MX2008001794A - Proceso para la sintesis de mandipropamida y derivados de la misma. - Google Patents
Proceso para la sintesis de mandipropamida y derivados de la misma.Info
- Publication number
- MX2008001794A MX2008001794A MX2008001794A MX2008001794A MX2008001794A MX 2008001794 A MX2008001794 A MX 2008001794A MX 2008001794 A MX2008001794 A MX 2008001794A MX 2008001794 A MX2008001794 A MX 2008001794A MX 2008001794 A MX2008001794 A MX 2008001794A
- Authority
- MX
- Mexico
- Prior art keywords
- carbon atoms
- sup
- sub
- compound
- formula
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- KWLVWJPJKJMCSH-UHFFFAOYSA-N 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Chemical compound C1=C(OCC#C)C(OC)=CC(CCNC(=O)C(OCC#C)C=2C=CC(Cl)=CC=2)=C1 KWLVWJPJKJMCSH-UHFFFAOYSA-N 0.000 title 1
- 239000005804 Mandipropamid Substances 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 4
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 125000000304 alkynyl group Chemical group 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000005092 alkenyloxycarbonyl group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000005133 alkynyloxy group Chemical group 0.000 abstract 1
- 125000005225 alkynyloxycarbonyl group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 125000004995 haloalkylthio group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/04—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C251/10—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
- C07C251/16—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/37—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by etherified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se describe un proceso para la preparacion de un compuesto de la formula (I) en donde: R es un grupo alquinilo; R1 es alquilo, alquenilo, alquinilo, cicloalquilo, cicloalquil-alquil, fenilo y fenilalquilo, esto es posible a su vez para que todos los grupos anteriores lleven uno o mas atomos de halogeno identicos o diferentes; alcoxi; alqueniloxi; alquiniloxi; alcoxialquilo; haloalcoxi; alquiltio; haloalquiltio; alquilsulfonilo; formilo; alcanoilo; hidroxi; halogeno; ciano; nitro; amino; alquilamino; dialquilamino; carboxilo; alcoxicarbonilo; alqueniloxicarbonilo; o alquiniloxicarbonilo; y n es un entero de 0 a 3, el proceso comprende (i) la reaccion de un compuesto de la formula (III) en donde R, R1 y n son de conformidad con lo definido aqui anteriormente; m y m' son independientemente 0 o 1; cuando m y m' son ambos 0, A es un grupo alquilo, alquenilo o alquinilo (que tiene convenientemente hasta ocho atomos de carbono), opcionalmente substituido por uno o mas grupos seleccionados independientemente de halogeno, hidroxi, alcoxi, dialquilamino C1-4 o ciano; cuando uno de m y m' es 0 y el otro es 1, A es un grupo alcanodiilo, alquenodiilo o alquinodiilo que contiene por lo menos dos atomos de carbono (y que tiene convenientemente hasta ocho atomos de carbono), opcionalmente substituidos por uno o mas grupos seleccionados independientemente de halogeno, hidroxi, alcoxi, dialquilamino C1-4 o ciano; cuando m y el m' son ambos 1, A es un alcanotriilo, alquenotriilo o un grupo alquinotriilo que contiene por lo menos tres atomos de carbono (y que tiene convenientemente hasta ocho atomos de carbono), substituidos opcionalmente por uno o mas grupos seleccionados independientemente de halogeno, hidroxi, alcoxi, dialquilamino C1-4 o ciano; y en donde si