MX2009011366A - Metodos y composiciones para tratar y monitorear el tratamiento de trastornos asociados con il-13. - Google Patents
Metodos y composiciones para tratar y monitorear el tratamiento de trastornos asociados con il-13.Info
- Publication number
- MX2009011366A MX2009011366A MX2009011366A MX2009011366A MX2009011366A MX 2009011366 A MX2009011366 A MX 2009011366A MX 2009011366 A MX2009011366 A MX 2009011366A MX 2009011366 A MX2009011366 A MX 2009011366A MX 2009011366 A MX2009011366 A MX 2009011366A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- compositions
- treating
- associated disorders
- monitoring treatment
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000012544 monitoring process Methods 0.000 title 1
- 239000011230 binding agent Substances 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
Abstract
Se describen métodos y composiciones para reducir o inhibir, o prevenir o demorar el inicio de uno o más síntomas asociados con una fase temprana y/o tardía de un trastorno o una afección asociado con IL-13 usando agentes de unión a IL-13. También se describen métodos para evaluar la cinética y/o la eficacia de un agente de unión a IL-13 en el tratamiento o la prevención de un trastorno o una afección asociado con IL-13 en un sujeto, por ejemplo, un sujeto humano.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92593207P | 2007-04-23 | 2007-04-23 | |
| US92607807P | 2007-04-23 | 2007-04-23 | |
| PCT/US2008/061130 WO2008131376A2 (en) | 2007-04-23 | 2008-04-22 | Methods and compositions for treating and monitoring treatment of il-13-associated disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009011366A true MX2009011366A (es) | 2009-11-05 |
Family
ID=39689094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009011366A MX2009011366A (es) | 2007-04-23 | 2008-04-22 | Metodos y composiciones para tratar y monitorear el tratamiento de trastornos asociados con il-13. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20090068195A1 (es) |
| EP (1) | EP2137215A2 (es) |
| JP (1) | JP2010527916A (es) |
| CN (1) | CN101977935A (es) |
| AR (1) | AR066240A1 (es) |
| BR (1) | BRPI0810561A2 (es) |
| CA (1) | CA2685123A1 (es) |
| CL (1) | CL2008001182A1 (es) |
| MX (1) | MX2009011366A (es) |
| PA (1) | PA8778101A1 (es) |
| PE (1) | PE20090154A1 (es) |
| RU (1) | RU2009140134A (es) |
| TW (1) | TW200848429A (es) |
| WO (1) | WO2008131376A2 (es) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR049390A1 (es) | 2004-06-09 | 2006-07-26 | Wyeth Corp | Anticuerpos contra la interleuquina-13 humana y usos de los mismos |
| US7501121B2 (en) * | 2004-06-17 | 2009-03-10 | Wyeth | IL-13 binding agents |
| GB0509512D0 (en) * | 2005-05-10 | 2005-06-15 | Novartis Ag | Organic compounds |
| NZ588554A (en) * | 2008-04-29 | 2013-03-28 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| US20100260668A1 (en) * | 2008-04-29 | 2010-10-14 | Abbott Laboratories | Dual Variable Domain Immunoglobulins and Uses Thereof |
| CA2726087A1 (en) * | 2008-06-03 | 2009-12-10 | Tariq Ghayur | Dual variable domain immunoglobulins and uses thereof |
| CN102112494A (zh) * | 2008-06-03 | 2011-06-29 | 雅培制药有限公司 | 双重可变结构域免疫球蛋白及其用途 |
| CA2729949A1 (en) * | 2008-07-08 | 2010-01-14 | Abbott Laboratories | Prostaglandin e2 dual variable domain immunoglobulins and uses thereof |
| GB0905972D0 (en) | 2009-04-06 | 2009-05-20 | Medical Res Council | Antibodies against IL-17BR |
| TW201109438A (en) * | 2009-07-29 | 2011-03-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| UY32870A (es) * | 2009-09-01 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| EP2486940B1 (en) * | 2009-10-08 | 2017-10-04 | Aeon Medix Inc. | Composition comprising extracellular membrane vesicles derived from indoor air, and use thereof |
