013-08-15 Tarix Pharmaceuticals Ltd. Compositions and methods for treatment of peripheral vascular disease
US8633158B1 (en) 2012-10-02 2014-01-21 Tarix Pharmaceuticals Ltd. Angiotensin in treating brain conditions
US9333233B2 (en) 2014-02-25 2016-05-10 Tarix Pharmaceuticals Ltd. Methods and compositions for the delayed treatment of stroke

Also Published As

Publication number Publication date
AU2013327453A1 (en) 2015-04-09
US20140094497A1 (en) 2014-04-03
WO2014055591A1 (en) 2014-04-10
ES2689781T3 (es) 2018-11-15
US20190000809A1 (en) 2019-01-03
CN104837485A (zh) 2015-08-12
EP2903605B1 (en) 2018-08-15
JP2015532291A (ja) 2015-11-09
MX366134B (es) 2019-06-28
RU2018120387A (ru) 2018-11-15
JP2018090625A (ja) 2018-06-14
EP2903605A4 (en) 2016-03-23
JP6302916B2 (ja) 2018-03-28
JP6472914B2 (ja) 2019-02-20
AU2018205186B2 (en) 2020-04-09
AU2018205186A1 (en) 2018-08-02
US8633158B1 (en) 2014-01-21
RU2661109C2 (ru) 2018-07-11
KR20150067228A (ko) 2015-06-17
CA2885912A1 (en) 2014-04-10
RU2015110114A (ru) 2016-11-27
EP2903605A1 (en) 2015-08-12
US20170258766A1 (en) 2017-09-14
US9511055B2 (en) 2016-12-06

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