MX2009011179A - Variantes de enzimas asparaginasas y sus usos. - Google Patents
Variantes de enzimas asparaginasas y sus usos.Info
- Publication number
- MX2009011179A MX2009011179A MX2009011179A MX2009011179A MX2009011179A MX 2009011179 A MX2009011179 A MX 2009011179A MX 2009011179 A MX2009011179 A MX 2009011179A MX 2009011179 A MX2009011179 A MX 2009011179A MX 2009011179 A MX2009011179 A MX 2009011179A
- Authority
- MX
- Mexico
- Prior art keywords
- asparaginase
- enzyme variants
- variants
- asparaginase enzyme
- relates
- Prior art date
Links
- 102000015790 Asparaginase Human genes 0.000 title abstract 4
- 108010024976 Asparaginase Proteins 0.000 title abstract 4
- 229960003272 asparaginase Drugs 0.000 abstract 3
- DCXYFEDJOCDNAF-UHFFFAOYSA-M asparaginate Chemical compound [O-]C(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-M 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
- C12N9/82—Asparaginase (3.5.1.1)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/06—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
- A23L5/25—Removal of unwanted matter, e.g. deodorisation or detoxification using enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
- C12Y305/01001—Asparaginase (3.5.1.1)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- General Preparation And Processing Of Foods (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se relaciona con variantes de polipéptidos de asparaginasa identificados recientemente de SEQ ID Nº 3, y con secuencias de polinucleótidos que codifican dichas nuevas variantes de asparaginasas. Además, la invención se relaciona con el uso de estas nuevas variantes de asparaginasa en procesos industriales.
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07106620 | 2007-04-20 | ||
| EP07106660 | 2007-04-20 | ||
| EP07106612 | 2007-04-20 | ||
| EP07106662 | 2007-04-20 | ||
| EP07106664 | 2007-04-20 | ||
| PCT/EP2008/054692 WO2008128974A1 (en) | 2007-04-20 | 2008-04-17 | Asparaginase enzyme variants and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009011179A true MX2009011179A (es) | 2010-01-20 |
Family
ID=39711125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009011179A MX2009011179A (es) | 2007-04-20 | 2008-04-17 | Variantes de enzimas asparaginasas y sus usos. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8617868B2 (es) |
| EP (3) | EP2139997B1 (es) |
| JP (1) | JP2010524447A (es) |
| CN (1) | CN103397012A (es) |
| AR (1) | AR069362A1 (es) |
| AU (1) | AU2008240796A1 (es) |
| BR (1) | BRPI0810480B1 (es) |
| CA (1) | CA2683078C (es) |
| DK (1) | DK2139997T3 (es) |
| EA (1) | EA018424B1 (es) |
| ES (1) | ES2524343T3 (es) |
| IL (1) | IL201019A0 (es) |
| MX (1) | MX2009011179A (es) |
| WO (1) | WO2008128974A1 (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010524447A (ja) | 2007-04-20 | 2010-07-22 | ディーエスエム アイピー アセッツ ビー.ブイ. | アスパラギナーゼ酵素変異体およびその使用 |
| EP2378897B1 (en) * | 2008-12-16 | 2017-07-19 | Novozymes A/S | Stabilization of asparaginase |
| US20110129569A1 (en) | 2009-11-26 | 2011-06-02 | Dsm Ip Assets B.V. | Method to produce fried vegetable products |
| US20120100249A1 (en) * | 2010-04-27 | 2012-04-26 | Dsm Ip Assets B.V. | Novel asparaginase enzyme |
| CA2802126A1 (en) * | 2010-07-14 | 2012-01-19 | Nestec S.A. | Asparaginase from basidiomycetes |
| CA2817224A1 (en) | 2010-11-19 | 2012-05-24 | Novozymes North America, Inc. | Processes of producing a fermentation product |