| CA2775959A1 (en) * | 2009-10-15 | 2011-04-21 | Abbott Laboratories | Dual variable domain immunoglobulins and uses thereof |
| UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| AU2011285852B2 (en) | 2010-08-03 | 2014-12-11 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
| PH12013500337A1 (en) | 2010-08-26 | 2017-08-23 | Abbvie Inc | Dual variable domain immunoglobulins and uses thereof |
| AU2011323521A1 (en) * | 2010-11-02 | 2013-06-20 | Abbott Laboratories | Dual variable domain immunoglobulins and uses thereof |
| ES2842895T3 (es) | 2010-12-06 | 2021-07-15 | Seagen Inc | Anticuerpos humanizados contra LIV-1 y uso de los mismos para tratar el cáncer |
| AU2011343570B2 (en) | 2010-12-16 | 2016-11-03 | Genentech, Inc. | Diagnosis and treatments relating to TH2 inhibition |
| SG193565A1 (en) * | 2011-03-31 | 2013-11-29 | Genentech Inc | Methods of administering beta7 integrin antagonists |
| AU2012283039A1 (en) | 2011-07-13 | 2014-01-30 | Abbvie Inc. | Methods and compositions for treating asthma using anti-IL-13 antibodies |
| CN104159920A (zh) | 2011-12-30 | 2014-11-19 | 艾伯维公司 | 针对il-13和/或il-17的双重可变结构域免疫球蛋白 |
| CA2864884A1 (en) * | 2012-03-27 | 2013-10-03 | Genentech, Inc. | Methods of prognosing, diagnosing and treating idiopathic pulmonary fibrosis |
| IN2014DN10408A (es) * | 2012-06-05 | 2015-08-14 | Univ Australian | |
| KR20180008921A (ko) | 2012-11-01 | 2018-01-24 | 애브비 인코포레이티드 | 항-vegf/dll4 이원 가변 도메인 면역글로불린 및 이의 용도 |
| EP2970459A2 (en) | 2013-03-15 | 2016-01-20 | AbbVie Inc. | Dual specific binding proteins directed against il-1beta and il-17 |
| WO2016094881A2 (en) | 2014-12-11 | 2016-06-16 | Abbvie Inc. | Lrp-8 binding proteins |
| TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
| HUE055139T2 (hu) * | 2015-08-07 | 2021-11-29 | Alx Oncology Inc | A SIRP-alfa domént vagy ennek variánsát tartalmazó készítmények |
| MA45324A (fr) | 2016-03-15 | 2019-01-23 | Seattle Genetics Inc | Polythérapie utilisant un adc-liv1 et un agent chimiothérapeutique |
| ES2981704T3 (es) | 2016-04-27 | 2024-10-10 | Abbvie Mfg Management Unlimited Company | Métodos de tratamiento de enfermedades en las que la actividad de IL-13 es perjudicial mediante la utilización de anticuerpos anti-IL-13 |
| CN109705217B (zh) * | 2017-10-25 | 2020-09-11 | 北京智仁美博生物科技有限公司 | 抗il-13抗体及其用途 |
| WO2020047326A2 (en) * | 2018-08-31 | 2020-03-05 | ALX Oncology Inc. | Decoy polypeptides |
| CA3134495A1 (en) * | 2019-03-26 | 2020-10-01 | Aslan Pharmaceuticals Pte Ltd | Treatment employing anti-il13r antibody or binding fragment thereof |
| AU2020282791A1 (en) | 2019-05-31 | 2021-12-09 | ALX Oncology Inc. | Methods of treating cancer with SIRP alpha Fc fusion in combination with an immune checkpoint inhibitor |
| CA3216908A1 (en) | 2021-05-13 | 2022-11-17 | ALX Oncology Inc. | Combination therapies for treating cancer |
| CN118255891B (zh) * | 2024-03-14 | 2025-03-11 | 北京赛斯维德生物科技有限公司 | 检测尿液11-脱氢血栓烷b2/肌酐的试剂盒及检测方法 |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225539A (en) * | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| AU600575B2 (en) * | 1987-03-18 | 1990-08-16 | Sb2, Inc. | Altered antibodies |
| US5359037A (en) * | 1988-09-12 | 1994-10-25 | Yeda Research And Development Co. Ltd. | Antibodies to TNF binding protein I |
| WO1990005183A1 (en) * | 1988-10-31 | 1990-05-17 | Immunex Corporation | Interleukin-4 receptors |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5011778A (en) * | 1989-05-23 | 1991-04-30 | Otsuka Pharmaceutical Co., Ltd. | Monoclonal antibodies directed to IL-1 activated endothelial cells and medicaments employing the monoclonal antibodies |
