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MX2010004510A - Metodo para prevenir los efectos nocivos de peptido 1 tipo glucagon (glp-1). - Google Patents

Metodo para prevenir los efectos nocivos de peptido 1 tipo glucagon (glp-1).

Info

Publication number
MX2010004510A
MX2010004510A MX2010004510A MX2010004510A MX2010004510A MX 2010004510 A MX2010004510 A MX 2010004510A MX 2010004510 A MX2010004510 A MX 2010004510A MX 2010004510 A MX2010004510 A MX 2010004510A MX 2010004510 A MX2010004510 A MX 2010004510A
Authority
MX
Mexico
Prior art keywords
glp
adverse effects
preventing adverse
preventing
pulmonary
Prior art date
Application number
MX2010004510A
Other languages
English (en)
Inventor
Peter Richardson
Donald Costello
Robert A Baughman
Original Assignee
Mannkind Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mannkind Corp filed Critical Mannkind Corp
Publication of MX2010004510A publication Critical patent/MX2010004510A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describe un método para prevenir o reducir efectos adversos tal como sudoración en exceso, nausea y vómito, los que normalmente son relacionados con administración subcutánea e intravenosa de terapia de péptido similar a glucagon 1 (GLP-1). En particular, el método comprende la rápida administración de una formulación GLP-1 en la circulación pulmonar tal como la inhalación, directamente en las capilares alveolares pulmonares utilizando un sistema de suministro de fármaco en polvo seco.
MX2010004510A 2007-10-24 2008-10-24 Metodo para prevenir los efectos nocivos de peptido 1 tipo glucagon (glp-1). MX2010004510A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US98236807P 2007-10-24 2007-10-24
US98562007P 2007-11-05 2007-11-05
US3374008P 2008-03-04 2008-03-04
US5212708P 2008-05-09 2008-05-09
PCT/US2008/081218 WO2009055740A2 (en) 2007-10-24 2008-10-24 Method of preventing adverse effects by glp-1

Publications (1)

Publication Number Publication Date
MX2010004510A true MX2010004510A (es) 2010-07-02

Family

ID=40546046

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010004510A MX2010004510A (es) 2007-10-24 2008-10-24 Metodo para prevenir los efectos nocivos de peptido 1 tipo glucagon (glp-1).

Country Status (15)

Country Link
US (4) US8377869B2 (es)
EP (2) EP2954893A1 (es)
JP (2) JP2011500850A (es)
KR (2) KR101736535B1 (es)
CN (1) CN101969927A (es)
AU (2) AU2008316634B2 (es)
BR (1) BRPI0818872A2 (es)
CA (1) CA2703338A1 (es)
DK (1) DK2211842T3 (es)
ES (1) ES2547529T3 (es)
HU (1) HUE025485T2 (es)
MX (1) MX2010004510A (es)
PL (1) PL2211842T3 (es)
RU (2) RU2474415C2 (es)
WO (1) WO2009055740A2 (es)

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AU2014202731A1 (en) 2014-06-12
KR101736502B1 (ko) 2017-05-16
KR101736535B1 (ko) 2017-05-16
CN101969927A (zh) 2011-02-09
EP2211842B1 (en) 2015-08-12
JP2015013892A (ja) 2015-01-22
CA2703338A1 (en) 2009-04-30
KR20130123467A (ko) 2013-11-12
US8377869B2 (en) 2013-02-19
ES2547529T3 (es) 2015-10-07
EP2954893A1 (en) 2015-12-16
RU2012146344A (ru) 2014-05-10
US20090110647A1 (en) 2009-04-30
RU2474415C2 (ru) 2013-02-10
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RU2010120666A (ru) 2011-11-27
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DK2211842T3 (en) 2015-09-21
AU2008316634A1 (en) 2009-04-30
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WO2009055740A3 (en) 2009-06-11
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US20130125886A1 (en) 2013-05-23

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