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MX2009013336A - Sintesis de 3-aminopirazoles sustituidos. - Google Patents

Sintesis de 3-aminopirazoles sustituidos.

Info

Publication number
MX2009013336A
MX2009013336A MX2009013336A MX2009013336A MX2009013336A MX 2009013336 A MX2009013336 A MX 2009013336A MX 2009013336 A MX2009013336 A MX 2009013336A MX 2009013336 A MX2009013336 A MX 2009013336A MX 2009013336 A MX2009013336 A MX 2009013336A
Authority
MX
Mexico
Prior art keywords
aminopyrazoles
synthesis
substituted
formula
compound
Prior art date
Application number
MX2009013336A
Other languages
English (en)
Inventor
Marc A Labroli
Carmen S Alvarez
Timothy J Guzi
Kamil Paruch
Michael P Dwyer
Kartik M Keertikar
Cory Seth Poker
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MX2009013336A publication Critical patent/MX2009013336A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención describe un procedimiento para preparar el compuesto de la fórmula I: (ver fórmula (I)) en donde A, M y Z son como se define aquí; un ejemplo de un compuesto de la fórmula I es 3-amino-1-metil-1H-1´H-4,4´-bispirazol.
MX2009013336A 2007-06-07 2008-06-04 Sintesis de 3-aminopirazoles sustituidos. MX2009013336A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94255807P 2007-06-07 2007-06-07
PCT/US2008/007009 WO2008153870A1 (en) 2007-06-07 2008-06-04 Synthesis of substituted-3-aminopyrazoles

Publications (1)

Publication Number Publication Date
MX2009013336A true MX2009013336A (es) 2010-01-20

Family

ID=39735391

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009013336A MX2009013336A (es) 2007-06-07 2008-06-04 Sintesis de 3-aminopirazoles sustituidos.

Country Status (6)

Country Link
US (1) US20120029204A1 (es)
EP (1) EP2155725A1 (es)
JP (1) JP5198562B2 (es)
CA (1) CA2689667A1 (es)
MX (1) MX2009013336A (es)
WO (1) WO2008153870A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104151334A (zh) * 2014-07-04 2014-11-19 段晶晶 一种手性单螺旋配位聚合物及其制备方法
CN104311583A (zh) * 2014-11-22 2015-01-28 刘国政 基于柔性含氮和羧酸双配体的含锌化合物及其制备方法
JP7003109B2 (ja) * 2016-04-11 2022-02-21 エージェンシー フォー サイエンス， テクノロジー アンド リサーチ 化合物誘発性肝臓傷害を正確に予測するためのハイスループット方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL354982A1 (en) * 1999-09-30 2004-03-22 Neurogen Corporation Amino substituted pyrazolo[1,5,-a]-1,5-pyrimidines and pyrazolo[1,5-a]-1,3,5-triazines
US7196078B2 (en) * 2002-09-04 2007-03-27 Schering Corpoartion Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors
NZ539162A (en) * 2002-09-04 2006-07-28 Schering Corp Pyrazolopyrimidines as cyclin dependent kinase inhibitors
US7872014B2 (en) * 2003-07-23 2011-01-18 Exelixis, Inc. Anaplastic lymphoma kinase modulators and methods of use
AR049769A1 (es) * 2004-01-22 2006-09-06 Novartis Ag Derivados de pirazolo(1,5-a)pirimidin 7-il-amina para utilizarse en el tratamiento de enfermedades dependientes de la quinasa de proteina
TWI421078B (zh) * 2005-10-06 2014-01-01 Merck Sharp & Dohme 關卡激酶抑制劑及其用途

Also Published As

Publication number Publication date
JP2010529123A (ja) 2010-08-26
JP5198562B2 (ja) 2013-05-15
CA2689667A1 (en) 2008-12-18
US20120029204A1 (en) 2012-02-02
WO2008153870A1 (en) 2008-12-18
EP2155725A1 (en) 2010-02-24

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Legal Events

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