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| US5246701A (en) * | 1990-10-05 | 1993-09-21 | Ludwig Institute For Cancer Research | Method for inhibiting production of IgE by using IL-9 inhibitors |
| HU217099B (hu) * | 1991-03-29 | 1999-11-29 | Elf Sanofi Sa. | Eljárás citokin típusú aktivitással rendelkező fehérje, azt kódoló rekombináns DNS-szekvencia és a megfelelő transzformált sejtek és mikroorganizmusok előállítására |
| WO1992022653A1 (en) * | 1991-06-14 | 1992-12-23 | Genentech, Inc. | Method for making humanized antibodies |
| US5397703A (en) * | 1992-07-09 | 1995-03-14 | Cetus Oncology Corporation | Method for generation of antibodies to cell surface molecules |
| US5596072A (en) * | 1992-08-21 | 1997-01-21 | Schering Corporation | Method of refolding human IL-13 |
| IL110855A (en) * | 1993-09-02 | 1999-04-11 | Dartmouth College | Methods for inducing antigen-specific t cell tolerance |
| US5928904A (en) * | 1993-09-07 | 1999-07-27 | Smithkline Beecham Corporation | DNA encoding recombinant IL4 antibodies useful in treatment of IL4 mediated disorders |
| GB9415379D0 (en) * | 1994-07-29 | 1994-09-21 | Smithkline Beecham Plc | Novel compounds |
| US5696234A (en) * | 1994-08-01 | 1997-12-09 | Schering Corporation | Muteins of mammalian cytokine interleukin-13 |
| US5705154A (en) * | 1995-03-08 | 1998-01-06 | Schering Corporation | Humanized monoclonal antibodies against human interleukin-4 |
| US6911530B1 (en) * | 1995-10-23 | 2005-06-28 | Amrad Operations, Pty., Ltd. | Haemopoietin receptor and genetic sequences encoding same |
| FR2742156A1 (fr) * | 1995-12-06 | 1997-06-13 | Sanofi Sa | Polypeptide recepteur de l'il-13 |
| US6664227B1 (en) * | 1996-03-01 | 2003-12-16 | Genetics Institute, Llc | Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains |
| US7078494B1 (en) * | 1996-03-01 | 2006-07-18 | Genetics Institute, Llc | Antibodies to human IL-13bc and methods of their use in inhibiting IL-13 binding |
| US5710023A (en) * | 1996-03-01 | 1998-01-20 | Genetics Institute, Inc. | IL-13 cytokine receptor chain |
| GB9625899D0 (en) * | 1996-12-13 | 1997-01-29 | Glaxo Group Ltd | Substances and their uses |
| US6387615B2 (en) * | 1997-04-11 | 2002-05-14 | Isis Innovation Limited | Methods and materials for the diagnosis or prognosis of asthma |
| GB9723553D0 (en) * | 1997-11-07 | 1998-01-07 | Duff Gordon W | Prediction of the risk of chronic obstructive airway disease |
| CA2312208C (en) * | 1997-12-05 | 2011-01-25 | The Scripps Research Institute | Humanization of murine antibody |
| US6746839B1 (en) * | 1998-01-12 | 2004-06-08 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for an obstructive airway disease |
| US6576232B1 (en) * | 1998-04-03 | 2003-06-10 | The Penn State Research Foundation | IL13 mutants |
| US7083950B2 (en) * | 1998-09-25 | 2006-08-01 | Regeneron Pharmaceuticals, Inc. | High affinity fusion proteins and therapeutic and diagnostic methods for use |
| ES2277460T3 (es) * | 1998-12-14 | 2007-07-01 | Genetics Institute, Llc | Cadena del receptor de la citoquina. |
| US7553487B2 (en) * | 1998-12-14 | 2009-06-30 | Genetics Institute, Llc | Method and compositions for treating asthma |
| US6737056B1 (en) * | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| GB0004016D0 (en) * | 2000-02-22 | 2000-04-12 | Royal Brompton Hospital | Biological material and uses thereof |
| US6703360B2 (en) * | 2000-04-07 | 2004-03-09 | Heska Corporation | Compositions and methods related to canine IgG and canine IL-13 receptors |