el grupo A contiene tres o mas atomos de carbono, uno o mas de los atomos de carbono cada uno opcionalmente puede ser substituido por un atomo de oxigeno, siempre que hay por lo menos un atomo de carbono entre cualquiera de los dos atomos de oxigeno en la molecula, con un compuesto de la formula (IV) para dar un compuesto de formula (II) en donde R, R1 y n son de conformidad con lo definido aqui anteriormente, y (ii) la reaccion de un compuesto de la formula (II) con (ver formula), en donde L es un grupo de salida, para dar el compuesto de la formula (I) de conformidad con lo definido aqui anteriormente.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0516705.1A GB0516705D0 (en) | 2005-08-15 | 2005-08-15 | Process |
| PCT/GB2006/002946 WO2007020381A2 (en) | 2005-08-15 | 2006-08-08 | Process for the synthesis of mandipropamid and derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008001794A true MX2008001794A (es) | 2008-04-07 |
Family
ID=35098316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008001794A MX2008001794A (es) | 2005-08-15 | 2006-08-08 | Proceso para la sintesis de mandipropamida y derivados de la misma. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US8129560B2 (es) |
| EP (1) | EP1919857B1 (es) |
| JP (1) | JP5350790B2 (es) |
| KR (1) | KR101305928B1 (es) |
| CN (1) | CN101243040B (es) |
| AR (2) | AR057741A1 (es) |
| AU (1) | AU2006281293B2 (es) |
| BR (1) | BRPI0616593B1 (es) |
| CA (1) | CA2619435C (es) |
| CR (1) | CR9710A (es) |
| EC (1) | ECSP088183A (es) |
| ES (1) | ES2572137T3 (es) |
| GB (1) | GB0516705D0 (es) |
| GT (1) | GT200600369A (es) |
| HN (1) | HN2006029142A (es) |
| HU (1) | HUE028929T2 (es) |
| IL (3) | IL188919A (es) |
| MX (1) | MX2008001794A (es) |
| MY (1) | MY150654A (es) |
| NZ (1) | NZ574781A (es) |
| PL (1) | PL1919857T3 (es) |
| RU (1) | RU2470914C9 (es) |
| TW (2) | TWI428314B (es) |
| UA (1) | UA90810C2 (es) |
| WO (1) | WO2007020381A2 (es) |
| ZA (1) | ZA200800691B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0808764D0 (en) * | 2008-05-14 | 2008-06-18 | Syngenta Ltd | Process |
| JP5747625B2 (ja) | 2011-04-12 | 2015-07-15 | 住友化学株式会社 | マンデロニトリル化合物の製造方法 |
| WO2013113773A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
| WO2013113776A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
| WO2013113791A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
| WO2013113778A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
| WO2013113716A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
| JP2015511940A (ja) | 2012-02-03 | 2015-04-23 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | 殺菌性ピリミジン化合物 |
| CA2862346A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
| WO2013113720A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
| CN110204556B (zh) * | 2019-07-16 | 2020-09-18 | 重庆医药高等专科学校 | (rs)-甲氧基头孢西丁的制备方法 |
| WO2023044364A1 (en) | 2021-09-15 | 2023-03-23 | Enko Chem, Inc. | Protoporphyrinogen oxidase inhibitors |
| EP4633371A1 (en) | 2022-12-16 | 2025-10-22 | Syngenta Crop Protection AG | Improved pesticidal compositions |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1030756A (en) * | 1963-04-01 | 1966-05-25 | Boots Pure Drug Co Ltd | Anti-inflammatory compositions comprising biphenylyl-alkane derivatives |
| US3393192A (en) * | 1965-04-26 | 1968-07-16 | Schering Corp | Novel benzazepines |
| DK133742B (da) | 1970-10-30 | 1976-07-12 | Merck & Co Inc | Fremgangsmåde til fremstilling af 2-acetamidoethyl-(3-trifluormethylphenoxy)-(4-chlorphenyl)-acetat. |
