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MX2009003654A - Sistema de suministro por liberacion controlada para la aplicacion nasal de neurotransmisores. - Google Patents

Sistema de suministro por liberacion controlada para la aplicacion nasal de neurotransmisores.

Info

Publication number
MX2009003654A
MX2009003654A MX2009003654A MX2009003654A MX2009003654A MX 2009003654 A MX2009003654 A MX 2009003654A MX 2009003654 A MX2009003654 A MX 2009003654A MX 2009003654 A MX2009003654 A MX 2009003654A MX 2009003654 A MX2009003654 A MX 2009003654A
Authority
MX
Mexico
Prior art keywords
neurotransmitters
container
partly
brain
lipophilic
Prior art date
Application number
MX2009003654A
Other languages
English (en)
Inventor
Claudia Mattern
Original Assignee
M & P Patent Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by M & P Patent Ag filed Critical M & P Patent Ag
Publication of MX2009003654A publication Critical patent/MX2009003654A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Esta invención se refiere a una formulación galénica de gel para la administración nasal de neurotransmisores tales como dopamina. El sistema lipofílico o en parte lipofílico especial de la invención conduce a una alta biodisponibilidad del ingrediente activo en el plasma y el cerebro causado por los niveles continuos en el suero y/o dirige parcialmente el transporte de la nariz al cerebro.
MX2009003654A 2006-10-04 2007-09-27 Sistema de suministro por liberacion controlada para la aplicacion nasal de neurotransmisores. MX2009003654A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82810906P 2006-10-04 2006-10-04
PCT/EP2007/008409 WO2008040488A1 (en) 2006-10-04 2007-09-27 Controlled release delivery system for nasal application of neurotransmitters

Publications (1)

Publication Number Publication Date
MX2009003654A true MX2009003654A (es) 2009-04-22

Family

ID=38799348

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009003654A MX2009003654A (es) 2006-10-04 2007-09-27 Sistema de suministro por liberacion controlada para la aplicacion nasal de neurotransmisores.

Country Status (19)

Country Link
US (4) US20090227550A1 (es)
EP (1) EP2068825B1 (es)
JP (1) JP5248510B2 (es)
KR (1) KR101307133B1 (es)
CN (1) CN101600417B (es)
AT (1) ATE496617T1 (es)
AU (1) AU2007304471B2 (es)
BR (1) BRPI0717509B8 (es)
CA (1) CA2664427C (es)
DE (1) DE602007012276D1 (es)
DK (1) DK2068825T3 (es)
ES (1) ES2358619T3 (es)
MX (1) MX2009003654A (es)
NO (1) NO339802B1 (es)
PL (1) PL2068825T3 (es)
PT (1) PT2068825E (es)
RU (1) RU2480208C2 (es)
WO (1) WO2008040488A1 (es)
ZA (1) ZA200902902B (es)

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EP1957113A4 (en) * 2005-11-21 2011-11-09 Medivas Llc POLYMER PARTICLES FOR THE OUTPUT OF MACROMOLECULES AND METHOD OF APPLICATION THEREFOR
RU2480208C2 (ru) 2006-10-04 2013-04-27 М Унд П Патент Акциенгезелльшафт Система доставки с контролируемым высвобождением для назального применения нейротрансмиттеров

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NO339802B1 (no) 2017-02-06
KR101307133B1 (ko) 2013-09-12
US9801834B2 (en) 2017-10-31
CA2664427C (en) 2012-06-05
US9186320B2 (en) 2015-11-17
CA2664427A1 (en) 2008-04-10
DE602007012276D1 (de) 2011-03-10
RU2480208C2 (ru) 2013-04-27
US20160089347A1 (en) 2016-03-31
HK1137658A1 (en) 2010-08-06
KR20090098958A (ko) 2009-09-18
CN101600417B (zh) 2012-05-30
EP2068825B1 (en) 2011-01-26
CN101600417A (zh) 2009-12-09
PL2068825T3 (pl) 2011-06-30
NO20091695L (no) 2009-06-23
BRPI0717509B1 (pt) 2019-11-26
PT2068825E (pt) 2011-02-11
BRPI0717509A2 (pt) 2016-05-17
ES2358619T3 (es) 2011-05-12
ZA200902902B (en) 2010-07-28
EP2068825A1 (en) 2009-06-17
WO2008040488A1 (en) 2008-04-10
ATE496617T1 (de) 2011-02-15
AU2007304471B2 (en) 2012-09-06
RU2009116609A (ru) 2010-11-10
BRPI0717509B8 (pt) 2021-05-25
US20090227550A1 (en) 2009-09-10
JP2010505778A (ja) 2010-02-25
JP5248510B2 (ja) 2013-07-31
US20120009249A1 (en) 2012-01-12
DK2068825T3 (da) 2011-05-16
US20180200203A1 (en) 2018-07-19

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