[go: up one dir, main page]

MX2009013819A - Señales paracrinas a partir de celulas alimentadoras mesenquimatosas y regulacion de la expansion y diferenciacion de progenitores hepaticos usando las mismas. - Google Patents

Señales paracrinas a partir de celulas alimentadoras mesenquimatosas y regulacion de la expansion y diferenciacion de progenitores hepaticos usando las mismas.

Info

Publication number
MX2009013819A
MX2009013819A MX2009013819A MX2009013819A MX2009013819A MX 2009013819 A MX2009013819 A MX 2009013819A MX 2009013819 A MX2009013819 A MX 2009013819A MX 2009013819 A MX2009013819 A MX 2009013819A MX 2009013819 A MX2009013819 A MX 2009013819A
Authority
MX
Mexico
Prior art keywords
differentiation
feeder cells
same
hepatic progenitors
paracrine signals
Prior art date
Application number
MX2009013819A
Other languages
English (en)
Inventor
Lola M Reid
Randall E Mcclelland
Joshua Uronis
Hsin-Iei Yao
Eliane Wauthier
Original Assignee
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina filed Critical Univ North Carolina
Publication of MX2009013819A publication Critical patent/MX2009013819A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/80—Hyaluronan

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Se provee un método para controlar la supervivencia, proliferación y/o diferenciación de progenitores hepáticos in vitro al utilizar tipos específicos de células alimentadoras mesenquimales o una o más de las señales parocrinas producidas por esos alimentadores.
MX2009013819A 2007-06-15 2008-06-13 Señales paracrinas a partir de celulas alimentadoras mesenquimatosas y regulacion de la expansion y diferenciacion de progenitores hepaticos usando las mismas. MX2009013819A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94443507P 2007-06-15 2007-06-15
PCT/US2008/007397 WO2008156667A1 (en) 2007-06-15 2008-06-13 Paracrine signals from mesenchymal feeder cells and regulating expansion and differentiation of hepatic progenitors using same

Publications (1)

Publication Number Publication Date
MX2009013819A true MX2009013819A (es) 2010-05-17

Family

ID=40136896

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009013819A MX2009013819A (es) 2007-06-15 2008-06-13 Señales paracrinas a partir de celulas alimentadoras mesenquimatosas y regulacion de la expansion y diferenciacion de progenitores hepaticos usando las mismas.

Country Status (13)

Country Link
US (2) US20080318316A1 (es)
EP (1) EP2171040A4 (es)
JP (1) JP2010529855A (es)
KR (1) KR20100094970A (es)
CN (1) CN101868533A (es)
AU (1) AU2008266992A1 (es)
BR (1) BRPI0813353A2 (es)
CA (1) CA2727535A1 (es)
IL (1) IL202738A0 (es)
IN (1) IN2010KN00157A (es)
MX (1) MX2009013819A (es)
TW (1) TW200916581A (es)
WO (1) WO2008156667A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070269412A1 (en) * 2003-12-02 2007-11-22 Celavie Biosciences, Llc Pluripotent cells
US20100209399A1 (en) * 2009-02-13 2010-08-19 Celavie Biosciences, Llc Brain-derived stem cells for repair of musculoskeletal system in vertebrate subjects
CN105456292B (zh) * 2009-10-30 2019-03-26 北卡罗来纳大学教堂山分校 来自肝外胆管树的专能干细胞及其分离方法
TW201202424A (en) * 2010-05-07 2012-01-16 Univ North Carolina Method of engrafting cells from solid tissues
ITMI20120896A1 (it) * 2012-05-23 2013-11-24 Bongulielmi Reto Condroitina per uso in medicina
EP2917337B1 (en) 2012-11-08 2020-01-08 InGeneron Inc. Media for culturing, preserving, and administering regenerative cells
US9533013B2 (en) 2013-03-13 2017-01-03 University Of North Carolina At Chapel Hill Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree
US11066649B2 (en) 2014-03-19 2021-07-20 Institut National De La Sante Et De La Recherche Medicale (Inserm) Method for inducing human cholangiocyte differentiation
WO2016010082A1 (ja) * 2014-07-16 2016-01-21 国立大学法人大阪大学 ラミニンフラグメントの細胞培養基質活性増強方法
CN108431209B (zh) * 2015-06-12 2023-02-10 新加坡科技研究局 肝脏干细胞的衍生和成熟肝细胞类型及其用途
US20170369849A1 (en) 2016-05-11 2017-12-28 The University Of North Carolina At Chapel Hill Compositions and methods for bioengineered tissues
JP2020505076A (ja) * 2017-02-01 2020-02-20 フェニックスソングス バイオロジカルズ，インコーポレイテッド 肝細胞の共培養を含む組成物および方法
EP3684386A4 (en) * 2017-09-22 2021-06-30 Lifenet Health PLATE HEPATOCYTES AND THE PREPARATION AND USES OF THEM
US20210395681A1 (en) * 2018-10-11 2021-12-23 Ichimaru Pharcos Co., Ltd. Culture medium for growth of neural stem cells

