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MX2008015892A - Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacion de los mismos. - Google Patents

Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacion de los mismos.

Info

Publication number
MX2008015892A
MX2008015892A MX2008015892A MX2008015892A MX2008015892A MX 2008015892 A MX2008015892 A MX 2008015892A MX 2008015892 A MX2008015892 A MX 2008015892A MX 2008015892 A MX2008015892 A MX 2008015892A MX 2008015892 A MX2008015892 A MX 2008015892A
Authority
MX
Mexico
Prior art keywords
von willebrand
factor
willebrand factor
complex
concentrate
Prior art date
Application number
MX2008015892A
Other languages
English (en)
Inventor
Debart Pere Ristol
Tomas Maria Mercedes Faro
Nieto Juan Ignacio Jorquera
Original Assignee
Grifols Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39316136&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2008015892(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Grifols Sa filed Critical Grifols Sa
Publication of MX2008015892A publication Critical patent/MX2008015892A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0017—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

El procedimiento se caracteriza por la preparación de una solución de Factor von Willebrand o de complejo de Factor VIII/ Factor von Willebrand que contiene FVW a una concentración de hasta 12 UI FVWRCo/ml y una proporción entre Factor von Willebrand/ Factor VIII superior o igual a 0,4; y proceder a continuación a la nanofiltración de la solución preparada en a) mediante un filtro de tamaño de poro menor de 35 nanómetros.
MX2008015892A 2008-01-08 2008-12-11 Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacion de los mismos. MX2008015892A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200800021A ES2298096B1 (es) 2008-01-08 2008-01-08 Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos.

Publications (1)

Publication Number Publication Date
MX2008015892A true MX2008015892A (es) 2009-07-07

Family

ID=39316136

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008015892A MX2008015892A (es) 2008-01-08 2008-12-11 Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacion de los mismos.

Country Status (16)

Country Link
US (2) US8354505B2 (es)
EP (1) EP2078730B9 (es)
JP (1) JP4976366B2 (es)
CN (1) CN101480490B (es)
AR (1) AR072441A1 (es)
AT (1) ATE509031T1 (es)
AU (1) AU2008255137C1 (es)
BR (1) BRPI0900057B8 (es)
CA (1) CA2645701C (es)
CL (1) CL2009000022A1 (es)
ES (2) ES2298096B1 (es)
MX (1) MX2008015892A (es)
NZ (1) NZ573400A (es)
PL (1) PL2078730T3 (es)
PT (1) PT2078730E (es)
RU (1) RU2417096C2 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2861395B1 (fr) * 2003-10-23 2006-02-17 Lab Francais Du Fractionnement Facteur viii viralement securise a faible teneur en multimeres superieurs
AU2008345135C1 (en) 2007-12-28 2015-04-30 Takeda Pharmaceutical Company Limited Recombinant VWF formulations
US11197916B2 (en) 2007-12-28 2021-12-14 Takeda Pharmaceutical Company Limited Lyophilized recombinant VWF formulations
CN103919736A (zh) 2008-10-21 2014-07-16 巴克斯特国际公司 冻干的重组vwf配方
EP3858375B1 (en) * 2011-06-10 2024-03-20 Takeda Pharmaceutical Company Limited Treatment of coagulation disease by administration of recombinant vwf
US9359397B2 (en) 2011-06-24 2016-06-07 Asahi Kasei Medical Co., Ltd. Method for manufacturing protein drug
HRP20191920T1 (hr) * 2012-01-12 2020-01-10 Bioverativ Therapeutics Inc. Kimerni polipeptidi faktora viii i njihova uporaba
JP2015515482A (ja) 2012-04-24 2015-05-28 ノヴォ ノルディスク アー／エス 血友病の治療に適する化合物
US10246485B2 (en) 2013-11-08 2019-04-02 Csl Limited Method to concentrate von willebrand factor or complexes thereof
BR112016026842A2 (pt) * 2014-06-06 2017-12-12 Octapharma Ag preparação compreendendo fator viii e peptídeos de fator de von willebrand
CN104804078B (zh) * 2015-05-05 2019-01-04 广东卫伦生物制药有限公司 人体血清凝血因子ⅷ中的病毒过滤方法
CN111183151B (zh) 2017-06-23 2024-06-07 武田药品工业株式会社 因子viii亚种的纯化
CN110997015A (zh) * 2017-08-23 2020-04-10 德国杰特贝林生物制品有限公司 用于von Willebrand因子的病毒过滤的方法
CA3228445A1 (en) 2021-08-11 2023-02-16 Salvador Grancha Gamon Method for producing human plasma-derived factor viii / von willebrand factor and composition obtained

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110907A (en) * 1989-08-01 1992-05-05 Alpha Therapeutic Corporation Factor viii complex purification using heparin affinity chromatography
US5288853A (en) 1992-04-30 1994-02-22 Alpha Therapeutic Corporation Factor viii purification process
EP0860444A1 (en) * 1997-02-24 1998-08-26 Stichting Centraal Laboratorium van de Bloedtransfusiedienst van het Nederlandse Rode Kruis (CLB) Method for removing viruses from a protein solution
AT406373B (de) 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
AT405485B (de) * 1997-05-28 1999-08-25 Immuno Ag Eine das vwf-propeptid enthaltende pharmazeutische präparation
FR2772381B1 (fr) * 1997-12-15 2001-06-08 Lab Francais Du Fractionnement Procede de preparation par filtration d'une solution de facteur viii securisee viralement
FR2861395B1 (fr) * 2003-10-23 2006-02-17 Lab Francais Du Fractionnement Facteur viii viralement securise a faible teneur en multimeres superieurs
RU2256464C1 (ru) * 2004-03-12 2005-07-20 Общество с ограниченной ответственностью "БиоГениус" Способ получения с1-эстеразного ингибитора человека и продукт для использования в медицине
FR2874216B1 (fr) * 2004-08-16 2006-11-03 Lab Francais Du Fractionnement Procede de preparation d'un concentre de facteur von willebrand (fvw) par voie chromatographique et concentre de fvw susceptible d'etre ainsi obtenu

Also Published As

Publication number Publication date
JP4976366B2 (ja) 2012-07-18
PL2078730T3 (pl) 2011-10-31
AU2008255137B2 (en) 2011-04-07
US20090176709A1 (en) 2009-07-09
NZ573400A (en) 2010-02-26
ES2298096B1 (es) 2009-01-01
AU2008255137C1 (en) 2015-08-27
US20110275570A1 (en) 2011-11-10
CA2645701C (en) 2013-09-17
PT2078730E (pt) 2011-07-14
AU2008255137A1 (en) 2009-07-23
ES2298096A1 (es) 2008-05-01
US8354505B2 (en) 2013-01-15
BRPI0900057B1 (pt) 2021-03-23
CN101480490A (zh) 2009-07-15
CL2009000022A1 (es) 2009-11-20
EP2078730B1 (en) 2011-05-11
JP2009161528A (ja) 2009-07-23
RU2417096C2 (ru) 2011-04-27
CA2645701A1 (en) 2009-07-08
EP2078730B9 (en) 2011-12-21
BRPI0900057A2 (pt) 2009-09-22
ATE509031T1 (de) 2011-05-15
RU2008151957A (ru) 2010-07-10
CN101480490B (zh) 2013-05-29
HK1129075A1 (en) 2009-11-20
ES2363827T3 (es) 2011-08-17
BRPI0900057B8 (pt) 2021-06-29
AR072441A1 (es) 2010-09-01
EP2078730A1 (en) 2009-07-15

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