| AU8867501A (en) * | 2000-09-01 | 2002-03-13 | Biogen Inc | Co-crystal structure of monoclonal antibody 5c8 and cd154, and use thereof in drug design |
| KR20100031769A (ko) * | 2000-12-28 | 2010-03-24 | 알투스 파마슈티컬스 인코포레이티드 | 전항체 및 이의 단편의 결정과 이의 제조 및 사용 방법 |
| GB0105360D0 (en) * | 2001-03-03 | 2001-04-18 | Glaxo Group Ltd | Chimaeric immunogens |
| AUPR544401A0 (en) * | 2001-06-04 | 2001-06-28 | Bischof, Robert Juergen | Animal model for allergy |
| MXPA03011158A (es) * | 2001-06-07 | 2004-02-27 | Wyeth Corp | Estructura de solucion de il - 13 y sus usos. |
| US7321026B2 (en) * | 2001-06-27 | 2008-01-22 | Skytech Technology Limited | Framework-patched immunoglobulins |
| US20040234499A1 (en) * | 2001-10-26 | 2004-11-25 | David Shealy | Asthma-related anti-IL-13 immunoglobulin derived proteins, compositions, methods and uses |
| US20040248260A1 (en) * | 2001-10-26 | 2004-12-09 | Heavner George A. | IL-13 mutein proteins, antibodies, compositions, methods and uses |
| US20050154192A1 (en) * | 2001-11-27 | 2005-07-14 | Kamon Shirakawa | Anti-il13 receptor alpha1 neutralizing antibody |
| CA2469082A1 (en) * | 2001-12-04 | 2003-06-12 | Raj K. Puri | Chimeric molecule for the treatment of th2-like cytokine mediated disorders |
| JP4432031B2 (ja) * | 2002-03-22 | 2010-03-17 | ズィナイス オペレーションズ ピーティーワイ.エルティーディー. | インターロイキン13受容体α1(IL−13Rα1)に対するモノクローナル抗体 |
| AU2003223497A1 (en) * | 2002-04-05 | 2003-10-27 | Centocor, Inc. | Asthma-related anti-il-13 immunoglobulin derived proteins, compositions, methods and uses |
| CA2480777A1 (en) * | 2002-05-01 | 2003-11-13 | Regeneron Pharmaceuticals, Inc. | Methods of using cytokine antagonists to treat hiv infection and aids |
| EP1552462B1 (en) * | 2002-06-14 | 2011-03-23 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Methods of treating and preventing colitis involving il-13 and nk-t cells |
| JP2004121218A (ja) * | 2002-08-06 | 2004-04-22 | Jenokkusu Soyaku Kenkyusho:Kk | 気管支喘息または慢性閉塞性肺疾患の検査方法 |
| GB0407315D0 (en) * | 2003-07-15 | 2004-05-05 | Cambridge Antibody Tech | Human antibody molecules |
| SI3718564T1 (sl) * | 2003-12-23 | 2024-01-31 | Genentech, Inc. | Nova protitelesa proti il 13 in uporaba le-teh |
| KR20060127415A (ko) * | 2003-12-24 | 2006-12-12 | 와이어쓰 | 천식의 치료방법 |
| US20050186146A1 (en) * | 2004-02-12 | 2005-08-25 | Nektar Therapeutics | Interleukin-13 antagonist powders, spray-dried particles, and methods |
| CA2557724A1 (en) * | 2004-02-27 | 2005-10-06 | Centocor, Inc. | Methods and compositions for treating il-13 related pathologies |
| US20090098142A1 (en) * | 2004-06-09 | 2009-04-16 | Kasaian Marion T | Methods and compositions for treating and monitoring treatment of IL-13-associated disorders |
| US20070048785A1 (en) * | 2004-06-09 | 2007-03-01 | Lin Laura L | Anti-IL-13 antibodies and complexes |
| AR049390A1 (es) * | 2004-06-09 | 2006-07-26 | Wyeth Corp | Anticuerpos contra la interleuquina-13 humana y usos de los mismos |
| US7501121B2 (en) * | 2004-06-17 | 2009-03-10 | Wyeth | IL-13 binding agents |
| EP2089057A2 (en) * | 2006-12-11 | 2009-08-19 | Wyeth | Methods and compositions for treating and monitoring treatment of il-13-associated disorders |
-
2008
- 2008-04-22 MX MX2009011366A patent/MX2009011366A/es not_active Application Discontinuation
- 2008-04-22 CN CN2008800213299A patent/CN101977935A/zh active Pending
- 2008-04-22 US US12/107,456 patent/US20090068195A1/en not_active Abandoned
- 2008-04-22 JP JP2010506427A patent/JP2010527916A/ja not_active Withdrawn
- 2008-04-22 AR ARP080101679A patent/AR066240A1/es unknown
- 2008-04-22 CA CA002685123A patent/CA2685123A1/en not_active Abandoned
- 2008-04-22 EP EP08746533A patent/EP2137215A2/en not_active Withdrawn
- 2008-04-22 WO PCT/US2008/061130 patent/WO2008131376A2/en not_active Ceased
- 2008-04-22 TW TW097114612A patent/TW200848429A/zh unknown
- 2008-04-22 BR BRPI0810561A patent/BRPI0810561A2/pt not_active IP Right Cessation
- 2008-04-22 RU RU2009140134/10A patent/RU2009140134A/ru not_active Application Discontinuation
- 2008-04-23 PE PE2008000699A patent/PE20090154A1/es not_active Application Discontinuation
- 2008-04-23 CL CL2008001182A patent/CL2008001182A1/es unknown
- 2008-04-23 PA PA20088778101A patent/PA8778101A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008131376A2 (en) | 2008-10-30 |
| CA2685123A1 (en) | 2008-10-30 |
| WO2008131376A3 (en) | 2009-02-05 |
| US20090068195A1 (en) | 2009-03-12 |
| RU2009140134A (ru) | 2011-05-27 |
| CL2008001182A1 (es) | 2009-01-16 |
| PA8778101A1 (es) | 2008-11-19 |
| CN101977935A (zh) | 2011-02-16 |
| EP2137215A2 (en) | 2009-12-30 |
| PE20090154A1 (es) | 2009-03-31 |
| AR066240A1 (es) | 2009-08-05 |
| JP2010527916A (ja) | 2010-08-19 |
| BRPI0810561A2 (pt) | 2019-09-24 |
| TW200848429A (en) | 2008-12-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2009011366A (es) | Metodos y composiciones para tratar y monitorear el tratamiento de trastornos asociados con il-13. | |
| WO2008122049A3 (en) | Methods and compositions for reduction of side effects of therapeutic treatments | |
| EP1742641A4 (en) | METHODS AND COMPOSITIONS FOR DETECTION AND TREATMENT OF RETINA DISEASES | |
| MXPA06014510A (es) | Composiciones y metodos para tratar trastornos inflamatorios. | |
| GB2463833A (en) | Methods and compositions for the treatment of neurological disorders | |
| ZA200700918B (en) | Compositions and methods for treating eye disorders and conditions | |
| WO2008137633A3 (en) | Methods of modulating cellular homeostatic pathways and cellular survival | |
| MX2010004450A (es) | Derivados heterociclo biciclicos y su uso como moduladores de la actividad de gpr119. | |
| SI2374472T1 (sl) | Sestavki in postopki za zdravljenje oftalmoloških motenj | |
| PL1761266T3 (pl) | Związki, preparaty i sposoby leczenia lub zapobiegania procesom zapalnym skóry | |
| MX2009005725A (es) | Metodos y composiciones para tratamiento y monitoreo de tratamiento de trastornos asociados con il-13. | |
| HK1213794A1 (zh) | 联合治疗及用於治疗脱髓鞘病症的用途 | |
| MX2010009724A (es) | Procedimientos de tratamiento del dolor inflamatorio-. | |
| WO2006052608A3 (en) | Treatment of obesity and related disorders | |
| IL186963A0 (en) | Methods and compositions for treating pain | |
| WO2010014595A3 (en) | Methods and compositions for delivering therapeutic agents in the treatment of b-cell related disorders | |
| IL202424A (en) | Telomerase activator compounds for use in the treatment of disorders and related conditions | |
| TN2010000214A1 (en) | Methods for treating obesity and obesity related diseases and disorders | |
| WO2009093213A3 (en) | Method for predicting and diagnosing brain tumor | |
| WO2008029169A3 (en) | Method of treating respiratory disorders | |
| WO2010075347A3 (en) | Treating hypertension with at least one angiotensin ii receptor blocker and chlorthalidone | |
| MX2009008135A (es) | Uso de histidinato de cromo para tratamiento de alteraciones cardiometabolicas. | |
| WO2009009417A3 (en) | Pharmaceutical compositions and methods of preventing, treating, or inhibiting inflammatory diseases, disorders, or conditions of the skin, and diseases, disorders, or conditions associated with collagen depletion | |
| EP1890712A4 (en) | COMPOSITIONS AND METHODS FOR TREATING PAIN | |
| IL200570A0 (en) | Combination therapy, composition and methods for the treatment of cardiovascular disorders |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |