MX2014000522A - Composicion y metodo para tratar virus del papiloma humano (vph). - Google Patents
Composicion y metodo para tratar virus del papiloma humano (vph).Info
- Publication number
- MX2014000522A MX2014000522A MX2014000522A MX2014000522A MX2014000522A MX 2014000522 A MX2014000522 A MX 2014000522A MX 2014000522 A MX2014000522 A MX 2014000522A MX 2014000522 A MX2014000522 A MX 2014000522A MX 2014000522 A MX2014000522 A MX 2014000522A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- hpv
- relates
- composition
- present
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 241000701806 Human papillomavirus Species 0.000 abstract 4
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 abstract 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 abstract 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 abstract 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 2
- 206010008342 Cervix carcinoma Diseases 0.000 abstract 1
- VWFCHDSQECPREK-LURJTMIESA-N Cidofovir Chemical compound NC=1C=CN(C[C@@H](CO)OCP(O)(O)=O)C(=O)N=1 VWFCHDSQECPREK-LURJTMIESA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 abstract 1
- 201000010881 cervical cancer Diseases 0.000 abstract 1
- 229960000724 cidofovir Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 230000036210 malignancy Effects 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Inorganic Chemistry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Dermatology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a composiciones liofilizadas que comprenden cidofovir, hidroxipropilmetilcelulosa (HPMC) o hidroexietilcelulosa (HEC) y opcionalmente un plastificante. En particular, la presente invención se refiere a tales composiciones que forman una matriz sólida porosa en forma de hoja. La invención también se refiere a métodos para producir tales composiciones. La invención se refiere además a tales composiciones para utilizar en el tratamiento de infecciones por virus del papiloma humano (HPV) y malignidades asociadas con HPV, en particular lesiones por HPV y cáncer cervical.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161508473P | 2011-07-15 | 2011-07-15 | |
| EP11174193 | 2011-07-15 | ||
| PCT/EP2012/063796 WO2013010942A1 (en) | 2011-07-15 | 2012-07-13 | Composition and method for treating hpv |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2014000522A true MX2014000522A (es) | 2014-05-30 |
Family
ID=45877205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014000522A MX2014000522A (es) | 2011-07-15 | 2012-07-13 | Composicion y metodo para tratar virus del papiloma humano (vph). |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9211338B2 (es) |
| EP (1) | EP2731588B1 (es) |
| JP (1) | JP2014520834A (es) |
| KR (1) | KR20140054067A (es) |
| CN (1) | CN103889400A (es) |
| AU (1) | AU2012285969A1 (es) |
| BR (1) | BR112014000877A2 (es) |
| CA (1) | CA2841851A1 (es) |
| CL (1) | CL2014000110A1 (es) |
| EA (1) | EA201490220A1 (es) |
| MX (1) | MX2014000522A (es) |
| WO (1) | WO2013010942A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013010942A1 (en) | 2011-07-15 | 2013-01-24 | Femalon S.A. | Composition and method for treating hpv |
| US20200253994A1 (en) * | 2019-02-11 | 2020-08-13 | Chemistryrx | Pyrimidine derivative containing compositions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020039594A1 (en) * | 1997-05-13 | 2002-04-04 | Evan C. Unger | Solid porous matrices and methods of making and using the same |
| US8178123B2 (en) * | 2001-08-29 | 2012-05-15 | Femina Pharma Incorporated | Method for augmentation of intraepithelial and systemic exposure of therapeutic agents having substrate activity for cytochrome P450 enzymes and membrane efflux systems following vaginal and oral cavity administration |
| US8907153B2 (en) * | 2004-06-07 | 2014-12-09 | Nuvo Research Inc. | Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same |
| CN1698643A (zh) * | 2005-05-27 | 2005-11-23 | 山东恒瑞医药科技发展有限公司 | 西多福韦脂质体及其制备方法 |
| WO2007035515A2 (en) * | 2005-09-15 | 2007-03-29 | Umd, Inc. | A method of intraepithelial and systemic exposure of therapeutic agents following vaginal and oral cavity administration |
| EP1837020A1 (en) | 2006-03-24 | 2007-09-26 | Bioalliance Pharma | Mucosal bioadhesive slow release carrier for delivering active principles |
| WO2013010942A1 (en) | 2011-07-15 | 2013-01-24 | Femalon S.A. | Composition and method for treating hpv |
-
2012
- 2012-07-13 WO PCT/EP2012/063796 patent/WO2013010942A1/en not_active Ceased
- 2012-07-13 AU AU2012285969A patent/AU2012285969A1/en not_active Abandoned
- 2012-07-13 CN CN201280044697.1A patent/CN103889400A/zh active Pending
- 2012-07-13 MX MX2014000522A patent/MX2014000522A/es unknown
- 2012-07-13 KR KR1020147003884A patent/KR20140054067A/ko not_active Withdrawn
- 2012-07-13 US US14/232,529 patent/US9211338B2/en not_active Expired - Fee Related
- 2012-07-13 CA CA2841851A patent/CA2841851A1/en not_active Abandoned
- 2012-07-13 JP JP2014519572A patent/JP2014520834A/ja active Pending
- 2012-07-13 EP EP12742822.5A patent/EP2731588B1/en active Active
- 2012-07-13 EA EA201490220A patent/EA201490220A1/ru unknown
- 2012-07-13 BR BR112014000877A patent/BR112014000877A2/pt not_active IP Right Cessation
-
2014
- 2014-01-15 CL CL2014000110A patent/CL2014000110A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140054067A (ko) | 2014-05-08 |
| BR112014000877A2 (pt) | 2017-02-21 |
| NZ620042A (en) | 2015-09-25 |
| US20140170219A1 (en) | 2014-06-19 |
| CN103889400A (zh) | 2014-06-25 |
| CL2014000110A1 (es) | 2014-10-24 |
| WO2013010942A1 (en) | 2013-01-24 |
| CA2841851A1 (en) | 2013-01-24 |
| EA201490220A1 (ru) | 2014-07-30 |
| AU2012285969A1 (en) | 2014-01-30 |
| JP2014520834A (ja) | 2014-08-25 |
| US9211338B2 (en) | 2015-12-15 |
| EP2731588B1 (en) | 2016-04-06 |
| EP2731588A1 (en) | 2014-05-21 |
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