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MX2009003571A - Polimorfo b de n-{2-fluoro-5-[3-(tiofen-2-carbonil)-pirazolo[1,5-a ]pirimidin-7-il]-fenil}-n-metil-acetamida. - Google Patents

Polimorfo b de n-{2-fluoro-5-[3-(tiofen-2-carbonil)-pirazolo[1,5-a ]pirimidin-7-il]-fenil}-n-metil-acetamida.

Info

Publication number
MX2009003571A
MX2009003571A MX2009003571A MX2009003571A MX2009003571A MX 2009003571 A MX2009003571 A MX 2009003571A MX 2009003571 A MX2009003571 A MX 2009003571A MX 2009003571 A MX2009003571 A MX 2009003571A MX 2009003571 A MX2009003571 A MX 2009003571A
Authority
MX
Mexico
Prior art keywords
pyrazolo
pyrimidin
acetamide
thiophene
fluoro
Prior art date
Application number
MX2009003571A
Other languages
English (en)
Inventor
Albert Palomer
Antonio Guglietta
Luis Anglada
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37789824&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009003571(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of MX2009003571A publication Critical patent/MX2009003571A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención se refiere a un nuevo polimorfo de N-{2-fluoro-5-[3(tiofen-2-carbonil)-pirazolo[1,5-a]pirimidin-7-il ]-fenil}-N-metil-acetamida, a procedimientos para su preparación, a su uso como medicamento, su uso en la fabricación de un medicamento y a composiciones farmacéuticas que comprenden el nuevo polimorfo.
MX2009003571A 2006-10-11 2007-10-10 Polimorfo b de n-{2-fluoro-5-[3-(tiofen-2-carbonil)-pirazolo[1,5-a ]pirimidin-7-il]-fenil}-n-metil-acetamida. MX2009003571A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85074306P 2006-10-11 2006-10-11
EP06122138A EP1918290A1 (en) 2006-10-11 2006-10-11 Polymorph B of N-{2-Fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a] pyrimidin-7-yl]-phenyl}-N-methyl-acetamide
PCT/EP2007/060797 WO2008043800A1 (en) 2006-10-11 2007-10-10 Polymorph b of n-{2-fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a] pyrimidin-7-yl]-phenyl}-n-methyl-acetamide

Publications (1)

Publication Number Publication Date
MX2009003571A true MX2009003571A (es) 2009-04-14

Family

ID=37789824

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009003571A MX2009003571A (es) 2006-10-11 2007-10-10 Polimorfo b de n-{2-fluoro-5-[3-(tiofen-2-carbonil)-pirazolo[1,5-a ]pirimidin-7-il]-fenil}-n-metil-acetamida.

Country Status (21)

Country Link
US (2) US8039476B2 (es)
EP (2) EP1918290A1 (es)
JP (1) JP5171831B2 (es)
KR (1) KR101418624B1 (es)
CN (1) CN101622257B (es)
AR (1) AR063231A1 (es)
AU (1) AU2007306319B2 (es)
BR (1) BRPI0717833A2 (es)
CA (1) CA2666653C (es)
CL (1) CL2007002928A1 (es)
DK (1) DK2081935T3 (es)
ES (1) ES2637137T3 (es)
MX (1) MX2009003571A (es)
NO (1) NO342008B1 (es)
PL (1) PL2081935T3 (es)
PT (1) PT2081935T (es)
RU (1) RU2413729C2 (es)
SI (1) SI2081935T1 (es)
TW (1) TWI391392B (es)
UY (1) UY30637A1 (es)
WO (1) WO2008043800A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1921079A1 (en) * 2006-11-08 2008-05-14 Ferrer Internacional, S.A. Amorphous form of N-{2-Fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a] pyrimidin-7-yl]-phenyl}-N-methyl-acetamide
EP2261999B1 (en) * 2008-03-31 2019-03-27 Kyocera Corporation Solar cell element and solar cell module
IT1391113B1 (it) * 2008-09-30 2011-11-18 Dipharma Francis Srl Procedimento per la preparazione di azelnidipina cristallina

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US399621A (en) * 1889-03-12 Canning-house truck
ZA831407B (en) * 1982-03-25 1983-11-30 Erba Farmitalia Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation
US6399621B1 (en) * 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
EP1477169A1 (en) * 1999-09-02 2004-11-17 Neurocrine Biosciences, Inc. Reactions of polymorphs of N-methyl-N-(3-(3-(2-thienylcarbonyl)-pyrazol-(1,5-alpha)-pyrimidin-7-yl)phenyl)acetamide
MXPA05002251A (es) * 2002-08-26 2005-06-08 Neurocrine Biosciences Inc Polimorfo novedoso del n- metil -n- (3- {3-[2- tienilcarbonil] -pirazol -[1, 5-(alfa)] -pirimidina- 7-yl} fenil) acetamida y composiciones y metodos relacionados.
AR053979A1 (es) * 2004-10-18 2007-05-30 Neurocrine Biosciences Inc Hidrato de n-metil-n-(3-[3-[2-tienilcarbonil]-pirazol-[1,5-a-pirimidin-7-il]fenil)acetamida y procesos de obtencion
EP1736475A1 (en) * 2005-06-21 2006-12-27 Ferrer Internacional, S.A. Halogenated pyrazolo[1,5-a]pyrimidines, processes, uses, compositions and intermediates

Also Published As

Publication number Publication date
CL2007002928A1 (es) 2008-05-09
US20110224234A1 (en) 2011-09-15
KR101418624B1 (ko) 2014-07-15
PL2081935T3 (pl) 2018-04-30
CN101622257A (zh) 2010-01-06
TWI391392B (zh) 2013-04-01
US8273753B2 (en) 2012-09-25
US20100087451A1 (en) 2010-04-08
PT2081935T (pt) 2017-08-29
TW200827360A (en) 2008-07-01
US8039476B2 (en) 2011-10-18
AU2007306319A1 (en) 2008-04-17
RU2009117716A (ru) 2010-11-20
AU2007306319B2 (en) 2012-12-06
KR20090077796A (ko) 2009-07-15
UY30637A1 (es) 2008-05-02
EP1918290A1 (en) 2008-05-07
RU2413729C2 (ru) 2011-03-10
JP5171831B2 (ja) 2013-03-27
ES2637137T3 (es) 2017-10-11
CA2666653A1 (en) 2008-04-17
AR063231A1 (es) 2009-01-14
EP2081935A1 (en) 2009-07-29
NO20091625L (no) 2009-05-07
BRPI0717833A2 (pt) 2014-06-10
CA2666653C (en) 2014-12-30
CN101622257B (zh) 2013-03-27
SI2081935T1 (sl) 2017-12-29
DK2081935T3 (en) 2017-09-04
EP2081935B1 (en) 2017-05-24
NO342008B1 (no) 2018-03-12
JP2010505914A (ja) 2010-02-25
WO2008043800A1 (en) 2008-04-17

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