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MX2011011333A - Composiciones y metodos para tratar la resistencia a la insulina y la diabetes mellituscampo de la invencion. - Google Patents

Composiciones y metodos para tratar la resistencia a la insulina y la diabetes mellituscampo de la invencion.

Info

Publication number
MX2011011333A
MX2011011333A MX2011011333A MX2011011333A MX2011011333A MX 2011011333 A MX2011011333 A MX 2011011333A MX 2011011333 A MX2011011333 A MX 2011011333A MX 2011011333 A MX2011011333 A MX 2011011333A MX 2011011333 A MX2011011333 A MX 2011011333A
Authority
MX
Mexico
Prior art keywords
fluids
electrokinetically
altered
membrane
insulin resistance
Prior art date
Application number
MX2011011333A
Other languages
English (en)
Inventor
Anthony B Wood
Gregory J Archambeau
Richard L Watson
Original Assignee
Revalesio Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Revalesio Corp filed Critical Revalesio Corp
Publication of MX2011011333A publication Critical patent/MX2011011333A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se proporcionan fluidos alterados electrocinéticamente (fluidos electrocinéticos enriquecidos con gas) que comprenden una solución acuosa iónica de nanoestructuras que contienen oxígeno y que tienen carga estabilizada en una cantidad suficiente como para proporcionar la modulación de al menos uno de potencial de membrana celular y conductividad de membrana celular y composiciones y métodos terapéuticos para usarse en el tratamiento de la diabetes y afecciones o trastornos asociados con la diabetes (por ej., resistencia a la insulina) o síntomas de los mismos. Se proporcionan fluidos acuosos iónicos alterados electrocinéticamente opcionalmente en combinación con otros agentes terapéuticos. Aspectos particulares proporcionan la regulación o modulación de transducción de señal intracelular asociada con dichas respuestas inflamatorias por la modulación de al menos uno de membranas celulares, potencial de membrana, proteínas de membrana tales como receptores de membrana, incluyendo pero a modo no taxativo, receptores acoplados a la proteína G (GPCR) y uniones intercelulares (por ej., uniones firmes, uniones de huecos, adherinas de zona y desmasomas) . Otras modalidades incluyen vías de administración o formulaciones particulares para los fluidos alterados electrocinéticamente (por ej., fluidos y soluciones enriquecidos con gas y alterados electrocinéticamente) y composiciones terapéutica:.
MX2011011333A 2009-04-27 2010-04-27 Composiciones y metodos para tratar la resistencia a la insulina y la diabetes mellituscampo de la invencion. MX2011011333A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17313409P 2009-04-27 2009-04-27
PCT/US2010/032620 WO2010126908A1 (en) 2009-04-27 2010-04-27 Compositions and methods for treating insulin resistance and diabetes mellitus

Publications (1)

Publication Number Publication Date
MX2011011333A true MX2011011333A (es) 2011-11-18

Family

ID=43032520

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011011333A MX2011011333A (es) 2009-04-27 2010-04-27 Composiciones y metodos para tratar la resistencia a la insulina y la diabetes mellituscampo de la invencion.

Country Status (9)

Country Link
EP (1) EP2424507A4 (es)
JP (2) JP2012525396A (es)
CN (1) CN102413817B (es)
AU (1) AU2010241736B2 (es)
BR (1) BRPI1013992A2 (es)
CA (1) CA2758738A1 (es)
IL (1) IL215925A0 (es)
MX (1) MX2011011333A (es)
WO (1) WO2010126908A1 (es)

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PE20140960A1 (es) 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
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CN105593363A (zh) * 2013-12-27 2016-05-18 水活力株式会社 含纳米气泡的组合物及其用途
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Also Published As

Publication number Publication date
JP2012525396A (ja) 2012-10-22
CA2758738A1 (en) 2010-11-04
CN102413817A (zh) 2012-04-11
BRPI1013992A2 (pt) 2016-08-16
CN102413817B (zh) 2014-12-17
AU2010241736B2 (en) 2016-01-28
AU2010241736A1 (en) 2011-12-22
IL215925A0 (en) 2011-12-29
WO2010126908A1 (en) 2010-11-04
EP2424507A4 (en) 2012-10-24
EP2424507A1 (en) 2012-03-07
JP2015229678A (ja) 2015-12-21

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