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MX2009011179A - Variantes de enzimas asparaginasas y sus usos. - Google Patents

Variantes de enzimas asparaginasas y sus usos.

Info

Publication number
MX2009011179A
MX2009011179A MX2009011179A MX2009011179A MX2009011179A MX 2009011179 A MX2009011179 A MX 2009011179A MX 2009011179 A MX2009011179 A MX 2009011179A MX 2009011179 A MX2009011179 A MX 2009011179A MX 2009011179 A MX2009011179 A MX 2009011179A
Authority
MX
Mexico
Prior art keywords
asparaginase
enzyme variants
variants
asparaginase enzyme
relates
Prior art date
Application number
MX2009011179A
Other languages
English (en)
Inventor
Jan Metske Van Der Laan
Mark Cristiaan Stor
Ilse De Lange
Lisette Mohrmann
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of MX2009011179A publication Critical patent/MX2009011179A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/82Asparaginase (3.5.1.1)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20Removal of unwanted matter, e.g. deodorisation or detoxification
    • A23L5/25Removal of unwanted matter, e.g. deodorisation or detoxification using enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y305/00Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01001Asparaginase (3.5.1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se relaciona con variantes de polipéptidos de asparaginasa identificados recientemente de SEQ ID Nº 3, y con secuencias de polinucleótidos que codifican dichas nuevas variantes de asparaginasas. Además, la invención se relaciona con el uso de estas nuevas variantes de asparaginasa en procesos industriales.
MX2009011179A 2007-04-20 2008-04-17 Variantes de enzimas asparaginasas y sus usos. MX2009011179A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP07106620 2007-04-20
EP07106660 2007-04-20
EP07106612 2007-04-20
EP07106662 2007-04-20
EP07106664 2007-04-20
PCT/EP2008/054692 WO2008128974A1 (en) 2007-04-20 2008-04-17 Asparaginase enzyme variants and uses thereof

Publications (1)

Publication Number Publication Date
MX2009011179A true MX2009011179A (es) 2010-01-20

Family

ID=39711125

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011179A MX2009011179A (es) 2007-04-20 2008-04-17 Variantes de enzimas asparaginasas y sus usos.

Country Status (14)

Country Link
US (2) US8617868B2 (es)
EP (3) EP2139997B1 (es)
JP (1) JP2010524447A (es)
CN (1) CN103397012A (es)
AR (1) AR069362A1 (es)
AU (1) AU2008240796A1 (es)
BR (1) BRPI0810480B1 (es)
CA (1) CA2683078C (es)
DK (1) DK2139997T3 (es)
EA (1) EA018424B1 (es)
ES (1) ES2524343T3 (es)
IL (1) IL201019A0 (es)
MX (1) MX2009011179A (es)
WO (1) WO2008128974A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010524447A (ja) 2007-04-20 2010-07-22 ディーエスエム アイピー アセッツ ビー.ブイ. アスパラギナーゼ酵素変異体およびその使用
EP2378897B1 (en) * 2008-12-16 2017-07-19 Novozymes A/S Stabilization of asparaginase
US20110129569A1 (en) 2009-11-26 2011-06-02 Dsm Ip Assets B.V. Method to produce fried vegetable products
US20120100249A1 (en) * 2010-04-27 2012-04-26 Dsm Ip Assets B.V. Novel asparaginase enzyme
CA2802126A1 (en) * 2010-07-14 2012-01-19 Nestec S.A. Asparaginase from basidiomycetes
CA2817224A1 (en) 2010-11-19 2012-05-24 Novozymes North America, Inc. Processes of producing a fermentation product
MX2015001969A (es) 2012-08-17 2015-05-15 Novozymes As Variantes de asparaginasa termoestables y polinucleotidos que las codifican.
US9427008B2 (en) 2012-09-06 2016-08-30 Mycotechnology, Inc. Method of myceliation of agricultural substates for producing functional foods and nutraceuticals
US9068171B2 (en) 2012-09-06 2015-06-30 Mycotechnology, Inc. Method for myceliating coffee
CN105102612B (zh) 2012-12-06 2020-11-17 恩立夫克治疗有限责任公司 治疗性凋亡细胞制剂、其制备方法以及其用途
WO2015033344A1 (en) 2013-09-05 2015-03-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods and kits for inhibiting pathogenicity of group a streptococcus (gas) or group g streptococcus (ggs)
US10231469B2 (en) 2014-03-15 2019-03-19 Mycotechnology, Inc. Myceliated products and methods for making myceliated products from cacao and other agricultural substrates
RU2545722C1 (ru) * 2014-03-27 2015-04-10 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") МУТАНТНАЯ РЕКОМБИНАНТНАЯ L-АСПАРАГИНАЗА Wolinella succinogenes (ВАРИАНТЫ)
US10709157B2 (en) 2014-08-26 2020-07-14 Mycotechnology, Inc. Methods for the production and use of mycelial liquid tissue culture
US9572364B2 (en) 2014-08-26 2017-02-21 Mycotechnology, Inc. Methods for the production and use of mycelial liquid tissue culture
EP3185700B1 (en) 2014-08-26 2021-07-28 Mycotechnology, Inc. Methods for the production and use of mycelial liquid tissue culture
US10980257B2 (en) 2015-02-26 2021-04-20 Myco Technology, Inc. Methods for lowering gluten content using fungal cultures
US10806101B2 (en) 2016-04-14 2020-10-20 Mycotechnology, Inc. Methods for the production and use of myceliated high protein food compositions
CA3018423C (en) 2016-04-14 2021-02-23 Mycotechnology, Inc. Methods for the production and use of myceliated high protein food compositions
US11166477B2 (en) 2016-04-14 2021-11-09 Mycotechnology, Inc. Myceliated vegetable protein and food compositions comprising same
JP7109427B2 (ja) 2016-06-01 2022-07-29 セルヴィエ アイピー ユーケー リミテッド ポリアルキレンオキシド-アスパラギナーゼの製剤ならびにその製造法および使用法
US20210299233A1 (en) 2018-07-12 2021-09-30 The Children's Medical Center Corporation Method for treating cancer
US12274283B2 (en) 2018-09-20 2025-04-15 The Better Meat Co. Enhanced aerobic fermentation methods for producing edible fungal mycelium blended meats and meat analogue compositions
EP3852543A1 (en) 2018-09-20 2021-07-28 The Better Meat Company Enhanced aerobic fermentation methods for producing edible fungal mycelium blended meats and meat analogue compositions
CN109266635B (zh) * 2018-11-20 2020-12-01 江南大学 一种酶活提高的l-天冬酰胺酶突变体及其构建方法
EP4525615A2 (en) 2022-05-14 2025-03-26 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3819540B2 (ja) * 1996-06-07 2006-09-13 株式会社林原生物化学研究所 L−アスパラギナーゼ活性を有する哺乳類由来のポリペプチド
EP1523679A4 (en) 2002-04-01 2007-06-20 Novozymes Inc METHODS FOR PRODUCING SECRETED POLYPEPTIDES WITH L-ASPARAGINASE ACTIVITY
WO2004074468A1 (en) 2002-05-30 2004-09-02 Dsm Ip Assets B.V. Novel pectinases and uses thereof
US7524519B2 (en) 2002-09-20 2009-04-28 The Procter & Gamble Company Method for reducing acrylamide in foods, foods having reduced levels of acrylamide, and article of commerce
US7555108B2 (en) 2002-10-01 2009-06-30 Nortel Networks Limited Presence information for telephony users
ATE372059T1 (de) 2002-10-11 2007-09-15 Novozymes As Verfahren zur herstellung von wärmebehandelten produkten
US20040101607A1 (en) 2002-11-22 2004-05-27 The Procter & Gamble Company Method for reducing acrylamide in foods, foods having reduced levels of acrylamide, and article of commerce
PL395660A1 (pl) 2002-12-19 2011-09-12 Dsm Ip Assets B. V. Izolowane polinukleotydy, wektor, sposób wytwarzania polinukleotydu, izolowane asparaginazy, rekombinowana asparaginaza, sposób wytwarzania asparaginazy oraz rekombinowane komórki gospodarza
WO2006128843A1 (en) * 2005-05-31 2006-12-07 Dsm Ip Assets B.V. Novel process for enzymatic acrylamide reduction in food products
ES2519466T3 (es) * 2007-03-09 2014-11-07 Novozymes A/S Asparaginasas termoestables
US20080228595A1 (en) 2007-03-13 2008-09-18 Swapedo.Com, Inc. System for supporting electronic commerce in social networks
WO2008128975A1 (en) 2007-04-20 2008-10-30 Dsm Ip Assets B.V. Novel asparaginases and uses thereof
JP2010524447A (ja) 2007-04-20 2010-07-22 ディーエスエム アイピー アセッツ ビー.ブイ. アスパラギナーゼ酵素変異体およびその使用
US20120100249A1 (en) 2010-04-27 2012-04-26 Dsm Ip Assets B.V. Novel asparaginase enzyme

Also Published As

Publication number Publication date
WO2008128974A1 (en) 2008-10-30
JP2010524447A (ja) 2010-07-22
US20100183765A1 (en) 2010-07-22
BRPI0810480B1 (pt) 2022-05-17
CA2683078A1 (en) 2008-10-30
IL201019A0 (en) 2011-08-01
CN103397012A (zh) 2013-11-20
CA2683078C (en) 2016-03-29
US8617868B2 (en) 2013-12-31
US20140099401A1 (en) 2014-04-10
EP2662444A1 (en) 2013-11-13
AR069362A1 (es) 2010-01-20
AU2008240796A1 (en) 2008-10-30
EA018424B1 (ru) 2013-07-30
EA200901430A1 (ru) 2010-04-30
EP2139997B1 (en) 2014-09-24
DK2139997T3 (en) 2014-12-08
BRPI0810480A2 (pt) 2014-10-07
EP2139997A1 (en) 2010-01-06
EP2662443A1 (en) 2013-11-13
US9127266B2 (en) 2015-09-08
ES2524343T3 (es) 2014-12-05

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