MX2009011865A - Tratamiento de lesiones viralmente inducidas. - Google Patents
Tratamiento de lesiones viralmente inducidas.Info
- Publication number
- MX2009011865A MX2009011865A MX2009011865A MX2009011865A MX2009011865A MX 2009011865 A MX2009011865 A MX 2009011865A MX 2009011865 A MX2009011865 A MX 2009011865A MX 2009011865 A MX2009011865 A MX 2009011865A MX 2009011865 A MX2009011865 A MX 2009011865A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- lesions
- papilloma virus
- virally induced
- induced lesions
- Prior art date
Links
- 230000003902 lesion Effects 0.000 title abstract 4
- 241001631646 Papillomaviridae Species 0.000 abstract 2
- VEBVPUXQAPLADL-POYOOMFHSA-N ingenol Chemical class C1=C(CO)[C@@H](O)[C@]2(O)[C@@H](O)C(C)=C[C@]32[C@H](C)C[C@H]2C(C)(C)[C@H]2[C@H]1C3=O VEBVPUXQAPLADL-POYOOMFHSA-N 0.000 abstract 2
- 241000701806 Human papillomavirus Species 0.000 abstract 1
- VEBVPUXQAPLADL-UHFFFAOYSA-N Ingenol Natural products C1=C(CO)C(O)C2(O)C(O)C(C)=CC32C(C)CC2C(C)(C)C2C1C3=O VEBVPUXQAPLADL-UHFFFAOYSA-N 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- -1 ingenol angelates Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
La presente invención se refiere en general al tratamiento de lesiones cutáneas que contienen células infectadas a través de un virus, así como a composiciones para el tratamiento de tales lesiones. Más específicamente, la invención se refiere al uso de compuestos de ingenol, particularmente angelatos de ingenol, para tratar lesiones causadas por infección con un virus de papiloma, tal como un virus de papiloma de mamífero, en particular un virus de Papiloma Humano.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2007902266A AU2007902266A0 (en) | 2007-04-30 | Treatment of virally induced lesions | |
| PCT/AU2008/000596 WO2008131491A1 (en) | 2007-04-30 | 2008-04-30 | Treatment of virally induced lesions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009011865A true MX2009011865A (es) | 2009-12-04 |
Family
ID=39925109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009011865A MX2009011865A (es) | 2007-04-30 | 2008-04-30 | Tratamiento de lesiones viralmente inducidas. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9895334B2 (es) |
| EP (1) | EP2152261B1 (es) |
| JP (1) | JP5497629B2 (es) |
| KR (1) | KR101485883B1 (es) |
| CN (1) | CN101742996B (es) |
| AU (1) | AU2008243705B2 (es) |
| BR (1) | BRPI0810806A2 (es) |
| CA (1) | CA2685473C (es) |
| CY (1) | CY1119269T1 (es) |
| DK (1) | DK2152261T3 (es) |
| ES (1) | ES2564173T3 (es) |
| HR (1) | HRP20160181T1 (es) |
| HU (1) | HUE028713T2 (es) |
| IL (1) | IL201796A (es) |
| MX (1) | MX2009011865A (es) |
| MY (1) | MY154484A (es) |
| NZ (1) | NZ580702A (es) |
| PL (1) | PL2152261T3 (es) |
| RU (1) | RU2506951C2 (es) |
| SI (1) | SI2152261T1 (es) |
| UA (1) | UA98328C2 (es) |
| WO (1) | WO2008131491A1 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ801700A0 (en) | 2000-06-07 | 2000-06-29 | Peplin Research Pty Ltd | Enzyme and viral activation |
| CA2589992C (en) | 2004-12-13 | 2014-04-22 | Peplin Research Pty Ltd | Treatment of solid cancers |
| US9895334B2 (en) | 2007-04-30 | 2018-02-20 | Leo Laboratories Limited | Treatment of virally induced lesions |
| ES2633755T3 (es) | 2009-02-13 | 2017-09-25 | Leo Laboratories Limited | Tratamiento de la piel |
| WO2011128780A1 (en) | 2010-04-16 | 2011-10-20 | Leo Pharma A/S | Crystalline ingenol mebutate |
| US9402823B2 (en) | 2010-12-17 | 2016-08-02 | Leo Laboratories Limited | Ingenols for treating seborrheic keratosis |
| TWI548616B (zh) * | 2010-12-22 | 2016-09-11 | 理奧實驗有限公司 | 巨大戟萜醇-3-醯化物iii及巨大戟萜醇-3-胺基甲酸酯化物 |
| US9388124B2 (en) | 2010-12-22 | 2016-07-12 | Leo Laboratories Limited | Ingenol-3-acylates I |
| US9656945B2 (en) | 2010-12-22 | 2017-05-23 | Leo Laboratories Limited | 3-acyl-ingenols II |
| WO2012176015A1 (en) | 2011-06-24 | 2012-12-27 | Leo Pharma A/S | Methods for treating uv-damaged skin and scc tumors and for removing tattoos with topical ingenol mebutate |
| KR101406201B1 (ko) * | 2011-10-19 | 2014-06-12 | 한국생명공학연구원 | 인제난 타입의 디테르펜 화합물 및 이를 포함하는 바이러스 감염 질환의 치료 또는 예방용 약학적 조성물 |
| CN104136081B (zh) * | 2012-03-02 | 2018-05-15 | 阿马佐尼亚菲托药品有限公司 | 再活化潜伏hiv病毒的巨大戟二萜醇衍生物 |
| US20130251782A1 (en) * | 2012-03-22 | 2013-09-26 | Leo Laboratories Limited | Topical application of ingenol mebutate with occlusion |
| IN2014DN11023A (es) * | 2012-06-26 | 2015-09-25 | Leo Lab Ltd | |
| GB201222406D0 (en) * | 2012-12-12 | 2013-01-23 | Leo Lab Ltd | Gel compositions |
| GB201222405D0 (en) * | 2012-12-12 | 2013-01-23 | Leo Lab Ltd | Gel compositions |
| US20150320679A1 (en) * | 2012-12-12 | 2015-11-12 | Leo Laboratories Limited | Gel compositions |
| GB201222403D0 (en) * | 2012-12-12 | 2013-01-23 | Leo Lab Ltd | Gel compositions |
| EP3007676A1 (en) * | 2013-06-12 | 2016-04-20 | Leo Laboratories Limited | A topical composition |
| KR101520428B1 (ko) * | 2013-11-22 | 2015-05-14 | 충남대학교산학협력단 | 대극 추출물을 유효성분으로 포함하는 항인플루엔자용 조성물 |
| CN104188979B (zh) * | 2014-08-11 | 2017-01-11 | 泰州祥泰康华医药科技有限公司 | 闭花木酮Cleistanone的O-(吗啉基)乙基衍生物在制备治疗缺血性脑损伤药物中的应用 |
| CN104523705A (zh) * | 2014-12-10 | 2015-04-22 | 南京大学 | 闭花木酮的o-(咪唑基)乙基衍生物在制备抗病毒药物中的应用 |
| US10722484B2 (en) | 2016-03-09 | 2020-07-28 | K-Gen, Inc. | Methods of cancer treatment |
| JP7495679B2 (ja) * | 2019-10-03 | 2024-06-05 | 国立大学法人京都大学 | ヒトパピローマウイルス性疣贅に対する貼付剤 |
| EP3915549A1 (en) * | 2020-05-26 | 2021-12-01 | Merck Patent GmbH | Senescence inducers for use in the treatment and/or prevention of virus induced diseases |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5804203A (en) * | 1994-12-21 | 1998-09-08 | Cosmederm Technologies | Topical product formulations containing strontium for reducing skin irritation |
| RU2174396C2 (ru) * | 1997-03-20 | 2001-10-10 | Панацея Биотек Лтд. | Фармацевтическая композиция для подавления и лечения аноректальных и ободочно-кишечных болезней |
| AUPQ801700A0 (en) | 2000-06-07 | 2000-06-29 | Peplin Research Pty Ltd | Enzyme and viral activation |
| CA2589992C (en) | 2004-12-13 | 2014-04-22 | Peplin Research Pty Ltd | Treatment of solid cancers |
| EP1951221A1 (en) * | 2005-11-14 | 2008-08-06 | Peplin Research Pty Ltd. | Use of angeloyl-substituted ingenanes in combination with other agents to treat cancer |
| GB0525680D0 (en) * | 2005-12-16 | 2006-01-25 | Peplin Ltd | Therapeutic compositions |
| US9895334B2 (en) | 2007-04-30 | 2018-02-20 | Leo Laboratories Limited | Treatment of virally induced lesions |
-
2008
- 2008-04-30 US US12/598,102 patent/US9895334B2/en not_active Expired - Fee Related
- 2008-04-30 WO PCT/AU2008/000596 patent/WO2008131491A1/en not_active Ceased
- 2008-04-30 SI SI200831581A patent/SI2152261T1/sl unknown
- 2008-04-30 ES ES08733422.3T patent/ES2564173T3/es active Active
- 2008-04-30 KR KR1020097024861A patent/KR101485883B1/ko not_active Expired - Fee Related
- 2008-04-30 EP EP08733422.3A patent/EP2152261B1/en active Active
- 2008-04-30 HU HUE08733422A patent/HUE028713T2/en unknown
- 2008-04-30 MX MX2009011865A patent/MX2009011865A/es active IP Right Grant
- 2008-04-30 CA CA2685473A patent/CA2685473C/en not_active Expired - Fee Related
- 2008-04-30 BR BRPI0810806-4A2A patent/BRPI0810806A2/pt active Search and Examination
- 2008-04-30 AU AU2008243705A patent/AU2008243705B2/en not_active Ceased
- 2008-04-30 DK DK08733422.3T patent/DK2152261T3/en active
- 2008-04-30 HR HRP20160181TT patent/HRP20160181T1/hr unknown
- 2008-04-30 JP JP2010504384A patent/JP5497629B2/ja not_active Expired - Fee Related
- 2008-04-30 CN CN2008800196132A patent/CN101742996B/zh not_active Expired - Fee Related
- 2008-04-30 NZ NZ580702A patent/NZ580702A/en not_active IP Right Cessation
- 2008-04-30 MY MYPI20094567A patent/MY154484A/en unknown
- 2008-04-30 PL PL08733422T patent/PL2152261T3/pl unknown
- 2008-04-30 RU RU2009144100/15A patent/RU2506951C2/ru not_active IP Right Cessation
- 2008-04-30 UA UAA200912129A patent/UA98328C2/uk unknown
-
2009
- 2009-10-28 IL IL201796A patent/IL201796A/en active IP Right Grant
-
2016
- 2016-02-29 CY CY20161100164T patent/CY1119269T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL2152261T3 (pl) | 2016-06-30 |
| HUE028713T2 (en) | 2016-12-28 |
| BRPI0810806A2 (pt) | 2014-10-29 |
| EP2152261B1 (en) | 2015-12-09 |
| KR20100017464A (ko) | 2010-02-16 |
| US9895334B2 (en) | 2018-02-20 |
| DK2152261T3 (en) | 2016-03-07 |
| IL201796A (en) | 2016-11-30 |
| EP2152261A1 (en) | 2010-02-17 |
| HRP20160181T1 (hr) | 2016-05-06 |
| WO2008131491A1 (en) | 2008-11-06 |
| UA98328C2 (uk) | 2012-05-10 |
| RU2506951C2 (ru) | 2014-02-20 |
| NZ580702A (en) | 2012-03-30 |
| SI2152261T1 (sl) | 2016-05-31 |
| IL201796A0 (en) | 2010-06-16 |
| EP2152261A4 (en) | 2013-01-02 |
| AU2008243705A1 (en) | 2008-11-06 |
| CA2685473C (en) | 2015-09-01 |
| CA2685473A1 (en) | 2008-11-06 |
| JP5497629B2 (ja) | 2014-05-21 |
| CY1119269T1 (el) | 2018-02-14 |
| JP2010524978A (ja) | 2010-07-22 |
| KR101485883B1 (ko) | 2015-01-27 |
| AU2008243705B2 (en) | 2013-10-10 |
| HK1134450A1 (zh) | 2010-04-30 |
| CN101742996A (zh) | 2010-06-16 |
| ES2564173T3 (es) | 2016-03-18 |
| CN101742996B (zh) | 2013-08-21 |
| MY154484A (en) | 2015-06-30 |
| RU2009144100A (ru) | 2011-06-10 |
| US20100204318A1 (en) | 2010-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or rights |
Owner name: LEO LABORATORIES LIMITED.* |
|
| FG | Grant or registration |