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MX2009005671A - Forma de dosificacion de nicotina transmucosal oral. - Google Patents

Forma de dosificacion de nicotina transmucosal oral.

Info

Publication number
MX2009005671A
MX2009005671A MX2009005671A MX2009005671A MX2009005671A MX 2009005671 A MX2009005671 A MX 2009005671A MX 2009005671 A MX2009005671 A MX 2009005671A MX 2009005671 A MX2009005671 A MX 2009005671A MX 2009005671 A MX2009005671 A MX 2009005671A
Authority
MX
Mexico
Prior art keywords
dosage form
nicotine
oral transmucosal
nicotine dosage
transmucosal nicotine
Prior art date
Application number
MX2009005671A
Other languages
English (en)
Inventor
Rajendra K Khankari
Vikas Agarwal
Brian Hague
Original Assignee
Cima Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cima Labs Inc filed Critical Cima Labs Inc
Publication of MX2009005671A publication Critical patent/MX2009005671A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La invención descrita en la presente es concerniente con una forma de dosificación sólida transmucosal oral útil en el tratamiento de adicción a nicotina o como sustituto o reemplazo de nicotina. En virtud de la formulación en combinación con nicotina, la invención administra transmucosalmente una cantidad efectiva de nicotina al receptor en tanto que permite la realización y manufactura de tal utilizando un tamaño de forma de dosificación relativa pequeña, conveniente y oralmente confortable (por ejemplo, tableta).
MX2009005671A 2006-12-01 2007-11-20 Forma de dosificacion de nicotina transmucosal oral. MX2009005671A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87212506P 2006-12-01 2006-12-01
US87217706P 2006-12-01 2006-12-01
PCT/US2007/024218 WO2008069921A2 (en) 2006-12-01 2007-11-20 Oral transmucosal nicotine dosage form

Publications (1)

Publication Number Publication Date
MX2009005671A true MX2009005671A (es) 2009-06-08

Family

ID=39365631

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005671A MX2009005671A (es) 2006-12-01 2007-11-20 Forma de dosificacion de nicotina transmucosal oral.

Country Status (9)

Country Link
US (2) US20080131508A1 (es)
EP (1) EP2101744A2 (es)
JP (1) JP2010511611A (es)
AU (1) AU2007328373A1 (es)
BR (1) BRPI0719428A2 (es)
CA (1) CA2670886A1 (es)
IL (1) IL198753A0 (es)
MX (1) MX2009005671A (es)
WO (1) WO2008069921A2 (es)

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US6974590B2 (en) 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
ATE359075T1 (de) 2002-12-20 2007-05-15 Niconovum Ab Chemisch und physikalisch stabiles teilchenförmiges material enthaltend nikotin und microcrystalline cellulose
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
AU2007224584A1 (en) 2006-03-16 2007-09-20 Niconovum Ab Improved snuff composition
AU2007328373A1 (en) * 2006-12-01 2008-06-12 Cima Labs Inc. Oral transmucosal nicotine dosage form
US20090214442A1 (en) * 2006-12-01 2009-08-27 Cephalon, Inc. Oral Transmucosal Nicotine Dosage Form
GB2468424B (en) * 2007-04-02 2011-11-09 Parkinson S Inst Methods and compositions for reduction of side effects of therapeutic treatments
CA2699806A1 (en) * 2007-09-18 2009-03-26 Niconovum Ab Stable chewing gum compositions comprising maltitol and providing rapid release of nicotine
US20100018540A1 (en) * 2008-07-28 2010-01-28 David James Doolittle Smokeless tobacco products and processes
US8833378B2 (en) * 2008-09-17 2014-09-16 Niconovum Ab Process for preparing snuff composition
US8506936B2 (en) * 2008-11-25 2013-08-13 Watson Laboratories, Inc. Stabilized nicotine chewing gum
EP2213181A1 (en) * 2009-01-28 2010-08-04 Philip Morris Products S.A. Smokeless dissolvable compressed tobacco product
US20110268809A1 (en) * 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US9675102B2 (en) * 2010-09-07 2017-06-13 R. J. Reynolds Tobacco Company Smokeless tobacco product comprising effervescent composition
US20130017259A1 (en) 2011-07-06 2013-01-17 The Parkinson's Institute Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients
US9907748B2 (en) * 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
WO2015051041A1 (en) * 2013-10-02 2015-04-09 Park Andrew Chunkil Smoking cessation device
CA2974324A1 (en) 2015-01-28 2016-08-04 Zita S. Netzel Drug delivery methods and systems
WO2016145373A1 (en) 2015-03-12 2016-09-15 Chrono Therapeutics Inc. Craving input and support system
EP3565617A1 (en) 2017-01-06 2019-11-13 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
EP3720497A1 (en) 2017-12-08 2020-10-14 Fertin Pharma A/S High nicotine concentration
JP7278281B2 (ja) * 2017-12-08 2023-05-19 フェルティン ファルマ アー／エス ニコチン錠
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems
CA3119992A1 (en) 2018-11-16 2020-05-22 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
GB2586301B (en) * 2020-04-07 2021-08-25 Splash Tm Gmbh Stable-Foam inhalation Device and Cartridge

