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MX2013002656A - Nuevo proceso. - Google Patents

Nuevo proceso.

Info

Publication number
MX2013002656A
MX2013002656A MX2013002656A MX2013002656A MX2013002656A MX 2013002656 A MX2013002656 A MX 2013002656A MX 2013002656 A MX2013002656 A MX 2013002656A MX 2013002656 A MX2013002656 A MX 2013002656A MX 2013002656 A MX2013002656 A MX 2013002656A
Authority
MX
Mexico
Prior art keywords
new process
preparation
intermediates
useful
compound
Prior art date
Application number
MX2013002656A
Other languages
English (en)
Inventor
Reinhard Reents
Gerard John Harnett
Dennis A Smith
John Hayes
Andrew Walsh
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2013002656A publication Critical patent/MX2013002656A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/06—Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C07C319/06—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols from sulfides, hydropolysulfides or polysulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
    • C07C321/24—Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
    • C07C321/28—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/30—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/06—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a un proceso para la preparación de un compuesto de la fórmula (I) que es útil como un compuesto intermedio en la preparación de los compuestos activos farmacéuticamente.
MX2013002656A 2010-09-16 2011-09-13 Nuevo proceso. MX2013002656A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10177187 2010-09-16
PCT/EP2011/065860 WO2012035017A1 (en) 2010-09-16 2011-09-13 New process

Publications (1)

Publication Number Publication Date
MX2013002656A true MX2013002656A (es) 2013-04-08

Family

ID=43242302

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013002656A MX2013002656A (es) 2010-09-16 2011-09-13 Nuevo proceso.

Country Status (11)

Country Link
US (5) US20120071683A1 (es)
EP (1) EP2616433B1 (es)
JP (1) JP2013540736A (es)
KR (1) KR20130100124A (es)
CN (1) CN103097345A (es)
BR (1) BR112013004557A2 (es)
CA (1) CA2809215A1 (es)
ES (1) ES2557559T3 (es)
MX (1) MX2013002656A (es)
RU (1) RU2013114350A (es)
WO (1) WO2012035017A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2978859T (pt) 2013-03-27 2018-10-04 Hoffmann La Roche Marcadores genéticos para previsão da capacidade de resposta à terapêutica
ES2825675T3 (es) 2014-07-30 2021-05-17 Hoffmann La Roche Marcadores genéticos para predecir la reactividad al tratamiento con un agente que aumenta las HDL o que imita las HDL

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK311477A (da) 1977-07-08 1979-01-09 Leo Lab Fremgangsmaade ved fremstilling af rent insulin
EP0001020A1 (en) 1977-08-31 1979-03-07 Gordon Hoy Tipping vehicle
MX2007013450A (es) * 2005-04-29 2008-01-21 Wyeth Corp Procedimniento de preparacion de oxindoles y tio-oxindoles 3,3-disustituidos.
US7435849B2 (en) 2005-10-31 2008-10-14 Hoffmann-La Roche Inc. Process for the production of acid chlorides
EP2274278B1 (en) * 2008-04-04 2016-08-17 F. Hoffmann-La Roche AG New process for the preparatiion of cyclohexanecarboxylic acid dericatives
JP2011519935A (ja) * 2008-05-08 2011-07-14 エフ．ホフマン−ラ ロシュ アーゲー １−（２−エチルブチル）シクロヘキサンカルボニトリルの合成方法

Also Published As

Publication number Publication date
US20150361034A1 (en) 2015-12-17
JP2013540736A (ja) 2013-11-07
US20120071683A1 (en) 2012-03-22
US20130197257A1 (en) 2013-08-01
US20160200672A1 (en) 2016-07-14
ES2557559T3 (es) 2016-01-27
WO2012035017A1 (en) 2012-03-22
CN103097345A (zh) 2013-05-08
CA2809215A1 (en) 2012-03-22
US20140336403A1 (en) 2014-11-13
EP2616433B1 (en) 2015-12-09
KR20130100124A (ko) 2013-09-09
RU2013114350A (ru) 2014-10-27
EP2616433A1 (en) 2013-07-24
BR112013004557A2 (pt) 2016-09-06

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