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MX2010006397A - Compuestos heterociclicos antivirales. - Google Patents

Compuestos heterociclicos antivirales.

Info

Publication number
MX2010006397A
MX2010006397A MX2010006397A MX2010006397A MX2010006397A MX 2010006397 A MX2010006397 A MX 2010006397A MX 2010006397 A MX2010006397 A MX 2010006397A MX 2010006397 A MX2010006397 A MX 2010006397A MX 2010006397 A MX2010006397 A MX 2010006397A
Authority
MX
Mexico
Prior art keywords
treatment
antiviral compounds
hiv
heterocyclic antiviral
infections
Prior art date
Application number
MX2010006397A
Other languages
English (en)
Inventor
Zachary Kevin Sweeney
Roland J Billedeau
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40262294&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2010006397(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2010006397A publication Critical patent/MX2010006397A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Compuestos de fórmula (I), en donde R1, R2, R3, X1, X2 y Ar, las definidas en este documento o sales farmacéuticamente aceptable del mismo, inhiben el VIH-I de la transcriptasa inversa y proporciona un método para la prevención y tratamiento de infecciones de VIH-I y el tratamiento del SIDA y / o ARC. La presente invención se refiere también a composiciones que contienen compuestos de fórmula (I) útiles para la prevención y tratamiento de infecciones de VIH-I y el tratamiento del SIDA y / o ARC.
MX2010006397A 2007-12-21 2008-12-11 Compuestos heterociclicos antivirales. MX2010006397A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1614207P 2007-12-21 2007-12-21
PCT/EP2008/067274 WO2009080534A1 (en) 2007-12-21 2008-12-11 Heterocyclic antiviral compounds

Publications (1)

Publication Number Publication Date
MX2010006397A true MX2010006397A (es) 2010-07-05

Family

ID=40262294

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010006397A MX2010006397A (es) 2007-12-21 2008-12-11 Compuestos heterociclicos antivirales.

Country Status (18)

Country Link
US (1) US8063028B2 (es)
EP (1) EP2225239B1 (es)
JP (1) JP5411160B2 (es)
KR (2) KR101610415B1 (es)
CN (1) CN101903382B (es)
AR (1) AR069789A1 (es)
AU (1) AU2008340422B2 (es)
BR (1) BRPI0821349A2 (es)
CA (1) CA2709348C (es)
CL (1) CL2008003786A1 (es)
ES (1) ES2526649T3 (es)
IL (1) IL205863A (es)
MX (1) MX2010006397A (es)
PE (1) PE20091177A1 (es)
RU (1) RU2495878C2 (es)
TW (1) TWI445533B (es)
WO (1) WO2009080534A1 (es)
ZA (1) ZA201003815B (es)

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US20110053931A1 (en) * 2006-06-08 2011-03-03 John Gaudino Quinoline compounds and methods of use
DE102007026341A1 (de) 2007-06-06 2008-12-11 Merck Patent Gmbh Benzoxazolonderivate
DE102007032507A1 (de) 2007-07-12 2009-04-02 Merck Patent Gmbh Pyridazinonderivate
DE102007061963A1 (de) 2007-12-21 2009-06-25 Merck Patent Gmbh Pyridazinonderivate
DE102008019907A1 (de) 2008-04-21 2009-10-22 Merck Patent Gmbh Pyridazinonderivate
DE102008028905A1 (de) 2008-06-18 2009-12-24 Merck Patent Gmbh 3-(3-Pyrimidin-2-yl-benzyl)-[1,2,4]triazolo[4,3-b]pyridazinderivate
US8592448B2 (en) 2008-11-20 2013-11-26 OSI Pharmaceuticals, LLC Substituted pyrrolo[2,3-b]-pyridines and -pyrazines
DK2361250T3 (da) 2008-12-22 2013-11-04 Merck Patent Gmbh Nye polymorfe former af 6-(1-methyl-1h-pyrazol-4-yl)-2-{3-[5-(2-morpholin-4-yl-ethoxy)-pyrimidin-2-yl]-benzyl}-2h-pyridazin-3-on-dihydrogenphosphat og fremgangsmåder til fremstilling deraf
WO2011049988A2 (en) * 2009-10-20 2011-04-28 Eiger Biopharmaceuticals, Inc. Indazoles to treat flaviviridae virus infection
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AR081039A1 (es) 2010-05-14 2012-05-30 Osi Pharmaceuticals Llc Inhibidores biciclicos fusionados de quinasa
WO2011143646A1 (en) * 2010-05-14 2011-11-17 OSI Pharmaceuticals, LLC Fused bicyclic kinase inhibitors
US10872283B2 (en) 2018-10-31 2020-12-22 United Services Automobile Association (Usaa) Wireless communications device with concealed value
AR117169A1 (es) * 2018-11-28 2021-07-14 Bayer Ag (tio)amidas de piridazina como compuestos fungicidas
CN111153775B (zh) * 2020-01-16 2023-04-28 江苏理工学院 一种三氯生甲酯的制备方法

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Also Published As

Publication number Publication date
KR20150070440A (ko) 2015-06-24
ZA201003815B (en) 2011-02-23
CN101903382B (zh) 2012-11-28
KR20100095606A (ko) 2010-08-31
PE20091177A1 (es) 2009-08-03
IL205863A0 (en) 2010-11-30
US20090170856A1 (en) 2009-07-02
TWI445533B (zh) 2014-07-21
JP2011506535A (ja) 2011-03-03
CA2709348C (en) 2016-07-19
TW200930372A (en) 2009-07-16
EP2225239B1 (en) 2014-10-22
KR101610607B1 (ko) 2016-04-07
RU2495878C2 (ru) 2013-10-20
KR101610415B1 (ko) 2016-04-07
EP2225239A1 (en) 2010-09-08
WO2009080534A1 (en) 2009-07-02
IL205863A (en) 2016-08-31
CL2008003786A1 (es) 2010-02-19
RU2010129548A (ru) 2012-01-27
CA2709348A1 (en) 2009-07-02
ES2526649T3 (es) 2015-01-14
CN101903382A (zh) 2010-12-01
JP5411160B2 (ja) 2014-02-12
US8063028B2 (en) 2011-11-22
AU2008340422A1 (en) 2009-07-02
AU2008340422B2 (en) 2014-06-19
BRPI0821349A2 (pt) 2019-09-24
AR069789A1 (es) 2010-02-17

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