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MX2009006751A - Sphingosine-1 -phosphate receptor agonist and antagonist compounds. - Google Patents

Sphingosine-1 -phosphate receptor agonist and antagonist compounds.

Info

Publication number
MX2009006751A
MX2009006751A MX2009006751A MX2009006751A MX2009006751A MX 2009006751 A MX2009006751 A MX 2009006751A MX 2009006751 A MX2009006751 A MX 2009006751A MX 2009006751 A MX2009006751 A MX 2009006751A MX 2009006751 A MX2009006751 A MX 2009006751A
Authority
MX
Mexico
Prior art keywords
sphingosine
receptor agonist
antagonist compounds
phosphate receptor
receptor family
Prior art date
Application number
MX2009006751A
Other languages
Spanish (es)
Inventor
Shannon R Fix-Stenzel
Thomas D Gordon
Grier A Wallace
Pintipa Grongsaard
Kevin P Cusack
Adrian D Hobson
Eric C Breinlinger
Graham K Ansell
Martin E Hayes
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39562856&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009006751(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX2009006751A publication Critical patent/MX2009006751A/en

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    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D231/08—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen or sulfur atoms directly attached to ring carbon atoms
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    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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Abstract

The present invention is directed to novel, potent, and selective agents, which are agonists or antagonists of the one or more of the individual receptors of the S1P receptor family. The compounds of the invention are useful as therapeutics for treating medical conditions associated with agonism or antagonism of the individual receptors of the S1P receptor family.
MX2009006751A 2006-12-21 2007-12-21 Sphingosine-1 -phosphate receptor agonist and antagonist compounds. MX2009006751A (en)

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PCT/US2007/026263 WO2008079382A1 (en) 2006-12-21 2007-12-21 Sphingosine-1 -phosphate receptor agonist and antagonist compounds

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