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US5855908A (en) * 1984-05-01 1999-01-05 University Of Utah Research Foundation Non-dissolvable drug-containing dosage-forms for use in the transmucosal delivery of a drug to a patient
US4863737A (en) * 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
US5783207A (en) * 1985-05-01 1998-07-21 University Of Utah Research Foundation Selectively removable nicotine-containing dosage form for use in the transmucosal delivery of nicotine
US5132114A (en) * 1985-05-01 1992-07-21 University Of Utah Research Foundation Compositions and methods of manufacture of compressed powder medicaments
US5288497A (en) * 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
US5234957A (en) * 1991-02-27 1993-08-10 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5824334A (en) * 1989-09-05 1998-10-20 University Of Utah Research Foundation Tobacco substitute
US5178878A (en) * 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles
US5298261A (en) * 1992-04-20 1994-03-29 Oregon Freeze Dry, Inc. Rapidly distintegrating tablet
US5846963A (en) * 1995-06-07 1998-12-08 University Of Utah Research Foundation Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome
US5503846A (en) * 1993-03-17 1996-04-02 Cima Labs, Inc. Base coated acid particles and effervescent formulation incorporating same
US5549906A (en) * 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
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US5595761A (en) * 1994-01-27 1997-01-21 The Board Of Regents Of The University Of Oklahoma Particulate support matrix for making a rapidly dissolving tablet
US6165495A (en) * 1994-04-29 2000-12-26 Blankenship; Mildred Drug delivery system
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DE19757059A1 (de) * 1997-12-20 1999-07-01 Merz & Co Gmbh & Co Balneologische Brausetablette, Verfahren zu ihrer Herstellung und ihre Verwendung
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US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US6974590B2 (en) * 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US6358060B2 (en) * 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
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US7858121B2 (en) * 2003-12-31 2010-12-28 Cima Labs, Inc. Effervescent oral fentanyl dosage form and methods of administering fentanyl
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AU2004311879B2 (en) * 2003-12-31 2010-08-05 Phoenix Labs Unlimited Company Effervescent oral opiate dosage form
AU2007328373A1 (en) * 2006-12-01 2008-06-12 Cima Labs Inc. Oral transmucosal nicotine dosage form
US20090214442A1 (en) * 2006-12-01 2009-08-27 Cephalon, Inc. Oral Transmucosal Nicotine Dosage Form

Also Published As

Publication number Publication date
WO2008069921A3 (en) 2008-10-30
AU2007328373A1 (en) 2008-06-12
IL198753A0 (en) 2010-02-17
US20080131508A1 (en) 2008-06-05
CA2670886A1 (en) 2008-06-12
JP2010511611A (ja) 2010-04-15
EP2101744A2 (en) 2009-09-23
US20110206621A1 (en) 2011-08-25
BRPI0719428A2 (pt) 2014-02-25
WO2008069921A2 (en) 2008-06-12

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Legal Events

Date Code Title Description
HH Correction or change in general
FA Abandonment or withdrawal