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MX2011008450A - Agonistas y antagonistas del receptor s1p5, y metodos de uso de los mismos. - Google Patents

Agonistas y antagonistas del receptor s1p5, y metodos de uso de los mismos.

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Publication number
MX2011008450A
MX2011008450A MX2011008450A MX2011008450A MX2011008450A MX 2011008450 A MX2011008450 A MX 2011008450A MX 2011008450 A MX2011008450 A MX 2011008450A MX 2011008450 A MX2011008450 A MX 2011008450A MX 2011008450 A MX2011008450 A MX 2011008450A
Authority
MX
Mexico
Prior art keywords
compounds
methods
agonists
antagonists
receptor
Prior art date
Application number
MX2011008450A
Other languages
English (en)
Inventor
Adrian D Hobson
Christopher M Harris
Noel S Wilson
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX2011008450A publication Critical patent/MX2011008450A/es

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    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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Abstract

Se describen compuestos que son agonistas o antagonistas del receptor S1P5, composiciones que comprenden dichos compuestos, y métodos para utilizar dichos compuestos y composiciones. En ciertas modalidades, dichos compuestos son derivados de ácido 1- bencilazetidin-3-carboxílico. En ciertas modalidades, dichos métodos se refieren al tratamiento de dolor neuropático y/o trastorno neurodegenerativo. En ciertas modalidades, dichos compuestos pueden ser utilizados en combinación con un segundo agente terapéutico.
MX2011008450A 2009-02-10 2010-02-10 Agonistas y antagonistas del receptor s1p5, y metodos de uso de los mismos. MX2011008450A (es)

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