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MX2010001370A - Composiciones que comprenden agonista del receptor glucocorticoide disociado para tratar o controlar inflamacion del segmento anterior. - Google Patents

Composiciones que comprenden agonista del receptor glucocorticoide disociado para tratar o controlar inflamacion del segmento anterior.

Info

Publication number
MX2010001370A
MX2010001370A MX2010001370A MX2010001370A MX2010001370A MX 2010001370 A MX2010001370 A MX 2010001370A MX 2010001370 A MX2010001370 A MX 2010001370A MX 2010001370 A MX2010001370 A MX 2010001370A MX 2010001370 A MX2010001370 A MX 2010001370A
Authority
MX
Mexico
Prior art keywords
treating
receptor agonist
glucocorticoid receptor
compositions
anterior
Prior art date
Application number
MX2010001370A
Other languages
English (en)
Inventor
Keith Wayne Ward
Claudio Bucolo
Original Assignee
Bausch & Lomb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb filed Critical Bausch & Lomb
Publication of MX2010001370A publication Critical patent/MX2010001370A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Se describe una composición para tratar o controlar una enfermedad o afección inflamatoria del segmento anterior, que comprende un agonista del receptor de glucocorticoide disociado ('DIGRA'). La composición puede incluir opcionalmente un agente anti-inflamatorio, un agente anti-infeccioso, o ambos. La composición puede ser formulada para aplicación tópica, inyección, o implantación en la porción anterior del ojo o un tejido adyacente a éste.
MX2010001370A 2007-08-10 2008-08-05 Composiciones que comprenden agonista del receptor glucocorticoide disociado para tratar o controlar inflamacion del segmento anterior. MX2010001370A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95504407P 2007-08-10 2007-08-10
PCT/US2008/072201 WO2009023471A2 (en) 2007-08-10 2008-08-05 Compositions comprising a dissociated glucocorticoid receptor agonist for treating or controlling anterior-segment inflammation

Publications (1)

Publication Number Publication Date
MX2010001370A true MX2010001370A (es) 2010-03-01

Family

ID=40263555

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010001370A MX2010001370A (es) 2007-08-10 2008-08-05 Composiciones que comprenden agonista del receptor glucocorticoide disociado para tratar o controlar inflamacion del segmento anterior.

Country Status (18)

Country Link
US (1) US20090042936A1 (es)
EP (1) EP2190431B1 (es)
JP (1) JP5209718B2 (es)
KR (2) KR20120113802A (es)
CN (1) CN101969950A (es)
AU (1) AU2008287142B2 (es)
BR (1) BRPI0815130A2 (es)
CA (1) CA2694227C (es)
CY (1) CY1114480T1 (es)
DK (1) DK2190431T3 (es)
ES (1) ES2421405T3 (es)
HR (1) HRP20130631T1 (es)
MX (1) MX2010001370A (es)
PL (1) PL2190431T3 (es)
PT (1) PT2190431E (es)
SI (1) SI2190431T1 (es)
TW (1) TWI410252B (es)
WO (1) WO2009023471A2 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110077270A1 (en) * 2009-04-21 2011-03-31 Pfeffer Bruce A Compositions and Methods for Treating Ocular Inflammation with Lower Risk of Increased Intraocular Pressure
US10278810B2 (en) * 2010-04-29 2019-05-07 Ojo, Llc Injectable physiologically adaptive intraocular lenses (IOL's)
US20120316199A1 (en) * 2011-06-07 2012-12-13 Ward Keith W Compositions and methods for treating, controlling, reducing, or ameliorating inflammatory pain
ES2727474T3 (es) * 2012-05-08 2019-10-16 Nicox Ophthalmics Inc Nanocristales de propionato de fluticasona
EP3914249B1 (en) 2019-01-22 2024-05-01 Akribes Biomedical GmbH Selective glucocorticoid receptor modifiers for treating impaired skin wound healing
WO2020215084A1 (en) * 2019-04-18 2020-10-22 Teeny Clean, Llc Device and method for stimulating the meibomian glands of the eyelid

