[go: up one dir, main page]

MX2007009108A - Imidazole derivatives. - Google Patents

Imidazole derivatives.

Info

Publication number
MX2007009108A
MX2007009108A MX2007009108A MX2007009108A MX2007009108A MX 2007009108 A MX2007009108 A MX 2007009108A MX 2007009108 A MX2007009108 A MX 2007009108A MX 2007009108 A MX2007009108 A MX 2007009108A MX 2007009108 A MX2007009108 A MX 2007009108A
Authority
MX
Mexico
Prior art keywords
sup
imidazole derivatives
compounds
mglur
treating
Prior art date
Application number
MX2007009108A
Other languages
Spanish (es)
Inventor
Erwin Goetschi
Juergen Wichmann
Silvia Gatti Mcarthur
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2007009108A publication Critical patent/MX2007009108A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention relates to compounds of formula I: wherein R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup> and X are as defined in the specification, methods of preparation thereof and uses thereof, which compounds are useful for preventing and treating mGluR 2 receptor mediated disorders.
MX2007009108A 2005-02-03 2006-01-30 Imidazole derivatives. MX2007009108A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05100751 2005-02-03
PCT/EP2006/000762 WO2006082002A1 (en) 2005-02-03 2006-01-30 Imidazole derivatives

Publications (1)

Publication Number Publication Date
MX2007009108A true MX2007009108A (en) 2007-09-06

Family

ID=36180610

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007009108A MX2007009108A (en) 2005-02-03 2006-01-30 Imidazole derivatives.

Country Status (11)

Country Link
US (1) US20060173048A1 (en)
EP (1) EP1846389A1 (en)
JP (1) JP2008528649A (en)
KR (1) KR20070107093A (en)
CN (1) CN101155796A (en)
AU (1) AU2006210048A1 (en)
BR (1) BRPI0606783A2 (en)
CA (1) CA2596854A1 (en)
IL (1) IL184559A0 (en)
MX (1) MX2007009108A (en)
WO (1) WO2006082002A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8012986B2 (en) 2007-04-02 2011-09-06 Hoffmann-La Roche Inc. Pyridine and pyrimidine derivatives as MGLUR2 antagonists
WO2009097414A1 (en) * 2008-01-29 2009-08-06 Vanda Pharmaceuticals, Inc. Use of imidazolylalkyl-pyridines for the treatment of addictive disorders
WO2012084678A1 (en) 2010-12-23 2012-06-28 Syngenta Participations Ag Novel imidazoles useful as plant fungicides
KR102447094B1 (en) * 2014-08-13 2022-09-23 닛뽕소다 가부시키가이샤 Diarylimidazole compounds and pest control agents
US11976045B1 (en) 2023-10-23 2024-05-07 King Faisal University 3-(4,5-bis(4-bromophenyl)-2-(4-chlorophenyl)-1H-imidazol-1-yl)propanoic acid as an antimicrobial compound
US11912665B1 (en) 2023-10-25 2024-02-27 King Faisal University 4-(2,4,5-tris(4-chlorophenyl)-1H-imidazol-1-yl)butanoic acid as an antimicrobial compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000507545A (en) * 1996-03-25 2000-06-20 スミスクライン・ビーチャム・コーポレイション Novel treatment for CNS injury
ES2289004T3 (en) * 2000-11-20 2008-02-01 Smithkline Beecham Corporation NEW COMPOUNDS.
US7091222B2 (en) * 2003-07-03 2006-08-15 Hoffmann-La Roche Inc. Imidazole derivatives

Also Published As

Publication number Publication date
IL184559A0 (en) 2007-10-31
CN101155796A (en) 2008-04-02
US20060173048A1 (en) 2006-08-03
KR20070107093A (en) 2007-11-06
EP1846389A1 (en) 2007-10-24
JP2008528649A (en) 2008-07-31
WO2006082002A1 (en) 2006-08-10
AU2006210048A1 (en) 2006-08-10
CA2596854A1 (en) 2006-08-10
BRPI0606783A2 (en) 2009-07-14

Similar Documents

Publication Publication Date Title
MX2010007392A (en) Trpa1 antagonists.
WO2009046841A8 (en) Piperidine and piperazine derivatives for treating tumours
WO2007140439A3 (en) Compounds as cannabinoid receptor ligands and uses thereof
MX2010007391A (en) Trpa1 antagonists.
WO2009117676A3 (en) Novel piperidine derivatives as inhibitors of stearoyl-coa desaturase
WO2010033543A3 (en) Substituted benzamides as cannabinoid receptor ligands
TW200942535A (en) Novel compounds as cannabinoid receptor ligands
WO2010071783A8 (en) Thiazoles as cannabinoid receptor ligands
WO2010063700A8 (en) Novel pyrazole-4 -n-alkoxycarboxamides as microbiocides
MX2010003368A (en) Imidazole derivatives.
WO2008130953A3 (en) 2-imin0is0thiaz0le derivatives as cannabinoid receptor ligands
MX2009009590A (en) Aminopyrimidines useful as inhibitors of protein kinases.
WO2008027812A3 (en) Imidazopyridine and imidazopyrimidine derivatives
WO2005123703A3 (en) Alkynyl derivatives as modulators of metabotropic glutamate receptors
WO2009024342A3 (en) Novel microbiocides
WO2010033701A3 (en) Inhibitors of sphingosine kinase 1
WO2010028338A3 (en) Novel compounds as cannabinoid receptor ligands
WO2010054024A3 (en) 1, 2 -thiazol yl derivatives as cannabinoid receptor ligands
WO2010062927A3 (en) Substituted octahydrocyclopnta (c) pyrrol-4 -amines as calcium channel blockers
MX2009007713A (en) Pyridazine derivatives, processes for their preparation and their use as fungicides.
MX2010003365A (en) Thiazol derivatives for treating cancer.
MY147649A (en) Benzimidazole derivatives useful in treatment of vallinoid receptor trpv1 related disorders
GB0510143D0 (en) Novel compounds A1
TNSN08370A1 (en) Tetrahydropyridothienopyrimidine compounds and methods of use thereof
IL191751A0 (en) Pyrrolo[2,3-c]pyridine derivatives

Legal Events

Date Code Title Description
FA Abandonment or withdrawal