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MX2010005811A - Enumeracion automatica y caracterizacion de las celulas del melanoma circulantes en la sangre. - Google Patents

Enumeracion automatica y caracterizacion de las celulas del melanoma circulantes en la sangre.

Info

Publication number
MX2010005811A
MX2010005811A MX2010005811A MX2010005811A MX2010005811A MX 2010005811 A MX2010005811 A MX 2010005811A MX 2010005811 A MX2010005811 A MX 2010005811A MX 2010005811 A MX2010005811 A MX 2010005811A MX 2010005811 A MX2010005811 A MX 2010005811A
Authority
MX
Mexico
Prior art keywords
melanoma cells
blood
circulating melanoma
cells
circulating
Prior art date
Application number
MX2010005811A
Other languages
English (en)
Inventor
Mark Carle Connelly
Galla Chandra Rao
Leon Wmm Terstappen
Original Assignee
Veridex Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Veridex Llc filed Critical Veridex Llc
Publication of MX2010005811A publication Critical patent/MX2010005811A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/5743—Specifically defined cancers of skin, e.g. melanoma
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70589—CD45
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

El CellTracks(r) System proporciona un sistema para enumerar las células del melanoma circulantes en la sangre. El sistema concentra inmunomagnéticamente células epiteliales, etiqueta de manera fluorescente las células e identifica y cuantifica las células del melanoma circulantes. La cantidad absoluta de células del melanoma circulantes detectadas en la carga tumoral de la sangre periférica es, en parte, un factor para la predicción de la supervivencia, tiempo de progreso y respuesta a la terapia. El diagnóstico y el control del melanoma se ha limitado por la incapacidad para observar las células del melanoma circulantes. La presente invención proporciona un método de enumerar las células del melanoma circulante en muestras de sangre. Por consiguiente, esta tecnología suministra un medio y un dispositivo para controlar el progreso de la enfermedad en pacientes con melanoma.
MX2010005811A 2007-11-27 2008-10-20 Enumeracion automatica y caracterizacion de las celulas del melanoma circulantes en la sangre. MX2010005811A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US434507P 2007-11-27 2007-11-27
PCT/US2008/080436 WO2009070392A1 (en) 2007-11-27 2008-10-20 Automated enumeration and characterization of circulating melanoma cells in blood

Publications (1)

Publication Number Publication Date
MX2010005811A true MX2010005811A (es) 2010-06-09

Family

ID=40670042

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010005811A MX2010005811A (es) 2007-11-27 2008-10-20 Enumeracion automatica y caracterizacion de las celulas del melanoma circulantes en la sangre.

Country Status (11)

Country Link
US (1) US20090136946A1 (es)
EP (1) EP2225563B1 (es)
JP (1) JP5479355B2 (es)
KR (1) KR101604649B1 (es)
CN (1) CN101878429B (es)
BR (1) BRPI0819854B1 (es)
CA (1) CA2706442C (es)
DK (1) DK2225563T3 (es)
IL (1) IL205864A (es)
MX (1) MX2010005811A (es)
WO (1) WO2009070392A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010068812A1 (en) 2008-12-10 2010-06-17 Abqmr, Inc. Nuclear magnetic resonance apparatus, methods and associated technology
WO2010151109A1 (en) * 2009-06-26 2010-12-29 Erasmus University Medical Center Rotterdam Identifying circulating tumor cells (ctcs) using cd146 in breast cancers patients
US20110262989A1 (en) 2010-04-21 2011-10-27 Nanomr, Inc. Isolating a target analyte from a body fluid
US9476812B2 (en) 2010-04-21 2016-10-25 Dna Electronics, Inc. Methods for isolating a target analyte from a heterogeneous sample
US8841104B2 (en) 2010-04-21 2014-09-23 Nanomr, Inc. Methods for isolating a target analyte from a heterogeneous sample
US9428547B2 (en) 2010-04-21 2016-08-30 Dna Electronics, Inc. Compositions for isolating a target analyte from a heterogeneous sample
TWI539158B (zh) * 2010-06-08 2016-06-21 維里德克斯有限責任公司 使用血液中之循環黑色素瘤細胞預測黑色素瘤病患之臨床結果的方法。
PT2734307T (pt) * 2011-07-21 2020-06-25 Menarini Silicon Biosystems Spa Ensaio para capturar e detetar células circulantes de mieloma múltiplo do sangue
US9995742B2 (en) 2012-12-19 2018-06-12 Dnae Group Holdings Limited Sample entry
US9434940B2 (en) 2012-12-19 2016-09-06 Dna Electronics, Inc. Methods for universal target capture
US10000557B2 (en) 2012-12-19 2018-06-19 Dnae Group Holdings Limited Methods for raising antibodies
US9599610B2 (en) 2012-12-19 2017-03-21 Dnae Group Holdings Limited Target capture system
US9551704B2 (en) 2012-12-19 2017-01-24 Dna Electronics, Inc. Target detection
US9804069B2 (en) 2012-12-19 2017-10-31 Dnae Group Holdings Limited Methods for degrading nucleic acid
AU2014239168A1 (en) 2013-03-15 2015-10-29 Janssen Diagnostics, Llc Enrichment of circulating tumor cells by depleting white blood cells
CN103472227A (zh) * 2013-09-18 2013-12-25 上海卫恒医疗器械有限公司 一种循环肿瘤细胞检测试剂盒、配套仪器及应用
ES2765981T3 (es) 2015-05-26 2020-06-11 Creatv Microtech Inc Uso del índice mitótico de células tumorales circulantes en la estratificación y diagnóstico de cáncer

