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MX2009005619A - Formas poliformicas del deferasirox (icl670a). - Google Patents

Formas poliformicas del deferasirox (icl670a).

Info

Publication number
MX2009005619A
MX2009005619A MX2009005619A MX2009005619A MX2009005619A MX 2009005619 A MX2009005619 A MX 2009005619A MX 2009005619 A MX2009005619 A MX 2009005619A MX 2009005619 A MX2009005619 A MX 2009005619A MX 2009005619 A MX2009005619 A MX 2009005619A
Authority
MX
Mexico
Prior art keywords
icl670a
deferasirox
polymorphic forms
triazol
hydroxyphenyl
Prior art date
Application number
MX2009005619A
Other languages
English (en)
Inventor
Michael Mutz
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP06125002A external-priority patent/EP1927591A1/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2009005619A publication Critical patent/MX2009005619A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invención se refiere a las formas cristalinas del ácido 4-[3,5-bis-(2-hidroxi-fenil)-[1,2,4]-triazol-1-il]-benzoico, y a su forma amorfa, a procesos para su preparación, a composiciones que las contienen, y a sus usos para la fabricación de un medicamento para el tratamiento del cuerpo humano.
MX2009005619A 2006-11-29 2007-11-27 Formas poliformicas del deferasirox (icl670a). MX2009005619A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06125002A EP1927591A1 (en) 2006-11-29 2006-11-29 Polymorphic Forms of Deferasirox (ICL670)
EP07112795 2007-07-19
PCT/EP2007/062903 WO2008065123A2 (en) 2006-11-29 2007-11-27 Polymorphic forms of deferasirox ( icl670a)

Publications (1)

Publication Number Publication Date
MX2009005619A true MX2009005619A (es) 2009-06-08

Family

ID=39185764

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005619A MX2009005619A (es) 2006-11-29 2007-11-27 Formas poliformicas del deferasirox (icl670a).

Country Status (11)

Country Link
US (3) US8153672B2 (es)
EP (1) EP2099775A2 (es)
JP (2) JP2010511012A (es)
KR (2) KR20150046369A (es)
AU (1) AU2007327585B2 (es)
BR (1) BRPI0720793A2 (es)
CA (1) CA2670313C (es)
IN (1) IN2009DE02961A (es)
MX (1) MX2009005619A (es)
RU (1) RU2468015C2 (es)
WO (1) WO2008065123A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008065123A2 (en) 2006-11-29 2008-06-05 Novartis Ag Polymorphic forms of deferasirox ( icl670a)
WO2009016359A1 (en) * 2007-07-27 2009-02-05 Pliva Hrvatska D.O.O. New forms of deferasirox
US20110171138A1 (en) * 2008-06-02 2011-07-14 Actavis Group Ptc Ehf Substantially pure deferasirox and processes for the preparation thereof
JP2013512893A (ja) * 2009-12-07 2013-04-18 マピ ファーマ リミテッド デフェラシロクスの調製方法、及びデフェラシロクスの多形体
WO2012069946A1 (en) * 2010-11-24 2012-05-31 Alembic Pharmaceuticals Limited Process for the preparation of deferasirox
US9290452B2 (en) 2012-08-06 2016-03-22 Basf Se Multicomponent crystalline system comprising deferasirox and isonicotinamide and a process for the preparation thereof
GR1009592B (el) 2018-07-03 2019-09-11 Φαρματεν Α.Β.Ε.Ε. Φαρμακευτικο σκευασμα που περιλαμβανει εναν χηλικο παραγοντα συμπλεκτικο του σιδηρου και μεθοδος για την παρασκευη αυτου

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW533205B (en) 1996-06-25 2003-05-21 Novartis Ag Substituted 3,5-diphenyl-l,2,4-triazoles and their pharmaceutical composition
US7563748B2 (en) 2003-06-23 2009-07-21 Cognis Ip Management Gmbh Alcohol alkoxylate carriers for pesticide active ingredients
GB0408078D0 (en) 2004-04-08 2004-05-12 Novartis Ag Organic compounds
RU2346996C2 (ru) 2004-06-29 2009-02-20 ЮРОПИЭН НИКЕЛЬ ПиЭлСи Усовершенствованное выщелачивание основных металлов
EP1853235A1 (en) * 2005-02-10 2007-11-14 Novartis AG Methods for improving drug disposition
CA2608709A1 (en) * 2005-05-31 2006-12-07 Novartis Ag Treatment of liver diseases in which iron plays a role in pathogenesis
WO2008065123A2 (en) * 2006-11-29 2008-06-05 Novartis Ag Polymorphic forms of deferasirox ( icl670a)
EP2108013A2 (en) * 2007-01-29 2009-10-14 Teva Gyógyszergyár Zártköruen Muködo Részvénytársaság Crystalline forms of deferasirox

Also Published As

Publication number Publication date
KR20150046369A (ko) 2015-04-29
AU2007327585A1 (en) 2008-06-05
WO2008065123A2 (en) 2008-06-05
AU2007327585B2 (en) 2011-09-29
US8946272B2 (en) 2015-02-03
EP2099775A2 (en) 2009-09-16
JP2014051517A (ja) 2014-03-20
RU2468015C2 (ru) 2012-11-27
US8153672B2 (en) 2012-04-10
US20130267572A1 (en) 2013-10-10
US20120203007A1 (en) 2012-08-09
BRPI0720793A2 (pt) 2014-03-11
US8436030B2 (en) 2013-05-07
WO2008065123A3 (en) 2008-07-17
RU2009124593A (ru) 2011-01-10
JP2010511012A (ja) 2010-04-08
KR20090085081A (ko) 2009-08-06
CA2670313A1 (en) 2008-06-05
US20100056590A1 (en) 2010-03-04
IN2009DE02961A (es) 2009-07-17
CA2670313C (en) 2013-02-12

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