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MX2013006546A - Metodo, sistema y aparato para controlar la funcion de celulas beta pancreaticas para mejorar la homeostasis de glucosa y la produccion de insulina. - Google Patents

Metodo, sistema y aparato para controlar la funcion de celulas beta pancreaticas para mejorar la homeostasis de glucosa y la produccion de insulina.

Info

Publication number
MX2013006546A
MX2013006546A MX2013006546A MX2013006546A MX2013006546A MX 2013006546 A MX2013006546 A MX 2013006546A MX 2013006546 A MX2013006546 A MX 2013006546A MX 2013006546 A MX2013006546 A MX 2013006546A MX 2013006546 A MX2013006546 A MX 2013006546A
Authority
MX
Mexico
Prior art keywords
insulin production
control
cell function
beta cell
pancreatic beta
Prior art date
Application number
MX2013006546A
Other languages
English (en)
Inventor
Laura Tyler Perryman
Original Assignee
Neural Diabetes Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neural Diabetes Llc filed Critical Neural Diabetes Llc
Publication of MX2013006546A publication Critical patent/MX2013006546A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36057—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for stimulating afferent nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36121—Production of neurotransmitters; Modulation of genes expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/22—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of calcitonin

Landscapes

  • Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Neurosurgery (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención proporciona métodos, sistemas y aparatos para efectuar la excitación o inhibición de fibras nerviosas sensoriales pequeñas, tales como las fibras aferentes tipo C, mediante la estimulación eléctrica de los nervios que inervan el páncreas en sujetos diabéticos. En un aspecto, los métodos se enfocan en efectuar la producción de insulina para el tratamiento de la diabetes. Esta invención incluye un sistema de control de retroalimentación de bucle cerrado o abierto en el que los niveles de un biomarcador se monitorean para aplicar una estimulación eléctrica directa. Se proporciona un dispositivo de estimulación neural implantable o externo.
MX2013006546A 2010-12-17 2011-12-16 Metodo, sistema y aparato para controlar la funcion de celulas beta pancreaticas para mejorar la homeostasis de glucosa y la produccion de insulina. MX2013006546A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201061424546P 2010-12-17 2010-12-17
PCT/US2011/065653 WO2012083259A2 (en) 2010-12-17 2011-12-16 Method, system and apparatus for control of pancreatic beta cell function to improve glucose homeostatis and insulin production

Publications (1)

Publication Number Publication Date
MX2013006546A true MX2013006546A (es) 2013-09-05

Family

ID=46245408

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013006546A MX2013006546A (es) 2010-12-17 2011-12-16 Metodo, sistema y aparato para controlar la funcion de celulas beta pancreaticas para mejorar la homeostasis de glucosa y la produccion de insulina.

Country Status (7)

Country Link
US (2) US8903501B2 (es)
EP (1) EP2651431B1 (es)
AU (1) AU2011343512A1 (es)
CA (1) CA2822079A1 (es)
DK (1) DK2651431T3 (es)
MX (1) MX2013006546A (es)
WO (1) WO2012083259A2 (es)

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Also Published As

Publication number Publication date
DK2651431T3 (en) 2018-06-14
WO2012083259A3 (en) 2013-09-12
EP2651431A4 (en) 2014-07-30
US20120303098A1 (en) 2012-11-29
EP2651431B1 (en) 2018-03-07
US20150073510A1 (en) 2015-03-12
WO2012083259A2 (en) 2012-06-21
AU2011343512A1 (en) 2013-06-13
EP2651431A2 (en) 2013-10-23
CA2822079A1 (en) 2012-06-21
US8903501B2 (en) 2014-12-02

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