MX2007004749A - Uso de agosnitas de receptor a2a de adenosina. - Google Patents
Uso de agosnitas de receptor a2a de adenosina.Info
- Publication number
- MX2007004749A MX2007004749A MX2007004749A MX2007004749A MX2007004749A MX 2007004749 A MX2007004749 A MX 2007004749A MX 2007004749 A MX2007004749 A MX 2007004749A MX 2007004749 A MX2007004749 A MX 2007004749A MX 2007004749 A MX2007004749 A MX 2007004749A
- Authority
- MX
- Mexico
- Prior art keywords
- receptor agonists
- adenosine receptor
- myocardial imaging
- adenosine
- accomplished
- Prior art date
Links
- 101150051188 Adora2a gene Proteins 0.000 title 1
- 239000003379 purinergic P1 receptor agonist Substances 0.000 title 1
- 238000003384 imaging method Methods 0.000 abstract 2
- 230000002107 myocardial effect Effects 0.000 abstract 2
- 229940122086 Adenosine A2a receptor agonist Drugs 0.000 abstract 1
- 239000002465 adenosine A2a receptor agonist Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960003614 regadenoson Drugs 0.000 abstract 1
- LZPZPHGJDAGEJZ-AKAIJSEGSA-N regadenoson Chemical compound C1=C(C(=O)NC)C=NN1C1=NC(N)=C(N=CN2[C@H]3[C@@H]([C@H](O)[C@@H](CO)O3)O)C2=N1 LZPZPHGJDAGEJZ-AKAIJSEGSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Radiology & Medical Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Abstract
Metodos de formacion de imagen miocardica que se realizan administrando dosis de una composicion farmaceutica que incluye regadenoson - un agonista de receptor A2A de adenosina - a un humano que experimenta formacion de imagen miocardica en una cantidad suficiente para alcanzar por lo menos un incremento minimo en la velocidad pico de flujo coronario promedio.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62057704P | 2004-10-20 | 2004-10-20 | |
| PCT/US2005/037368 WO2006044856A2 (en) | 2004-10-20 | 2005-10-19 | Use of a2a adenosine receptor agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007004749A true MX2007004749A (es) | 2007-06-18 |
Family
ID=35953984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007004749A MX2007004749A (es) | 2004-10-20 | 2005-10-19 | Uso de agosnitas de receptor a2a de adenosina. |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US7655636B2 (es) |
| EP (1) | EP1802317A2 (es) |
| JP (1) | JP2008517063A (es) |
| KR (1) | KR20070083714A (es) |
| CN (1) | CN101076343A (es) |
| AU (1) | AU2005295437B2 (es) |
| CA (1) | CA2583185A1 (es) |
| IL (1) | IL182645A0 (es) |
| MX (1) | MX2007004749A (es) |
| NO (1) | NO20072540L (es) |
| RU (1) | RU2007114908A (es) |
| WO (1) | WO2006044856A2 (es) |
| ZA (1) | ZA200703229B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6403567B1 (en) * | 1999-06-22 | 2002-06-11 | Cv Therapeutics, Inc. | N-pyrazole A2A adenosine receptor agonists |
| US6214807B1 (en) * | 1999-06-22 | 2001-04-10 | Cv Therapeutics, Inc. | C-pyrazole 2A A receptor agonists |
| USRE47351E1 (en) | 1999-06-22 | 2019-04-16 | Gilead Sciences, Inc. | 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists |
| WO2001062979A2 (en) * | 2000-02-23 | 2001-08-30 | Cv Therapeutics, Inc. | Dentification of partial agonists of the a2a adenosine receptor |
| US8470801B2 (en) * | 2002-07-29 | 2013-06-25 | Gilead Sciences, Inc. | Myocardial perfusion imaging methods and compositions |
| US20050020915A1 (en) * | 2002-07-29 | 2005-01-27 | Cv Therapeutics, Inc. | Myocardial perfusion imaging methods and compositions |
| JP2005538190A (ja) * | 2002-07-29 | 2005-12-15 | シーブイ・セラピューティクス・インコーポレイテッド | 心筋潅流イメージング |
| RU2007114908A (ru) | 2004-10-20 | 2008-10-27 | Си Ви ТЕРАПЬЮСи Ви ТЕРАПЬЮТИКСИКС | Применение агонистов аденозиновых рецепторов a2a |
| CA2640089C (en) | 2006-02-03 | 2013-07-23 | Cv Therapeutics, Inc. | Process for preparing an a2a-adenosine receptor agonist and its polymorphs |
| EP2068850A1 (en) * | 2006-06-22 | 2009-06-17 | Cv Therapeutics, Inc. | Use of a2a adenosine receptor agonists in the treatment of ischemia |
| US20090081120A1 (en) * | 2006-09-01 | 2009-03-26 | Cv Therapeutics, Inc. | Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods |
| JP2010502649A (ja) * | 2006-09-01 | 2010-01-28 | シーブイ・セラピューティクス・インコーポレイテッド | 心筋層画像化法中の患者の耐性を増加させるための方法および組成物 |
| EP2066232A1 (en) * | 2006-09-29 | 2009-06-10 | Cv Therapeutics, Inc. | Methods for myocardial imaging in patients having a history of pulmonary disease |
| US20080267861A1 (en) * | 2007-01-03 | 2008-10-30 | Cv Therapeutics, Inc. | Myocardial Perfusion Imaging |
| RU2011115815A (ru) * | 2008-09-29 | 2012-11-10 | Гайлид Сайэнсиз, Инк. (Us) | Комбинации средства, регулирующего частоту сердечных сокращений и агониста а-2-альфа рецепторов для применения в способах мультидетекторной компьютерной томографии |
| US20150290236A1 (en) * | 2012-11-30 | 2015-10-15 | Leiutis Pharmaceuticals Pvt. Ltd. | Pharmaceutical compositions of regadenoson |
| US11445912B2 (en) | 2015-09-30 | 2022-09-20 | Cedars-Sinai Medical Center | Robust myocardial blood oxygen level dependent magnetic resonance imaging with long acting coronary vasodilators |
| JP7431173B2 (ja) | 2018-04-26 | 2024-02-14 | シーダーズ-サイナイ メディカル センター | 高度時間分解心筋血中酸素レベル依存性磁気共鳴画像化の方法 |
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| DK135130B (da) | 1970-12-28 | 1977-03-07 | Takeda Chemical Industries Ltd | Analogifremgangsmåde til fremstilling af 2-substituerede adenosinderivater eller syreadditionssalte deraf. |
| BE787064A (fr) | 1971-08-03 | 1973-02-01 | Philips Nv | Dispositif magnetique comportant des domaines |
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| JP2005538190A (ja) * | 2002-07-29 | 2005-12-15 | シーブイ・セラピューティクス・インコーポレイテッド | 心筋潅流イメージング |
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| EP2068850A1 (en) * | 2006-06-22 | 2009-06-17 | Cv Therapeutics, Inc. | Use of a2a adenosine receptor agonists in the treatment of ischemia |
| US20090081120A1 (en) | 2006-09-01 | 2009-03-26 | Cv Therapeutics, Inc. | Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods |
| JP2010502649A (ja) * | 2006-09-01 | 2010-01-28 | シーブイ・セラピューティクス・インコーポレイテッド | 心筋層画像化法中の患者の耐性を増加させるための方法および組成物 |
| EP2066232A1 (en) * | 2006-09-29 | 2009-06-10 | Cv Therapeutics, Inc. | Methods for myocardial imaging in patients having a history of pulmonary disease |
| US20080267861A1 (en) * | 2007-01-03 | 2008-10-30 | Cv Therapeutics, Inc. | Myocardial Perfusion Imaging |
| RU2011115815A (ru) * | 2008-09-29 | 2012-11-10 | Гайлид Сайэнсиз, Инк. (Us) | Комбинации средства, регулирующего частоту сердечных сокращений и агониста а-2-альфа рецепторов для применения в способах мультидетекторной компьютерной томографии |
-
2005
- 2005-10-19 RU RU2007114908/142007114908/14A patent/RU2007114908A/ru not_active Application Discontinuation
- 2005-10-19 MX MX2007004749A patent/MX2007004749A/es not_active Application Discontinuation
- 2005-10-19 AU AU2005295437A patent/AU2005295437B2/en not_active Ceased
- 2005-10-19 KR KR1020077008782A patent/KR20070083714A/ko not_active Ceased
- 2005-10-19 WO PCT/US2005/037368 patent/WO2006044856A2/en not_active Ceased
- 2005-10-19 CN CNA2005800356405A patent/CN101076343A/zh active Pending
- 2005-10-19 CA CA002583185A patent/CA2583185A1/en not_active Abandoned
- 2005-10-19 EP EP05815368A patent/EP1802317A2/en not_active Withdrawn
- 2005-10-19 JP JP2007537961A patent/JP2008517063A/ja not_active Withdrawn
- 2005-10-19 US US11/253,322 patent/US7655636B2/en not_active Expired - Fee Related
-
2007
- 2007-04-18 IL IL182645A patent/IL182645A0/en unknown
- 2007-04-19 ZA ZA200703229A patent/ZA200703229B/xx unknown
- 2007-05-18 NO NO20072540A patent/NO20072540L/no not_active Application Discontinuation
-
2009
- 2009-12-14 US US12/637,583 patent/US8106029B2/en not_active Expired - Lifetime
-
2011
- 2011-12-21 US US13/333,789 patent/US20120189538A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL182645A0 (en) | 2007-07-24 |
| CN101076343A (zh) | 2007-11-21 |
| US7655636B2 (en) | 2010-02-02 |
| RU2007114908A (ru) | 2008-10-27 |
| CA2583185A1 (en) | 2006-04-27 |
| JP2008517063A (ja) | 2008-05-22 |
| US20120189538A1 (en) | 2012-07-26 |
| WO2006044856A3 (en) | 2006-07-06 |
| NO20072540L (no) | 2007-05-18 |
| ZA200703229B (en) | 2009-07-29 |
| AU2005295437B2 (en) | 2011-05-19 |
| US8106029B2 (en) | 2012-01-31 |
| US20100158797A1 (en) | 2010-06-24 |
| EP1802317A2 (en) | 2007-07-04 |
| AU2005295437A1 (en) | 2006-04-27 |
| WO2006044856A2 (en) | 2006-04-27 |
| KR20070083714A (ko) | 2007-08-24 |
| US20060084625A1 (en) | 2006-04-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or rights |
Owner name: GILEAD SCIENCES, INC. |
|
| HC | Change of company name or juridical status |
Owner name: GILEAD SCIENCES, INC. |
|
| GB | Transfer or rights |
Owner name: GILEAD SCIENCES, INC. |
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| FA | Abandonment or withdrawal |