| MX2015001969A (es) | 2012-08-17 | 2015-05-15 | Novozymes As | Variantes de asparaginasa termoestables y polinucleotidos que las codifican. |
| US9427008B2 (en) | 2012-09-06 | 2016-08-30 | Mycotechnology, Inc. | Method of myceliation of agricultural substates for producing functional foods and nutraceuticals |
| US9068171B2 (en) | 2012-09-06 | 2015-06-30 | Mycotechnology, Inc. | Method for myceliating coffee |
| CN105102612B (zh) | 2012-12-06 | 2020-11-17 | 恩立夫克治疗有限责任公司 | 治疗性凋亡细胞制剂、其制备方法以及其用途 |
| WO2015033344A1 (en) | 2013-09-05 | 2015-03-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Methods and kits for inhibiting pathogenicity of group a streptococcus (gas) or group g streptococcus (ggs) |
| US10231469B2 (en) | 2014-03-15 | 2019-03-19 | Mycotechnology, Inc. | Myceliated products and methods for making myceliated products from cacao and other agricultural substrates |
| RU2545722C1 (ru) * | 2014-03-27 | 2015-04-10 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") | МУТАНТНАЯ РЕКОМБИНАНТНАЯ L-АСПАРАГИНАЗА Wolinella succinogenes (ВАРИАНТЫ) |
| US10709157B2 (en) | 2014-08-26 | 2020-07-14 | Mycotechnology, Inc. | Methods for the production and use of mycelial liquid tissue culture |
| US9572364B2 (en) | 2014-08-26 | 2017-02-21 | Mycotechnology, Inc. | Methods for the production and use of mycelial liquid tissue culture |
| EP3185700B1 (en) | 2014-08-26 | 2021-07-28 | Mycotechnology, Inc. | Methods for the production and use of mycelial liquid tissue culture |
| US10980257B2 (en) | 2015-02-26 | 2021-04-20 | Myco Technology, Inc. | Methods for lowering gluten content using fungal cultures |
| US10806101B2 (en) | 2016-04-14 | 2020-10-20 | Mycotechnology, Inc. | Methods for the production and use of myceliated high protein food compositions |
| CA3018423C (en) | 2016-04-14 | 2021-02-23 | Mycotechnology, Inc. | Methods for the production and use of myceliated high protein food compositions |
| US11166477B2 (en) | 2016-04-14 | 2021-11-09 | Mycotechnology, Inc. | Myceliated vegetable protein and food compositions comprising same |
| JP7109427B2 (ja) | 2016-06-01 | 2022-07-29 | セルヴィエ アイピー ユーケー リミテッド | ポリアルキレンオキシド-アスパラギナーゼの製剤ならびにその製造法および使用法 |
| US20210299233A1 (en) | 2018-07-12 | 2021-09-30 | The Children's Medical Center Corporation | Method for treating cancer |
| US12274283B2 (en) | 2018-09-20 | 2025-04-15 | The Better Meat Co. | Enhanced aerobic fermentation methods for producing edible fungal mycelium blended meats and meat analogue compositions |
| EP3852543A1 (en) | 2018-09-20 | 2021-07-28 | The Better Meat Company | Enhanced aerobic fermentation methods for producing edible fungal mycelium blended meats and meat analogue compositions |
| CN109266635B (zh) * | 2018-11-20 | 2020-12-01 | 江南大学 | 一种酶活提高的l-天冬酰胺酶突变体及其构建方法 |
| EP4525615A2 (en) | 2022-05-14 | 2025-03-26 | Novozymes A/S | Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3819540B2 (ja) * | 1996-06-07 | 2006-09-13 | 株式会社林原生物化学研究所 | L−アスパラギナーゼ活性を有する哺乳類由来のポリペプチド |
| EP1523679A4 (en) | 2002-04-01 | 2007-06-20 | Novozymes Inc | METHODS FOR PRODUCING SECRETED POLYPEPTIDES WITH L-ASPARAGINASE ACTIVITY |
| WO2004074468A1 (en) | 2002-05-30 | 2004-09-02 | Dsm Ip Assets B.V. | Novel pectinases and uses thereof |
| US7524519B2 (en) | 2002-09-20 | 2009-04-28 | The Procter & Gamble Company | Method for reducing acrylamide in foods, foods having reduced levels of acrylamide, and article of commerce |
