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MX2008015660A - Reservorios de titania nanoestructurados por el metodo sol-gel para uso en la liberacion controlada de farmacos en el sistema nervioso central y metodos de sintesis. - Google Patents

Reservorios de titania nanoestructurados por el metodo sol-gel para uso en la liberacion controlada de farmacos en el sistema nervioso central y metodos de sintesis.

Info

Publication number
MX2008015660A
MX2008015660A MX2008015660A MX2008015660A MX2008015660A MX 2008015660 A MX2008015660 A MX 2008015660A MX 2008015660 A MX2008015660 A MX 2008015660A MX 2008015660 A MX2008015660 A MX 2008015660A MX 2008015660 A MX2008015660 A MX 2008015660A
Authority
MX
Mexico
Prior art keywords
drugs
sol
synthesis
reservoirs
nervous system
Prior art date
Application number
MX2008015660A
Other languages
English (en)
Inventor
Tessy Maria Lopez Goerne
Original Assignee
Univ Autonoma Metropolitana
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Autonoma Metropolitana filed Critical Univ Autonoma Metropolitana
Publication of MX2008015660A publication Critical patent/MX2008015660A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/026—Ceramic or ceramic-like structures, e.g. glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00—Silicon; Compounds thereof
    • C01B33/113—Silicon oxides; Hydrates thereof
    • C01B33/12—Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • C01B33/14—Colloidal silica, e.g. dispersions, gels, sols
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G23/00—Compounds of titanium
    • C01G23/04—Oxides; Hydroxides
    • C01G23/047—Titanium dioxide
    • C01G23/053—Producing by wet processes, e.g. hydrolysing titanium salts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/80—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
    • C01P2002/82—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by IR- or Raman-data
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/01—Particle morphology depicted by an image
    • C01P2004/03—Particle morphology depicted by an image obtained by SEM
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/01—Particle morphology depicted by an image
    • C01P2004/04—Particle morphology depicted by an image obtained by TEM, STEM, STM or AFM
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/12—Surface area
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/831—Of specified ceramic or electrically insulating compositions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Environmental & Geological Engineering (AREA)
  • Psychology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Geology (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ceramic Engineering (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)

Abstract

La invención está relacionada con un reservorio de titania nanoestructurado formado por la vía sol-gel y su síntesis, que es biocompatible con el tejido cerebral. La distribución del tamaño de partícula, tamaño del cristal y la extensión de la fase cristalina, distribución de anatasa, brokite y rutile puede ser completamente controlada. Este dispositivo puede ser usado para contener fármacos neurológicos. Puede ser insertado directamente dentro del tejido cerebral para el propósito de controlar el tiempo de liberación del fármaco a lo largo de un periodo de tiempo de entre seis meses tres años.
MX2008015660A 2006-06-06 2006-06-06 Reservorios de titania nanoestructurados por el metodo sol-gel para uso en la liberacion controlada de farmacos en el sistema nervioso central y metodos de sintesis. MX2008015660A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2006/001725 WO2007141590A1 (en) 2006-06-06 2006-06-06 Sol-gel nanostructured titania reservoirs for use in the controlled release of drugs in the central nervous system and method of synthesis

Publications (1)

Publication Number Publication Date
MX2008015660A true MX2008015660A (es) 2009-04-02

Family

ID=37835067

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008015660A MX2008015660A (es) 2006-06-06 2006-06-06 Reservorios de titania nanoestructurados por el metodo sol-gel para uso en la liberacion controlada de farmacos en el sistema nervioso central y metodos de sintesis.

Country Status (6)

Country Link
US (2) US8343514B2 (es)
EP (1) EP2020987B1 (es)
JP (1) JP5436207B2 (es)
AU (1) AU2006344099B2 (es)
MX (1) MX2008015660A (es)
WO (1) WO2007141590A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ573300A0 (en) 2000-02-21 2000-03-16 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
WO2010150036A1 (en) * 2009-06-24 2010-12-29 Universidad Autonoma Metropolitana - Xochimilco Sol-gel nanostructured and biocompatible platinum-titania and platinum- silica biocatalysts nanostructured and biocompatible for use in cancer treatment
MX339086B (es) 2013-06-20 2016-05-09 Inmolecule Internat Ltd Nanomaterial de dioxido de titanio nanoparticulado modificado con grupos funcionales y con extractos citricos adsorbidos en la superficie para la eliminacion de amplio espectro de microorganismos.
AU2014289765B2 (en) 2013-07-11 2019-05-09 Tasly Pharmaceutical Group Co., Ltd. Preparation method for traditional Chinese medicine micro drop pill and traditional Chinese medicine micro drop pill prepared by using the method
HUE058040T2 (hu) 2013-07-11 2022-06-28 Tasly Pharmaceutical Group Co Hagyományos kínai gyógyászati kompozíció, és ennek elkészítése és alkalmazása
EP3020407B1 (en) 2013-07-11 2025-04-23 Tasly Pharmaceutical Group Co., Ltd. Traditional chinese medicine composition, and preparation and application thereof
CN104418744B (zh) 2013-08-29 2017-03-01 天士力制药集团股份有限公司 一种新的丹酚酸化合物t、其制备方法和用途
MX360196B (es) 2013-09-25 2018-10-11 Mexicano Inst Petrol Catalizador de titania nanoestructurada de acidez estabilizada y proceso de obtencion.
WO2019016723A2 (en) * 2017-07-20 2019-01-24 GÓMEZ-LÓPEZ, Wenceslao NANOSTRUCTURED AND BIOCOMPATIBLE BIOCATALYSTS FOR TREATING CANCER

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591453A (en) * 1994-07-27 1997-01-07 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses
RU2208582C2 (ru) * 1996-05-29 2003-07-20 Биоксид Ой Средство для доставки, обеспечивающее непрерывное и/или регулируемое высвобождение биологически активных агентов
US6117814A (en) * 1998-02-10 2000-09-12 Exxon Research And Engineering Co. Titania catalysts their preparation and use in fischer-tropsch synthesis
DE19860511A1 (de) 1998-12-28 2000-07-13 Fraunhofer Ges Forschung Verfahren zur Herstellung eines mikrostrukturierten SiO¶2¶/TiO¶2¶-Schichtsystems
IL138990A0 (en) * 1999-02-12 2001-11-25 Biostream Inc Matrices for drug delivery and methods for making and using the same
AUPQ573300A0 (en) * 2000-02-21 2000-03-16 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
FI20010523A0 (fi) * 2001-03-16 2001-03-16 Yli Urpo Antti Soolien, geelien ja niiden seosten käsittely
US7744644B2 (en) * 2004-03-19 2010-06-29 Boston Scientific Scimed, Inc. Medical articles having regions with polyelectrolyte multilayer coatings for regulating drug release

Also Published As

Publication number Publication date
AU2006344099B2 (en) 2013-02-28
US8343514B2 (en) 2013-01-01
US20100233230A1 (en) 2010-09-16
WO2007141590A1 (en) 2007-12-13
EP2020987A1 (en) 2009-02-11
JP2009539819A (ja) 2009-11-19
US20130095164A1 (en) 2013-04-18
JP5436207B2 (ja) 2014-03-05
AU2006344099A1 (en) 2007-12-13
EP2020987B1 (en) 2013-10-30

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