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6069005A (en) * 1991-08-07 2000-05-30 Albert Einstein College Of Medicine Of Yeshwa University Hapatoblasts and method of isolating same
EP0597964A4 (en) * 1991-08-07 1994-11-30 Einstein Coll Med PROLIFERATION OF HEPATOCYTE PRECURSORS.
ATE414143T1 (de) * 1999-01-19 2008-11-15 Univ North Carolina Menschliche leber-vorläuferzellen
US7456017B2 (en) * 1999-10-01 2008-11-25 University Of North Carolina At Chapel Hill Processes for clonal growth of hepatic progenitor cells
US7413897B2 (en) * 2002-03-15 2008-08-19 University Of North Carolina At Chapel Hill Primitive and proximal hepatic stem cells
CA2630355A1 (en) * 2005-11-16 2007-05-24 University Of North Carolina At Chapel Hill Extracellular matrix components for expansion or differentiation of hepatic progenitors
CN101600791A (zh) * 2006-06-28 2009-12-09 维斯塔治疗公司 分离肝祖细胞的基质和方法
CA2680254A1 (en) * 2007-03-06 2008-09-12 University Of North Carolina At Chapel Hill Complexes of hyaluronans, other matrix components, hormones and growth factors for maintenance, expansion and/or differentiation of hepatic cells

Also Published As

Publication number Publication date
IN2010KN00157A (es) 2015-08-28
BRPI0813353A2 (pt) 2014-10-14
CN101868533A (zh) 2010-10-20
AU2008266992A1 (en) 2008-12-24
EP2171040A4 (en) 2010-08-04
EP2171040A1 (en) 2010-04-07
TW200916581A (en) 2009-04-16
US20080318316A1 (en) 2008-12-25
JP2010529855A (ja) 2010-09-02
WO2008156667A1 (en) 2008-12-24
IL202738A0 (en) 2011-08-01
KR20100094970A (ko) 2010-08-27
US20110065188A1 (en) 2011-03-17
CA2727535A1 (en) 2008-12-24
US8404483B2 (en) 2013-03-26

Similar Documents

Publication Publication Date Title
MX2009013819A (es) Señales paracrinas a partir de celulas alimentadoras mesenquimatosas y regulacion de la expansion y diferenciacion de progenitores hepaticos usando las mismas.
EP2410044A3 (en) Stem cells culture systems
AU2019268194A1 (en) Cell culture system
EP2343362B8 (en) Improved process for the culturing of cells
MY170749A (en) Increasing methionine yield
CA3147112C (en) ENDOCRINE PRECURSOR CELLS, PANCREATIC HORMONE-EXPRESSING CELLS, AND ASSOCIATED PRODUCTION PROCESSES
IL163180A (en) Growing populations of renewable hematopoietic stem cells and their methods
MY159971A (en) Multipotent/pluripotent cells and methods
WO2006030442A3 (en) Methods of ex vivo progenitor and stem cell expansion by co-culture with mesenchymal cells
SG196838A1 (en) Gpr120 receptor agonists and uses thereof
WO2007016566A3 (en) Production of reprogrammed cells with restored potential
MX2009011255A (es) Proceso para preparar capecitabina.
WO2012003479A3 (en) Methods for culturing undifferentiated cells using sustained release compositions
WO2010111659A8 (en) Tumor-initiating cells and methods for using same
TW200713716A (en) A power adapter including peripheral unit capable of supplying power for computer and the peripheral unit
GB2463834A (en) Viewing of feeds
EP1698690A4 (en) BASE MEDIUM FOR CULTIVATING ES CELLS
WO2005094353A3 (en) Methods for production of regulatory t cells and uses thereof
GB2451363A (en) Highly responsive master-slave valve positioning
GB2450599A (en) Automated culture of stem cells
EP1725656A4 (en) SERUM-FREE SUSPENSION CULTURE SYSTEM FOR MESENCHYM PRECURSOR CELLS
WO2006127706A3 (en) Method and system of configuring media units
MY158907A (en) Metabolites in animal feed
WO2009057313A1 (ja) 内皮前駆細胞（ｅｐｃ）の増殖・分化誘導方法
SG148168A1 (en) Genetically modified microorganism and process for production of macrolide compound using the microorganism

Legal Events

Date Code Title Description
FA Abandonment or withdrawal