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MX2012000948A - Anillo vaginal gradiente multicapas. - Google Patents

Anillo vaginal gradiente multicapas.

Info

Publication number
MX2012000948A
MX2012000948A MX2012000948A MX2012000948A MX2012000948A MX 2012000948 A MX2012000948 A MX 2012000948A MX 2012000948 A MX2012000948 A MX 2012000948A MX 2012000948 A MX2012000948 A MX 2012000948A MX 2012000948 A MX2012000948 A MX 2012000948A
Authority
MX
Mexico
Prior art keywords
pharmaceutically active
layers
vaginal ring
disclosed
active ingredient
Prior art date
Application number
MX2012000948A
Other languages
English (en)
Inventor
Bruce Variano
Jeffrey Speck
Maria Teresa Sallent
Simone Evans
Original Assignee
Population Council Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Population Council Inc filed Critical Population Council Inc
Publication of MX2012000948A publication Critical patent/MX2012000948A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Se describen anillos vaginales multicapas 2 que comprenden elastómeros de silicona e ingredientes farmacéuticamente activos. Los anillos comprenden un cierto número de capas, al menos una de las cuales contiene un ingrediente farmacéuticamente activo, y cada una de las cuales es un elastómero de silicona. Preferentemente, las múltiples capas se producen a partir de estas capas de diferentes composiciones, que incluyen una capa interior 4, una capa intermedia 5, y una capa exterior 6. Sin embargo, después de la extrusión y de la curación simultánea, el anillo 2 incluye un cuerpo contiguo el cual comprende un cuerpo continuo de silicona que proporciona la libre difusión del ingrediente farmacéuticamente activo desde la(s) capa(s) interior(es) 4 hacia la(s) capa(s) exterior(es) 6. También se describen los métodos para producir estos anillos vaginales y el uso de los mismos.
MX2012000948A 2009-07-21 2010-04-07 Anillo vaginal gradiente multicapas. MX2012000948A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27139109P 2009-07-21 2009-07-21
PCT/US2010/030183 WO2011011099A1 (en) 2009-07-21 2010-04-07 Multi-layered gradient vaginal ring

Publications (1)

Publication Number Publication Date
MX2012000948A true MX2012000948A (es) 2012-02-28

Family

ID=42236498

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012000948A MX2012000948A (es) 2009-07-21 2010-04-07 Anillo vaginal gradiente multicapas.

Country Status (14)

Country Link
US (1) US8753667B2 (es)
EP (1) EP2456421B1 (es)
JP (1) JP5690826B2 (es)
CN (1) CN102497855B (es)
AU (1) AU2010274946B2 (es)
BR (1) BR112012001353B8 (es)
CA (1) CA2767967C (es)
CO (1) CO6491080A2 (es)
DK (1) DK2456421T3 (es)
ES (1) ES2626156T3 (es)
IN (1) IN2012DN00711A (es)
MX (1) MX2012000948A (es)
WO (1) WO2011011099A1 (es)
ZA (1) ZA201200809B (es)

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GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
WO2012121767A1 (en) * 2011-03-09 2012-09-13 Arstat, Inc. Treatment of uterine fibroids by intravaginal administration of a low dose of selective progesterone receptor modulator (sprm), anti-progestin, or anti-progestational agent
FR3005417B1 (fr) * 2013-05-10 2015-05-22 Blaise Francois Figuereo Anneau vaginal tri-reservoir, a retro-largage compatible avec les caracteristiques des molecules actives qu'il contient
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10413504B2 (en) * 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
HRP20181794T1 (hr) 2014-06-28 2018-12-28 Laboratorios Andrómaco S.A. Cervikalni pesar koji sadrži progesteron za produljeno, neprekidno i kontinuirano oslobađanje, koji se koristi za spriječavanje prijevremenog porođaja
US9943146B2 (en) 2015-05-27 2018-04-17 Qalo Llc Compression molded silicone ring
CA2984032C (en) * 2015-07-14 2019-10-08 Qalo Llc Compression molded silicone ring
RU2732822C2 (ru) * 2015-12-21 2020-09-22 Байер Ой Способ изготовления устройства доставки лекарственного средства и устройство доставки лекарственного средства, изготовленное указанным способом
EP3272333A1 (en) 2016-07-22 2018-01-24 Chemo Research, S.L. Vaginal composition comprising a combination of estrogen and vitamin d
CN106913412B (zh) * 2017-03-01 2023-09-22 上海市嘉定区妇幼保健院 易放易取式子宫托
WO2019226516A1 (en) 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
MX2020012459A (es) 2018-05-24 2021-04-28 Celanese Eva Performance Polymers Llc Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular.
EP3803866A4 (en) 2018-05-24 2022-03-16 Nureva Inc. METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS
US10918649B2 (en) 2019-06-21 2021-02-16 The Population Council, Inc. System for providing birth control
WO2021096926A1 (en) * 2019-11-12 2021-05-20 Poly-Med, Inc. Contraceptive medical devices
DE102021100916A1 (de) 2021-01-18 2022-07-21 Carl Freudenberg Kg Verfahren zur Herstellung eines Bauteils, Werkzeug zur Durchführung des Verfahrens und Bauteil, das durch das Verfahren hergestellt ist
EP4329734A4 (en) 2021-04-26 2025-04-02 Celanese EVA Performance Polymers LLC Implantable device for the delayed release of a macromolecular drug compound

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US2863846A (en) 1950-05-04 1958-12-09 Dow Corning Organo silyl-silica filled siloxane elastomers and process for producing same
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Also Published As

Publication number Publication date
CA2767967C (en) 2014-10-21
BR112012001353B8 (pt) 2021-05-25
AU2010274946A1 (en) 2012-03-01
US20120148655A1 (en) 2012-06-14
ZA201200809B (en) 2012-10-31
CA2767967A1 (en) 2011-01-27
IN2012DN00711A (es) 2015-06-19
US8753667B2 (en) 2014-06-17
WO2011011099A1 (en) 2011-01-27
CN102497855A (zh) 2012-06-13
HK1169614A1 (en) 2013-02-01
BR112012001353B1 (pt) 2020-04-14
EP2456421B1 (en) 2017-04-05
BR112012001353A2 (pt) 2016-04-05
CN102497855B (zh) 2013-12-25
EP2456421A1 (en) 2012-05-30
JP5690826B2 (ja) 2015-03-25
DK2456421T3 (en) 2017-06-06
ES2626156T3 (es) 2017-07-24
JP2012533401A (ja) 2012-12-27
CO6491080A2 (es) 2012-07-31
AU2010274946B2 (en) 2013-09-12

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