| US7555108B2 (en) | 2002-10-01 | 2009-06-30 | Nortel Networks Limited | Presence information for telephony users |
| ATE372059T1 (de) | 2002-10-11 | 2007-09-15 | Novozymes As | Verfahren zur herstellung von wärmebehandelten produkten |
| US20040101607A1 (en) | 2002-11-22 | 2004-05-27 | The Procter & Gamble Company | Method for reducing acrylamide in foods, foods having reduced levels of acrylamide, and article of commerce |
| PL395660A1 (pl) | 2002-12-19 | 2011-09-12 | Dsm Ip Assets B. V. | Izolowane polinukleotydy, wektor, sposób wytwarzania polinukleotydu, izolowane asparaginazy, rekombinowana asparaginaza, sposób wytwarzania asparaginazy oraz rekombinowane komórki gospodarza |
| WO2006128843A1 (en) * | 2005-05-31 | 2006-12-07 | Dsm Ip Assets B.V. | Novel process for enzymatic acrylamide reduction in food products |
| ES2519466T3 (es) * | 2007-03-09 | 2014-11-07 | Novozymes A/S | Asparaginasas termoestables |
| US20080228595A1 (en) | 2007-03-13 | 2008-09-18 | Swapedo.Com, Inc. | System for supporting electronic commerce in social networks |
| WO2008128975A1 (en) | 2007-04-20 | 2008-10-30 | Dsm Ip Assets B.V. | Novel asparaginases and uses thereof |
| JP2010524447A (ja) | 2007-04-20 | 2010-07-22 | ディーエスエム アイピー アセッツ ビー.ブイ. | アスパラギナーゼ酵素変異体およびその使用 |
| US20120100249A1 (en) | 2010-04-27 | 2012-04-26 | Dsm Ip Assets B.V. | Novel asparaginase enzyme |
-
2008
- 2008-04-17 JP JP2010503508A patent/JP2010524447A/ja active Pending
- 2008-04-17 WO PCT/EP2008/054692 patent/WO2008128974A1/en not_active Ceased
- 2008-04-17 BR BRPI0810480-8A patent/BRPI0810480B1/pt active IP Right Grant
- 2008-04-17 EA EA200901430A patent/EA018424B1/ru not_active IP Right Cessation
- 2008-04-17 ES ES08749598.2T patent/ES2524343T3/es active Active
- 2008-04-17 MX MX2009011179A patent/MX2009011179A/es unknown
- 2008-04-17 CN CN2013102693448A patent/CN103397012A/zh active Pending
- 2008-04-17 CA CA2683078A patent/CA2683078C/en not_active Expired - Fee Related
- 2008-04-17 EP EP08749598.2A patent/EP2139997B1/en active Active
- 2008-04-17 DK DK08749598.2T patent/DK2139997T3/en active
- 2008-04-17 US US12/596,710 patent/US8617868B2/en active Active
- 2008-04-17 AU AU2008240796A patent/AU2008240796A1/en not_active Abandoned
- 2008-04-17 EP EP20130175921 patent/EP2662443A1/en not_active Withdrawn
- 2008-04-17 EP EP20130175926 patent/EP2662444A1/en not_active Withdrawn
- 2008-04-18 AR ARP080101641 patent/AR069362A1/es unknown
-
2009
- 2009-09-17 IL IL201019A patent/IL201019A0/en unknown
-
2013
- 2013-11-08 US US14/075,711 patent/US9127266B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008128974A1 (en) | 2008-10-30 |
| JP2010524447A (ja) | 2010-07-22 |
| US20100183765A1 (en) | 2010-07-22 |
| BRPI0810480B1 (pt) | 2022-05-17 |
| CA2683078A1 (en) | 2008-10-30 |
| IL201019A0 (en) | 2011-08-01 |
| CN103397012A (zh) | 2013-11-20 |
| CA2683078C (en) | 2016-03-29 |
| US8617868B2 (en) | 2013-12-31 |
| US20140099401A1 (en) | 2014-04-10 |
| EP2662444A1 (en) | 2013-11-13 |
| AR069362A1 (es) | 2010-01-20 |
| AU2008240796A1 (en) | 2008-10-30 |
| EA018424B1 (ru) | 2013-07-30 |
| EA200901430A1 (ru) | 2010-04-30 |
| EP2139997B1 (en) | 2014-09-24 |
| DK2139997T3 (en) | 2014-12-08 |
| BRPI0810480A2 (pt) | 2014-10-07 |
| EP2139997A1 (en) | 2010-01-06 |
| EP2662443A1 (en) | 2013-11-13 |
| US9127266B2 (en) | 2015-09-08 |
| ES2524343T3 (es) | 2014-12-05 |
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