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* Cited by examiner, † Cited by third party
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JP2613139B2 (ja) * 1990-07-19 1997-05-21 エスエス製薬 株式会社 キノロンカルボン酸誘導体
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US6051576A (en) * 1994-01-28 2000-04-18 University Of Kentucky Research Foundation Means to achieve sustained release of synergistic drugs by conjugation
US5773019A (en) * 1995-09-27 1998-06-30 The University Of Kentucky Research Foundation Implantable controlled release device to deliver drugs directly to an internal portion of the body
US5902598A (en) * 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
US6242196B1 (en) * 1997-12-11 2001-06-05 Dana-Farber Cancer Institute Methods and pharmaceutical compositions for inhibiting tumor cell growth
WO2000000194A1 (en) * 1998-06-27 2000-01-06 Photogenesis, Inc. Ophthalmic uses of ppargamma agonists and ppargamma antagonists
WO2000018404A1 (en) * 1998-09-30 2000-04-06 Alcon Laboratories, Inc. Antibiotic compositions for treatment of the eye, ear and nose
US6726918B1 (en) * 2000-07-05 2004-04-27 Oculex Pharmaceuticals, Inc. Methods for treating inflammation-mediated conditions of the eye
WO2003059899A1 (en) * 2002-01-14 2003-07-24 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical formulations containing them and uses thereof
US7268152B2 (en) * 2002-03-26 2007-09-11 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
WO2003082280A1 (en) * 2002-03-26 2003-10-09 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US6897224B2 (en) * 2002-04-02 2005-05-24 Schering Ag Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors
US7074806B2 (en) * 2002-06-06 2006-07-11 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
SI1521733T1 (sl) * 2002-07-08 2014-10-30 Pfizer Products Inc. Modulatorji glukokortikoidnega receptorja
US7579469B2 (en) * 2003-01-03 2009-08-25 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US20040224992A1 (en) * 2003-02-27 2004-11-11 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
WO2004097410A1 (en) * 2003-04-30 2004-11-11 Pfizer Products Inc. Screening methods for cataractogenic risk
UY28526A1 (es) * 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
US7795272B2 (en) * 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
EP1730145A1 (en) * 2004-03-22 2006-12-13 Boehringer Ingelheim Pharmaceuticals Inc. Alpha-trifluoromethyl alcohols or amines as glucocorticoid mimetics
US7417056B2 (en) * 2004-11-12 2008-08-26 Schering Ag 5-substituted quinoline and isoquinoline derivatives, a process for their production and their use as anti-inflammatory agents
DE102004055633A1 (de) * 2004-11-12 2006-05-18 Schering Ag 5-substituierte Chinolin- und Isochinolin-Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
CA2592514A1 (en) * 2004-12-27 2006-07-06 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
CN102229562B (zh) * 2005-09-14 2013-11-13 参天制药株式会社 具有糖皮质激素受体结合活性的1,2-二氢喹啉衍生物
PL2049112T3 (pl) * 2006-08-07 2012-07-31 Bausch & Lomb Leczenie infekcji i ich następstw za pomocą połączonych zdysocjowanych agonistów receptora glukokortykoidowego i środków przeciwzapalnych
PT2051710E (pt) * 2006-08-07 2012-02-08 Bausch & Lomb Composições e métodos para tratar, reduzir, melhorar ou aliviar doenças oftálmicas do segmento posterior
SI2056799T1 (sl) * 2006-08-31 2013-11-29 Bausch & Lomb Incorporated Sestavki in postopki za zdravljenje ali preprečevanje glavkoma ali njegovega napredovanja
WO2008146871A1 (ja) * 2007-05-29 2008-12-04 Santen Pharmaceutical Co., Ltd. グルココルチコイド受容体結合活性を有する、スルホン酸エステル又はスルホン酸アミド構造を導入したフェニル基を置換基として有する新規１，２，３，４－テトラヒドロキノキサリン誘導体
WO2008154129A1 (en) * 2007-06-08 2008-12-18 Bausch & Lomb Incorporated Pharmaceutical compositions and method for treating, reducing, ameliorating, alleviating, or preventing dry eye

Also Published As

Publication number Publication date
WO2009023471A2 (en) 2009-02-19
KR20120113802A (ko) 2012-10-15
SI2190431T1 (sl) 2013-10-30
HRP20130631T1 (hr) 2013-08-31
KR20100029851A (ko) 2010-03-17
AU2008287142B2 (en) 2012-02-02
US20090042936A1 (en) 2009-02-12
DK2190431T3 (da) 2013-09-08
BRPI0815130A2 (pt) 2017-05-09
HK1141249A1 (en) 2010-11-05
PT2190431E (pt) 2013-10-09
CA2694227C (en) 2012-07-03
CN101969950A (zh) 2011-02-09
ES2421405T3 (es) 2013-09-02
PL2190431T3 (pl) 2013-11-29
EP2190431A2 (en) 2010-06-02
JP5209718B2 (ja) 2013-06-12
WO2009023471A3 (en) 2009-06-25
CA2694227A1 (en) 2009-02-19
TW200911286A (en) 2009-03-16
JP2010535796A (ja) 2010-11-25
EP2190431B1 (en) 2013-07-03
KR101298826B1 (ko) 2013-08-27
CY1114480T1 (el) 2016-10-05
TWI410252B (zh) 2013-10-01
AU2008287142A1 (en) 2009-02-19

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