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
DE19736691A1 (de) * 1997-08-22 1999-02-25 Michael Prof Dr Med Giesing Verfahren zur Charakterisierung und Identifizierung disseminierter und metastasierter Krebszellen
JP2001523645A (ja) * 1997-11-14 2001-11-27 ザ・ゼネラル・ホスピタル・コーポレイション 血液学的疾患の処置
US20010018192A1 (en) * 1998-02-12 2001-08-30 Terstappen Leon W.M.M. Labeled cells for use as an internal functional control in rare cell detection assays
IL137802A0 (en) * 1998-02-12 2001-10-31 Immunivest Corp A method and kit for detecting rare cells in a mixed cell population
US7029652B2 (en) * 1998-09-16 2006-04-18 The Regents Of The University Of California Method of treating tumors
US6551843B1 (en) * 1999-01-29 2003-04-22 Immunivest Corporation Methods for enhancing binding interactions between members of specific binding pairs
US6222096B1 (en) * 1999-03-01 2001-04-24 Stine Biotechnology Promoter and construct for plant transformation
US6623982B1 (en) * 1999-07-12 2003-09-23 Immunivest Corporation Increased separation efficiency via controlled aggregation of magnetic nanoparticles
ATE488529T1 (de) * 1999-07-28 2010-12-15 Genentech Inc Zusammensetzungen und verfahren zur behandlung von tumoren
WO2001073133A1 (en) * 2000-03-27 2001-10-04 Thomas Jefferson University Compositions and methods for identifying and targeting cancer cells
JP2004523730A (ja) * 2000-10-13 2004-08-05 モナッシュ ユニバーシティ 胸腺機能診断用インジケーター
US7223596B2 (en) * 2003-09-05 2007-05-29 Wisconsin Alumni Research Foundation Malignant endothelial cell line and uses thereof in models for angiogenesis
US20070037173A1 (en) * 2005-08-12 2007-02-15 Allard Jeffrey W Circulating tumor cells (CTC's): early assessment of time to progression, survival and response to therapy in metastatic cancer patients
WO2006130737A1 (en) * 2005-06-02 2006-12-07 Immunivest Corporation A method for assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells

Also Published As

Publication number Publication date
KR20100101109A (ko) 2010-09-16
BRPI0819854A2 (pt) 2015-06-16
WO2009070392A1 (en) 2009-06-04
EP2225563A4 (en) 2011-11-16
KR101604649B1 (ko) 2016-03-18
CN101878429B (zh) 2015-05-20
JP2011505012A (ja) 2011-02-17
IL205864A (en) 2016-12-29
BRPI0819854B1 (pt) 2019-06-04
CA2706442A1 (en) 2009-06-04
HK1148068A1 (en) 2011-08-26
JP5479355B2 (ja) 2014-04-23
EP2225563B1 (en) 2015-01-21
US20090136946A1 (en) 2009-05-28
HK1148348A1 (en) 2011-09-02
CN101878429A (zh) 2010-11-03
EP2225563A1 (en) 2010-09-08
CA2706442C (en) 2017-07-11
DK2225563T3 (en) 2015-02-09
IL205864A0 (en) 2010-11-30

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