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MX2013005644A - Suministro local vascular de agonistas del receptor de adenosina a2a para reducir el daño al miocardio. - Google Patents

Suministro local vascular de agonistas del receptor de adenosina a2a para reducir el daño al miocardio.

Info

Publication number
MX2013005644A
MX2013005644A MX2013005644A MX2013005644A MX2013005644A MX 2013005644 A MX2013005644 A MX 2013005644A MX 2013005644 A MX2013005644 A MX 2013005644A MX 2013005644 A MX2013005644 A MX 2013005644A MX 2013005644 A MX2013005644 A MX 2013005644A
Authority
MX
Mexico
Prior art keywords
stent
myocardial injury
receptor agonist
adenosine receptor
selective adenosine
Prior art date
Application number
MX2013005644A
Other languages
English (en)
Inventor
Robert Falotico
Theodore L Parker
Original Assignee
Cordis Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cordis Corp filed Critical Cordis Corp
Publication of MX2013005644A publication Critical patent/MX2013005644A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/06Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se puede usar una endoprótesis u otro dispositivo médico implantable para el suministro local de un agonista selectivo del receptor de adenosina para reducir la lesión miocárdica después de un infarto agudo del miocardio; tan pronto como sea posible después de un infarto agudo del miocardio, se coloca una endoprótesis u otro dispositivo adecuado que comprende y es capaz de suministrar un agonista selectivo del receptor de adenosina en el vaso sanguíneo con la oclusión responsable de causar el infarto; una vez en posición, la endoprótesis u otro dispositivo intraluminal se despliega para eliminar la oclusión y restablecer el flujo sanguíneo al área, región o volumen de tejido específico del corazón; durante un período de tiempo el agonista selectivo del receptor de adenosina eluye de la endoprótesis u otro dispositivo hacia el flujo sanguíneo coronario corriente abajo hacia el tejido cardíaco hipóxico durante un tiempo suficiente para reducir el nivel de daño miocárdico.
MX2013005644A 2010-11-18 2011-11-09 Suministro local vascular de agonistas del receptor de adenosina a2a para reducir el daño al miocardio. MX2013005644A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41504510P 2010-11-18 2010-11-18
US12/971,037 US20120130480A1 (en) 2010-11-18 2010-12-17 Local vascular delivery of adenosine a2a receptor agonists to reduce myocardial injury
PCT/US2011/059993 WO2012067912A1 (en) 2010-11-18 2011-11-09 Local vascular delivery of adenosine a2a receptor agonists to reduce myocardial injury

Publications (1)

Publication Number Publication Date
MX2013005644A true MX2013005644A (es) 2013-07-03

Family

ID=46065054

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013005644A MX2013005644A (es) 2010-11-18 2011-11-09 Suministro local vascular de agonistas del receptor de adenosina a2a para reducir el daño al miocardio.

Country Status (12)

Country Link
US (1) US20120130480A1 (es)
EP (1) EP2640433A1 (es)
JP (1) JP6042342B2 (es)
KR (1) KR20130130745A (es)
CN (1) CN103209719A (es)
AU (1) AU2011329269B2 (es)
BR (1) BR112013011880B1 (es)
CA (1) CA2815382A1 (es)
IL (1) IL225642A0 (es)
MX (1) MX2013005644A (es)
RU (1) RU2013127579A (es)
WO (1) WO2012067912A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6235345B2 (ja) 2011-03-08 2017-11-22 ダブリュ.エル.ゴア アンド アソシエイツ,インコーポレイティドW.L. Gore & Associates, Incorporated ストーマと共に使用するための医療装置
US9993251B2 (en) 2014-05-02 2018-06-12 W. L. Gore & Associates, Inc. Anastomosis devices
US11439396B2 (en) 2014-05-02 2022-09-13 W. L. Gore & Associates, Inc. Occluder and anastomosis devices
US11712230B2 (en) 2014-05-02 2023-08-01 W. L. Gore & Associates, Inc. Occluder and anastomosis devices
WO2016004441A1 (en) * 2014-07-03 2016-01-07 Stealth Peptides International, Inc. Methods for the prevention or treatment of acute myocardial infarction injury
US11724075B2 (en) 2017-04-18 2023-08-15 W. L. Gore & Associates, Inc. Deployment constraining sheath that enables staged deployment by device section
US12090072B2 (en) * 2018-11-13 2024-09-17 Icad Endovascular Llc Systems and methods for delivery retrievable stents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843172A (en) * 1997-04-15 1998-12-01 Advanced Cardiovascular Systems, Inc. Porous medicated stent
US20030077312A1 (en) * 2001-10-22 2003-04-24 Ascher Schmulewicz Coated intraluminal stents and reduction of restenosis using same
US20050220836A1 (en) * 2004-03-31 2005-10-06 Robert Falotico Drug delivery device
US20070269486A1 (en) * 2005-03-14 2007-11-22 Conor Medsystems, Llc. Methods and Devices for Reducing Tissue Damage After Ischemic Injury
US20070212387A1 (en) * 2006-03-08 2007-09-13 Sahajanand Medical Technologies Pvt. Ltd. Coatings for implantable medical devices
WO2007134271A2 (en) * 2006-05-15 2007-11-22 Innovational Holdings Llc Method and apparatus for reducing injury from acute myocardial infarction
US20100161039A1 (en) * 2008-12-23 2010-06-24 Vipul Dave Adhesion promoting temporary mask for coated surfaces

Also Published As

Publication number Publication date
JP2014502192A (ja) 2014-01-30
WO2012067912A1 (en) 2012-05-24
KR20130130745A (ko) 2013-12-02
BR112013011880B1 (pt) 2019-01-22
CN103209719A (zh) 2013-07-17
IL225642A0 (en) 2013-06-27
JP6042342B2 (ja) 2016-12-14
BR112013011880A2 (pt) 2018-01-23
AU2011329269A1 (en) 2013-05-02
RU2013127579A (ru) 2014-12-27
AU2011329269B2 (en) 2015-01-22
US20120130480A1 (en) 2012-05-24
CA2815382A1 (en) 2012-05-24
EP2640433A1 (en) 2013-09-25

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