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MX2009005813A - Procedimiento para la preparacion de betamimeticos. - Google Patents

Procedimiento para la preparacion de betamimeticos.

Info

Publication number
MX2009005813A
MX2009005813A MX2009005813A MX2009005813A MX2009005813A MX 2009005813 A MX2009005813 A MX 2009005813A MX 2009005813 A MX2009005813 A MX 2009005813A MX 2009005813 A MX2009005813 A MX 2009005813A MX 2009005813 A MX2009005813 A MX 2009005813A
Authority
MX
Mexico
Prior art keywords
alkyl
sup
betamimetics
producing
halogen
Prior art date
Application number
MX2009005813A
Other languages
English (en)
Inventor
Juan M Rodriguez Dehli
Robert Hagenkoetter
Michael Schul
Christian Stange
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MX2009005813A publication Critical patent/MX2009005813A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a un procedimiento para la preparación de betamiméticos de Fórmula 1, (ver fórmula 1) en la cual n significa 1 o 2; R1 significa hidrógeno, halógeno, alquilo-C1-4 u O-alquilo-C1-4; R2 significa hidrógeno, halógeno, alquilo-C1-4 u O-alquilo-C1-4; R3 significa hidrógeno, alquilo-C1-4, OH, halógeno, O-alquilo-C1-4, O-alquilen-C1-4-COOH, O-alquilen-C1-4-COO-alquilo-C1-4.
MX2009005813A 2007-01-25 2008-01-24 Procedimiento para la preparacion de betamimeticos. MX2009005813A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07101130 2007-01-25
PCT/EP2008/050800 WO2008090193A2 (de) 2007-01-25 2008-01-24 Verfahren zur herstellung von betamimetika

Publications (1)

Publication Number Publication Date
MX2009005813A true MX2009005813A (es) 2009-06-16

Family

ID=39271623

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005813A MX2009005813A (es) 2007-01-25 2008-01-24 Procedimiento para la preparacion de betamimeticos.

Country Status (21)

Country Link
US (1) US20100022770A1 (es)
EP (1) EP2125759B1 (es)
JP (1) JP5409387B2 (es)
KR (1) KR101456872B1 (es)
CN (1) CN101578274B (es)
AR (1) AR065017A1 (es)
AT (1) ATE518847T1 (es)
AU (1) AU2008208813B2 (es)
BR (1) BRPI0807806A2 (es)
CA (1) CA2675094A1 (es)
CL (1) CL2008000222A1 (es)
DK (1) DK2125759T3 (es)
ES (1) ES2370952T3 (es)
IL (1) IL199985A (es)
MX (1) MX2009005813A (es)
NZ (1) NZ579007A (es)
PL (1) PL2125759T3 (es)
RU (1) RU2462460C2 (es)
TW (1) TWI409071B (es)
WO (1) WO2008090193A2 (es)
ZA (1) ZA200903599B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7056916B2 (en) * 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
CN101208316B (zh) 2005-08-15 2012-05-09 贝林格尔·英格海姆国际有限公司 制备β-模拟物的方法
US8888429B2 (en) 2009-12-22 2014-11-18 Jpmorgan Chase Bank, N.A. Nut with lug flare
WO2014056840A1 (en) 2012-10-09 2014-04-17 Boehringer Ingelheim International Gmbh Beta-2-adrenoceptor agonist for the treatment of cough
WO2016038628A2 (en) 2014-09-09 2016-03-17 Reddy G Pratap A process for preparing olodaterol and intermediates thereof
JP2019536812A (ja) 2016-12-12 2019-12-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング オロダテロールとの同時投与による間質性肺疾患の処置方法に使用するためのニンテダニブ
DK3558954T3 (da) 2016-12-20 2021-12-06 Inke Sa Forbedret proces til fremstilling af r-6-hydroxy-8-[1-hydroxy-2-[2-(4methoxyphenyl)-1,1-dimethylethylaminoethyl]-2h-1,4-benzoxazin-3(4h)-one hydrochloride
US20190117021A1 (en) * 2017-10-25 2019-04-25 Scott Amron Mixing device for stirring the contents of disposable drinking cups
CN111630033A (zh) 2018-01-23 2020-09-04 巴斯夫欧洲公司 任选取代的二氢异喹啉的制备
WO2019145174A1 (en) 2018-01-23 2019-08-01 Basf Se Preparation of optionally substituted 5-substituted pyridine
EP3743416B1 (en) 2018-01-23 2023-03-15 Basf Se Halogenation of pyridine derivatives
US11613549B2 (en) 2018-01-23 2023-03-28 Basf Se Bromination of pyridine derivatives
CN109096218B (zh) * 2018-08-06 2020-10-27 上海方予健康医药科技有限公司 盐酸奥达特罗晶型a及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS596860B2 (ja) * 1975-05-19 1984-02-15 オオツカセイヤク カブシキガイシヤ ５−〔（２−アルキルアミノ−１−ヒドロキシ）アルキル〕カルボスチリル誘導体の製造法
DE3134590A1 (de) * 1981-09-01 1983-03-10 Boehringer Ingelheim KG, 6507 Ingelheim Neue benzo-heterocyclen
AU2003239880A1 (en) * 2002-05-28 2003-12-12 Theravance, Inc. ALKOXY ARYL Beta2 ADRENERGIC RECEPTOR AGONISTS
DE10253282A1 (de) * 2002-11-15 2004-05-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
WO2005110990A1 (de) * 2004-05-13 2005-11-24 Boehringer Ingelheim International Gmbh Hydroxy-substituierte benzkondensierte heterozyklen als betaagonisten zur behandlung von atemwegserkrankungen
DE102004024454A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US7220742B2 (en) * 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
JP2006036760A (ja) * 2004-06-24 2006-02-09 Sankyo Co Ltd Ｎ−カルボニル飽和複素環類の製造方法及びその合成中間体
CN101208316B (zh) * 2005-08-15 2012-05-09 贝林格尔·英格海姆国际有限公司 制备β-模拟物的方法

Also Published As

Publication number Publication date
AU2008208813B2 (en) 2013-05-09
ATE518847T1 (de) 2011-08-15
KR20090101507A (ko) 2009-09-28
ZA200903599B (en) 2010-07-28
TWI409071B (zh) 2013-09-21
DK2125759T3 (da) 2011-09-19
AR065017A1 (es) 2009-05-13
KR101456872B1 (ko) 2014-10-31
RU2462460C2 (ru) 2012-09-27
CL2008000222A1 (es) 2008-05-23
WO2008090193A2 (de) 2008-07-31
TW200840586A (en) 2008-10-16
PL2125759T3 (pl) 2011-12-30
IL199985A (en) 2013-07-31
JP2010516739A (ja) 2010-05-20
EP2125759A2 (de) 2009-12-02
JP5409387B2 (ja) 2014-02-05
RU2009131835A (ru) 2011-02-27
WO2008090193A3 (de) 2008-10-09
AU2008208813A1 (en) 2008-07-31
ES2370952T3 (es) 2011-12-26
EP2125759B1 (de) 2011-08-03
CA2675094A1 (en) 2008-07-31
CN101578274B (zh) 2012-08-29
US20100022770A1 (en) 2010-01-28
NZ579007A (en) 2012-02-24
BRPI0807806A2 (pt) 2014-06-17
CN101578274A (zh) 2009-11-11
IL199985A0 (en) 2010-04-15

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