MX2012012489A - Preparacion de polipeptidos y sales de los mismos. - Google Patents
Preparacion de polipeptidos y sales de los mismos.Info
- Publication number
- MX2012012489A MX2012012489A MX2012012489A MX2012012489A MX2012012489A MX 2012012489 A MX2012012489 A MX 2012012489A MX 2012012489 A MX2012012489 A MX 2012012489A MX 2012012489 A MX2012012489 A MX 2012012489A MX 2012012489 A MX2012012489 A MX 2012012489A
- Authority
- MX
- Mexico
- Prior art keywords
- polypeptides
- salts
- preparation
- processes
- preparing
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title 1
- 108010072051 Glatiramer Acetate Proteins 0.000 abstract 1
- FHEAIOHRHQGZPC-KIWGSFCNSA-N acetic acid;(2s)-2-amino-3-(4-hydroxyphenyl)propanoic acid;(2s)-2-aminopentanedioic acid;(2s)-2-aminopropanoic acid;(2s)-2,6-diaminohexanoic acid Chemical compound CC(O)=O.C[C@H](N)C(O)=O.NCCCC[C@H](N)C(O)=O.OC(=O)[C@@H](N)CCC(O)=O.OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 FHEAIOHRHQGZPC-KIWGSFCNSA-N 0.000 abstract 1
- 229960003776 glatiramer acetate Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
- C08G69/10—Alpha-amino-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/48—Polymers modified by chemical after-treatment
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polyamides (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente invención se refiere procesos para preparar polipéptidos. También se proporcionan procesos para preparar acetato de glatirámero.
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1166CH2010 | 2010-04-27 | ||
| IN1457CH2010 | 2010-05-27 | ||
| US35610510P | 2010-06-18 | 2010-06-18 | |
| IN2845CH2010 | 2010-09-27 | ||
| US41613210P | 2010-11-22 | 2010-11-22 | |
| PCT/US2011/034102 WO2011139752A2 (en) | 2010-04-27 | 2011-04-27 | Preparation of polypeptides and salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012012489A true MX2012012489A (es) | 2012-12-17 |
Family
ID=44904352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012012489A MX2012012489A (es) | 2010-04-27 | 2011-04-27 | Preparacion de polipeptidos y sales de los mismos. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20130281663A1 (es) |
| EP (1) | EP2563804A4 (es) |
| JP (1) | JP2013529194A (es) |
| KR (1) | KR20130062936A (es) |
| CN (1) | CN102844325A (es) |
| AU (1) | AU2011248663A1 (es) |
| BR (1) | BR112012027753A2 (es) |
| CA (1) | CA2797227A1 (es) |
| IL (1) | IL222714A0 (es) |
| MX (1) | MX2012012489A (es) |
| NZ (1) | NZ603012A (es) |
| RU (1) | RU2012150443A (es) |
| WO (1) | WO2011139752A2 (es) |
| ZA (1) | ZA201207675B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130043196A (ko) * | 2010-07-29 | 2013-04-29 | 닥터 레디스 래보러토리즈, 인코포레이티드 | 글라티라머 아세테이트 분자량 마커 |
| CN104371012A (zh) * | 2013-08-12 | 2015-02-25 | 深圳翰宇药业股份有限公司 | 一种合成醋酸格拉替雷的方法 |
| CN105223281B (zh) * | 2014-06-24 | 2017-09-05 | 深圳翰宇药业股份有限公司 | 一种用于检测卡帕松制剂中醋酸格拉替雷浓度的色谱方法 |
| CN104297404B (zh) * | 2014-09-26 | 2016-08-24 | 深圳翰宇药业股份有限公司 | 一种用于测定醋酸格拉替雷样品中哌啶杂质含量的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL113812A (en) * | 1994-05-24 | 2000-06-29 | Yeda Res & Dev | Copolymer-1 pharmaceutical compositions containing it and its use |
| KR101317131B1 (ko) * | 2004-09-09 | 2013-10-10 | 테바 파마슈티컬 인더스트리즈 리미티드 | 정제된 브롬화 수소산을 이용한 폴리펩타이드류의 혼합물의제조방법 |
| WO2006050122A1 (en) * | 2004-10-29 | 2006-05-11 | Sandoz Ag | Processes for preparing glatiramer |
| EP1922345A4 (en) * | 2005-08-15 | 2009-11-11 | Chan Wai Hong | PROCESS FOR THE PREPARATION OF COPOLYMER-1 |
| WO2007030573A2 (en) * | 2005-09-09 | 2007-03-15 | Yeda Research And Development Co. Ltd. | Polypeptides useful for molecular weight determinations |
| ATE452140T1 (de) * | 2006-07-05 | 2010-01-15 | Momenta Pharmaceuticals Inc | Verbessertes verfahren zur herstellung von copolymer-1 |
| EP2173766A1 (en) * | 2007-07-31 | 2010-04-14 | Natco Pharma Limited | Process for the preparation glatiramer acetate (copolymer-1) |
-
2011
- 2011-04-27 MX MX2012012489A patent/MX2012012489A/es not_active Application Discontinuation
- 2011-04-27 AU AU2011248663A patent/AU2011248663A1/en not_active Abandoned
- 2011-04-27 US US13/639,271 patent/US20130281663A1/en not_active Abandoned
- 2011-04-27 EP EP11777947.0A patent/EP2563804A4/en not_active Withdrawn
- 2011-04-27 JP JP2013508200A patent/JP2013529194A/ja active Pending
- 2011-04-27 BR BR112012027753A patent/BR112012027753A2/pt not_active IP Right Cessation
- 2011-04-27 RU RU2012150443/04A patent/RU2012150443A/ru not_active Application Discontinuation
- 2011-04-27 NZ NZ603012A patent/NZ603012A/en not_active IP Right Cessation
- 2011-04-27 CA CA 2797227 patent/CA2797227A1/en not_active Abandoned
- 2011-04-27 KR KR1020127030888A patent/KR20130062936A/ko not_active Withdrawn
- 2011-04-27 WO PCT/US2011/034102 patent/WO2011139752A2/en not_active Ceased
- 2011-04-27 CN CN2011800194919A patent/CN102844325A/zh active Pending
-
2012
- 2012-10-12 ZA ZA2012/07675A patent/ZA201207675B/en unknown
- 2012-10-25 IL IL222714A patent/IL222714A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2563804A4 (en) | 2014-09-17 |
| IL222714A0 (en) | 2012-12-31 |
| US20130281663A1 (en) | 2013-10-24 |
| AU2011248663A1 (en) | 2012-11-08 |
| CA2797227A1 (en) | 2011-11-10 |
| WO2011139752A2 (en) | 2011-11-10 |
| CN102844325A (zh) | 2012-12-26 |
| WO2011139752A3 (en) | 2012-04-05 |
| KR20130062936A (ko) | 2013-06-13 |
| NZ603012A (en) | 2015-01-30 |
| EP2563804A2 (en) | 2013-03-06 |
| BR112012027753A2 (pt) | 2017-01-10 |
| JP2013529194A (ja) | 2013-07-18 |
| ZA201207675B (en) | 2013-06-26 |
| RU2012150443A (ru) | 2014-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |