MX2012010382A - Modulacion de acuaporinas con relaxina. - Google Patents
Modulacion de acuaporinas con relaxina.Info
- Publication number
- MX2012010382A MX2012010382A MX2012010382A MX2012010382A MX2012010382A MX 2012010382 A MX2012010382 A MX 2012010382A MX 2012010382 A MX2012010382 A MX 2012010382A MX 2012010382 A MX2012010382 A MX 2012010382A MX 2012010382 A MX2012010382 A MX 2012010382A
- Authority
- MX
- Mexico
- Prior art keywords
- modulating
- relaxin
- aquaporins
- methods
- aquaporin channels
- Prior art date
Links
- 108010063290 Aquaporins Proteins 0.000 title abstract 3
- 102000003743 Relaxin Human genes 0.000 title abstract 2
- 108090000103 Relaxin Proteins 0.000 title abstract 2
- 102000010637 Aquaporins Human genes 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2221—Relaxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Gynecology & Obstetrics (AREA)
Abstract
La presente invención se refiere a métodos para modular los canales de acuaporina. Particularmente, la invención proporciona métodos para modular los canales de acuaporina en un tejido de un mamífero, mediante la administración de relaxina.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33998110P | 2010-03-10 | 2010-03-10 | |
| US34034910P | 2010-03-15 | 2010-03-15 | |
| PCT/US2011/027859 WO2011112791A1 (en) | 2010-03-10 | 2011-03-10 | Modulating aquaporins with relaxin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012010382A true MX2012010382A (es) | 2013-01-29 |
Family
ID=43901111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012010382A MX2012010382A (es) | 2010-03-10 | 2011-03-10 | Modulacion de acuaporinas con relaxina. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20130053318A1 (es) |
| EP (1) | EP2544706B1 (es) |
| JP (1) | JP5970380B2 (es) |
| KR (1) | KR101800040B1 (es) |
| CN (1) | CN102883742B (es) |
| AU (1) | AU2011224341B2 (es) |
| BR (1) | BR112012022654A2 (es) |
| CA (1) | CA2791741C (es) |
| ES (1) | ES2541301T3 (es) |
| MX (1) | MX2012010382A (es) |
| RU (1) | RU2564900C2 (es) |
| WO (1) | WO2011112791A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140059168A (ko) | 2011-04-21 | 2014-05-15 | 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 | 시신경 척수염 치료용 조성물 및 치료 방법 |
| US10493131B2 (en) * | 2011-08-31 | 2019-12-03 | University Of Florida Research Foundation, Incorporated | Materials and methods for modulating activity of bone marrow derived cells |
| WO2013053076A1 (en) | 2011-10-10 | 2013-04-18 | Zensun (Shanghai)Science & Technology Limited | Compositions and methods for treating heart failure |
| BR112014027983B1 (pt) | 2012-05-08 | 2022-05-24 | Aeromics, Inc | Uso de inibidores de aquaporina seletivos |
| BR112015029293A2 (pt) | 2013-05-22 | 2018-04-24 | Zensun Shanghai Science & Tech Ltd | método e kit para prevenir, tratar ou retardar uma doença ou distúrbio cardiovascular em um mamífero |
| WO2015069961A1 (en) | 2013-11-06 | 2015-05-14 | Aeromics, Llc | Novel prodrug salts |
| GB201516068D0 (en) * | 2015-09-10 | 2015-10-28 | Biomed Ltd B V | Novel therapy |
| EP4011919A3 (en) | 2015-12-09 | 2022-10-12 | The Scripps Research Institute | Relaxin immunoglobulin fusion proteins and methods of use |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5023321A (en) | 1982-12-13 | 1991-06-11 | Howard Florey Institute Of Experimental Physiology & Medicine | Molecular cloning and characterization of a further gene sequence coding for human relaxin |
| US4686103A (en) * | 1985-07-25 | 1987-08-11 | Iowa State University Research Foundation, Inc. | Method of managing cattle breeding herds |
| WO1989007945A1 (en) * | 1988-02-26 | 1989-09-08 | Genentech, Inc. | Human relaxin formulation |
| US5166191A (en) | 1991-08-19 | 1992-11-24 | Genentech, Inc. | Use of relaxin in cardiovascular therapy |
| EP0707650B1 (en) | 1993-06-21 | 2003-05-21 | Genentech, Inc. | Process for producing human relaxin |
| EP0675732B1 (en) * | 1993-07-27 | 2006-06-28 | Mario Bigazzi | Use of relaxin in the manufacture of therapeutic agents |
| US5811395A (en) | 1995-06-07 | 1998-09-22 | Medical University Of South Carolina | Relaxin analogs and derivatives methods and uses thereof |
| US5612051A (en) * | 1995-11-17 | 1997-03-18 | Yue; Samuel K. | Method of treating involuntary muscle dysfunction with relaxin hormone |
| DE60128540T2 (de) | 2000-02-09 | 2008-01-31 | Bas Medical, Inc., San Mateo | Verwendung von relaxin zur behandlung von durch gefässverengung bedingten erkrankungen |
| US6436448B1 (en) * | 2001-06-25 | 2002-08-20 | Sky Biohealth Solutions, Inc. | Method for the treatment of lymphedema using guaifenesin |
| JP2009079042A (ja) * | 2007-09-07 | 2009-04-16 | Univ Nagoya | 腎性尿崩症治療用組換えベクター及びその用途 |
| AR071810A1 (es) * | 2008-05-16 | 2010-07-14 | Corthera Inc | Metodo de tratamiento de la disnea asociada con la insuficiencia cardiaca aguda. relaxina h2. uso. |
| WO2009140657A2 (en) | 2008-05-16 | 2009-11-19 | Corthera, Inc. | Method of treating chronic heart failure |
-
2011
- 2011-03-10 RU RU2012142985/15A patent/RU2564900C2/ru active
- 2011-03-10 WO PCT/US2011/027859 patent/WO2011112791A1/en not_active Ceased
- 2011-03-10 MX MX2012010382A patent/MX2012010382A/es active IP Right Grant
- 2011-03-10 JP JP2012557239A patent/JP5970380B2/ja not_active Expired - Fee Related
- 2011-03-10 BR BR112012022654A patent/BR112012022654A2/pt not_active Application Discontinuation
- 2011-03-10 ES ES11709841.8T patent/ES2541301T3/es active Active
- 2011-03-10 KR KR1020127026371A patent/KR101800040B1/ko not_active Expired - Fee Related
- 2011-03-10 AU AU2011224341A patent/AU2011224341B2/en not_active Ceased
- 2011-03-10 EP EP11709841.8A patent/EP2544706B1/en not_active Not-in-force
- 2011-03-10 US US13/582,478 patent/US20130053318A1/en not_active Abandoned
- 2011-03-10 CN CN201180013013.7A patent/CN102883742B/zh not_active Expired - Fee Related
- 2011-03-10 CA CA2791741A patent/CA2791741C/en active Active
-
2013
- 2013-11-08 US US14/074,759 patent/US9119833B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR101800040B1 (ko) | 2017-11-21 |
| EP2544706A1 (en) | 2013-01-16 |
| ES2541301T3 (es) | 2015-07-17 |
| CN102883742A (zh) | 2013-01-16 |
| CA2791741C (en) | 2019-04-23 |
| CN102883742B (zh) | 2014-09-24 |
| KR20130058669A (ko) | 2013-06-04 |
| RU2564900C2 (ru) | 2015-10-10 |
| AU2011224341B2 (en) | 2014-07-10 |
| CA2791741A1 (en) | 2011-09-15 |
| WO2011112791A1 (en) | 2011-09-15 |
| BR112012022654A2 (pt) | 2016-11-01 |
| US20130053318A1 (en) | 2013-02-28 |
| JP2013522225A (ja) | 2013-06-13 |
| EP2544706B1 (en) | 2015-06-17 |
| US20140066377A1 (en) | 2014-03-06 |
| RU2012142985A (ru) | 2014-04-20 |
| US9119833B2 (en) | 2015-09-01 |
| JP5970380B2 (ja) | 2016-08-17 |
| AU2011224341A1 (en) | 2012-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |