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MX2011012538A - Terapia de combinacion para el tratamiento del mieloma multiple. - Google Patents

Terapia de combinacion para el tratamiento del mieloma multiple.

Info

Publication number
MX2011012538A
MX2011012538A MX2011012538A MX2011012538A MX2011012538A MX 2011012538 A MX2011012538 A MX 2011012538A MX 2011012538 A MX2011012538 A MX 2011012538A MX 2011012538 A MX2011012538 A MX 2011012538A MX 2011012538 A MX2011012538 A MX 2011012538A
Authority
MX
Mexico
Prior art keywords
multiple myeloma
treatment
combination therapy
subject
combination
Prior art date
Application number
MX2011012538A
Other languages
English (en)
Inventor
James R Berenson
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2009/003467 external-priority patent/WO2010138101A1/en
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of MX2011012538A publication Critical patent/MX2011012538A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención provee un método para el tratamiento de mieloma múltiple en un sujeto, que comprende la etapa de administrar al sujeto una combinación del compuesto 1 y bortezomib. La invención provee además un método para el tratamiento de mieloma múltiple en un sujeto, que comprende la etapa de administrar al sujeto una combinación del compuesto 1 y melfalán.
MX2011012538A 2009-05-27 2009-12-08 Terapia de combinacion para el tratamiento del mieloma multiple. MX2011012538A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US18155009P 2009-05-27 2009-05-27
US18550109P 2009-06-09 2009-06-09
PCT/US2009/003467 WO2010138101A1 (en) 2009-05-27 2009-06-09 Combination therapy for the treatment of multiple myeloma using cep-18770 together with bortezomib or mephalan
US23259409P 2009-08-10 2009-08-10
PCT/US2009/067174 WO2010138141A1 (en) 2009-05-27 2009-12-08 Combination therapy for the treatment of multiple myeloma

Publications (1)

Publication Number Publication Date
MX2011012538A true MX2011012538A (es) 2012-02-08

Family

ID=43222992

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011012538A MX2011012538A (es) 2009-05-27 2009-12-08 Terapia de combinacion para el tratamiento del mieloma multiple.

Country Status (7)

Country Link
US (1) US8765720B2 (es)
CN (1) CN102458127B (es)
AU (1) AU2009347159B2 (es)
CA (1) CA2763471A1 (es)
IL (1) IL216491A0 (es)
MX (1) MX2011012538A (es)
WO (1) WO2010138141A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2774930T3 (es) 2012-03-06 2020-07-23 Univ Illinois Activación de procaspasa 3 mediante terapia de combinación
WO2013142376A1 (en) * 2012-03-19 2013-09-26 Aposignal Bioscience Llc Composition and methods for cell modulation
WO2018125968A1 (en) * 2016-12-28 2018-07-05 Emory University Glut4 selective inhibitors for cancer therapy
SG11202004384YA (en) 2017-11-17 2020-06-29 Univ Illinois Cancer therapy by degrading dual mek signaling
WO2020072774A1 (en) 2018-10-05 2020-04-09 The Board Of Trustees Of The University Of Illinois Combination therapy for the treatment of uveal melanoma

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083903A (en) * 1994-10-28 2000-07-04 Leukosite, Inc. Boronic ester and acid compounds, synthesis and uses
ZA200603888B (en) * 2001-06-01 2007-05-30 Wyeth Corp Antineoplastic combinations
US7576206B2 (en) * 2003-08-14 2009-08-18 Cephalon, Inc. Proteasome inhibitors and methods of using the same
GB0426264D0 (en) * 2004-11-30 2004-12-29 Trigen Ltd Compounds
CA2604424A1 (en) * 2005-04-29 2006-11-09 Kosan Biosciences Incorporated Method of treating multiple myeloma using 17-aag or 17-ag or a prodrug of either in combination with a proteasome inhibitor
US8894974B2 (en) * 2006-05-11 2014-11-25 Spectrum Dynamics Llc Radiopharmaceuticals for diagnosis and therapy
JP2010516767A (ja) * 2007-01-23 2010-05-20 グラスター ファーマシューティカルズ， インコーポレイテッド ロミデプシンおよびｉ．ａ．ボルテゾミブを含む併用療法
WO2009061345A2 (en) 2007-11-07 2009-05-14 Cornell Research Foundation, Inc. Targeting cdk4 and cdk6 in cancer therapy

Also Published As

Publication number Publication date
CA2763471A1 (en) 2010-12-02
AU2009347159B2 (en) 2015-09-03
WO2010138141A1 (en) 2010-12-02
CN102458127A (zh) 2012-05-16
IL216491A0 (en) 2012-01-31
US20120071445A1 (en) 2012-03-22
AU2009347159A1 (en) 2011-12-15
CN102458127B (zh) 2014-08-27
US8765720B2 (en) 2014-07-01

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