| FR2131802A7 (en) * | 1971-03-11 | 1972-11-17 | Micsunescu Francine | Galvanizing bath brigenting agents - produced by reacting aromatic aldehydes or ketones with acetylenic alcohols |
| FR2120246A5 (es) * | 1970-12-03 | 1972-08-18 | Micsunescu Francine | |
| FR2259160A1 (en) * | 1974-01-29 | 1975-08-22 | Popescu Francine | Electrolytic bath contg acetal or ketal brightners - for use in prodn of electrolytic high gloss zinc coatings |
| GT199800109A (es) * | 1997-08-06 | 2000-01-13 | Derivados de n-sulfonilglicinalquiniloxifenetilamida microbicidas. | |
| GB9804265D0 (en) * | 1998-02-27 | 1998-04-22 | Ciba Geigy Ag | Organic compounds |
| TW564244B (en) * | 1999-01-11 | 2003-12-01 | Novartis Ag | Novel propargylether derivatives |
| GB0011944D0 (en) * | 2000-05-17 | 2000-07-05 | Novartis Ag | Organic compounds |
| GB0108339D0 (en) * | 2001-04-03 | 2001-05-23 | Syngenta Participations Ag | Organics compounds |
| GB0127559D0 (en) * | 2001-11-16 | 2002-01-09 | Syngenta Participations Ag | Organic compounds |
| GB0127554D0 (en) * | 2001-11-16 | 2002-01-09 | Syngenta Participations Ag | Organic compounds |
| EP1541557A1 (en) * | 2002-08-19 | 2005-06-15 | Sumitomo Chemical Company, Limited | Phenylpyridine compound and bactericidal composition containing the same |
| JP2006182761A (ja) * | 2004-12-02 | 2006-07-13 | Hokko Chem Ind Co Ltd | アセトニトリル化合物および農園芸用殺菌剤 |
-
2005
- 2005-08-15 GB GBGB0516705.1A patent/GB0516705D0/en not_active Ceased
-
2006
- 2006-08-01 TW TW102113033A patent/TWI428314B/zh active
- 2006-08-01 TW TW095128089A patent/TWI399363B/zh active
- 2006-08-08 KR KR1020087003753A patent/KR101305928B1/ko active Active
- 2006-08-08 AU AU2006281293A patent/AU2006281293B2/en active Active
- 2006-08-08 ES ES06765248T patent/ES2572137T3/es active Active
- 2006-08-08 MX MX2008001794A patent/MX2008001794A/es active IP Right Grant
- 2006-08-08 RU RU2008110063/04A patent/RU2470914C9/ru active
- 2006-08-08 WO PCT/GB2006/002946 patent/WO2007020381A2/en not_active Ceased
- 2006-08-08 EP EP06765248.7A patent/EP1919857B1/en active Active
- 2006-08-08 HU HUE06765248A patent/HUE028929T2/en unknown
- 2006-08-08 CN CN2006800297859A patent/CN101243040B/zh active Active
- 2006-08-08 UA UAA200814871A patent/UA90810C2/ru unknown
- 2006-08-08 CA CA2619435A patent/CA2619435C/en active Active
- 2006-08-08 US US12/063,907 patent/US8129560B2/en active Active
- 2006-08-08 NZ NZ574781A patent/NZ574781A/en active Application Filing
- 2006-08-08 BR BRPI0616593-1A patent/BRPI0616593B1/pt active IP Right Grant
- 2006-08-08 PL PL06765248.7T patent/PL1919857T3/pl unknown
- 2006-08-08 JP JP2008526532A patent/JP5350790B2/ja active Active
- 2006-08-09 AR ARP060103483A patent/AR057741A1/es active IP Right Grant
- 2006-08-11 MY MYPI20063914 patent/MY150654A/en unknown
- 2006-08-11 GT GT200600369A patent/GT200600369A/es unknown
- 2006-08-15 HN HN2006029142A patent/HN2006029142A/es unknown
-
2008
- 2008-01-21 IL IL188919A patent/IL188919A/en active IP Right Grant
- 2008-01-23 ZA ZA2008/00691A patent/ZA200800691B/en unknown
- 2008-02-01 CR CR9710A patent/CR9710A/es unknown
- 2008-02-13 EC EC2008008183A patent/ECSP088183A/es unknown
-
2010
- 2010-07-15 AR ARP100102586A patent/AR080271A2/es active IP Right Grant
-
2013
- 2013-05-16 IL IL226404A patent/IL226404A0/en unknown
- 2013-05-16 IL IL226403A patent/IL226403A0/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |