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MX2009005966A - Derivados de isoquinolona sustituidos con cicloalquilamina. - Google Patents

Derivados de isoquinolona sustituidos con cicloalquilamina.

Info

Publication number
MX2009005966A
MX2009005966A MX2009005966A MX2009005966A MX2009005966A MX 2009005966 A MX2009005966 A MX 2009005966A MX 2009005966 A MX2009005966 A MX 2009005966A MX 2009005966 A MX2009005966 A MX 2009005966A MX 2009005966 A MX2009005966 A MX 2009005966A
Authority
MX
Mexico
Prior art keywords
isoquinolone derivatives
substituted isoquinolone
rho
cycloalkylamine
cycloalkylamine substituted
Prior art date
Application number
MX2009005966A
Other languages
English (en)
Inventor
Joachim Brendel
Armin Hofmeister
Oliver Plettenburg
Matthias Loehn
John Weston
Katrin Lorenz
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38565513&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009005966(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of MX2009005966A publication Critical patent/MX2009005966A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Oncology (AREA)

Abstract

La invención se refiere a derivados de isoquinolona sustituidos en la posición 6, de fórmula (I) (ver fórmula I) útiles para el tratamiento y/o prevención de enfermedades asociadas con la Rho-quinasa y/o la fosforilación mediada por la Rho-quinasa de la fosfatasa de la cadena ligera de miosina, y a composiciones que contienen tales compuestos.
MX2009005966A 2006-12-27 2007-12-19 Derivados de isoquinolona sustituidos con cicloalquilamina. MX2009005966A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06026899 2006-12-27
PCT/EP2007/011164 WO2008077551A1 (en) 2006-12-27 2007-12-19 Cycloalkylamine substituted isoquinolone derivatives

Publications (1)

Publication Number Publication Date
MX2009005966A true MX2009005966A (es) 2009-06-15

Family

ID=38565513

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005966A MX2009005966A (es) 2006-12-27 2007-12-19 Derivados de isoquinolona sustituidos con cicloalquilamina.

Country Status (30)

Country Link
US (1) US8742116B2 (es)
EP (1) EP2125745B1 (es)
JP (1) JP5405314B2 (es)
KR (1) KR101474228B1 (es)
CN (1) CN101595094B (es)
AR (1) AR064492A1 (es)
AU (1) AU2007338407B2 (es)
BR (1) BRPI0722064A2 (es)
CA (1) CA2673917C (es)
CL (1) CL2007003821A1 (es)
CO (1) CO6210726A2 (es)
CR (1) CR10813A (es)
DO (1) DOP2009000164A (es)
EC (1) ECSP099467A (es)
ES (1) ES2625266T3 (es)
GT (1) GT200900179A (es)
IL (1) IL199540A (es)
MA (1) MA31075B1 (es)
MX (1) MX2009005966A (es)
MY (1) MY155009A (es)
NI (1) NI200900108A (es)
NO (1) NO20092422L (es)
NZ (1) NZ577980A (es)
RU (1) RU2457203C2 (es)
SV (1) SV2009003318A (es)
TN (1) TN2009000269A1 (es)
TW (1) TWI434689B (es)
UY (1) UY30843A1 (es)
WO (1) WO2008077551A1 (es)
ZA (1) ZA200903551B (es)

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