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MX2007001597A - Granulos que comprenden paracetamol, un farmaco antiinflamatorio no esteroidal y un alcohol de azucar hecho por extrusion por fusion. - Google Patents

Granulos que comprenden paracetamol, un farmaco antiinflamatorio no esteroidal y un alcohol de azucar hecho por extrusion por fusion.

Info

Publication number
MX2007001597A
MX2007001597A MX2007001597A MX2007001597A MX2007001597A MX 2007001597 A MX2007001597 A MX 2007001597A MX 2007001597 A MX2007001597 A MX 2007001597A MX 2007001597 A MX2007001597 A MX 2007001597A MX 2007001597 A MX2007001597 A MX 2007001597A
Authority
MX
Mexico
Prior art keywords
nsaid
paracetamol
sugar alcohol
granules
melt extrusion
Prior art date
Application number
MX2007001597A
Other languages
English (en)
Inventor
Robert Sherry
Original Assignee
Reckitt Benckiser Healthcare
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0417942A external-priority patent/GB0417942D0/en
Priority claimed from GB0417939A external-priority patent/GB0417939D0/en
Application filed by Reckitt Benckiser Healthcare filed Critical Reckitt Benckiser Healthcare
Publication of MX2007001597A publication Critical patent/MX2007001597A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describe una composicion farmaceutica que comprende un componente granular que comprende una pluralidad de granulos fundidos solidificados de un alcohol de azucar que tiene una sal de un farmaco anti-inflamatorio no esteroidal (sal de NSAID) y paracetamol contenido en este.
MX2007001597A 2004-08-12 2005-08-08 Granulos que comprenden paracetamol, un farmaco antiinflamatorio no esteroidal y un alcohol de azucar hecho por extrusion por fusion. MX2007001597A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0417942A GB0417942D0 (en) 2004-08-12 2004-08-12 Therapeutic agents
GB0417939A GB0417939D0 (en) 2004-08-12 2004-08-12 Therapeutic agents
PCT/GB2005/003079 WO2006016126A1 (en) 2004-08-12 2005-08-08 Granules comprising paracetamol a nsaid and a sugar alcohol made by melt extrusion

Publications (1)

Publication Number Publication Date
MX2007001597A true MX2007001597A (es) 2007-05-23

Family

ID=35044771

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2007001597A MX2007001597A (es) 2004-08-12 2005-08-08 Granulos que comprenden paracetamol, un farmaco antiinflamatorio no esteroidal y un alcohol de azucar hecho por extrusion por fusion.
MX2007001689A MX2007001689A (es) 2004-08-12 2005-08-08 Granulos que comprenden un farmaco antiinflamatorio no esteroidal y un alcohol de azucar hecho por extrusion en fase fundida.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2007001689A MX2007001689A (es) 2004-08-12 2005-08-08 Granulos que comprenden un farmaco antiinflamatorio no esteroidal y un alcohol de azucar hecho por extrusion en fase fundida.

Country Status (14)

Country Link
US (2) US20070254028A1 (es)
EP (2) EP1804772B1 (es)
JP (2) JP2008509207A (es)
KR (3) KR20070069143A (es)
CN (2) CN102631325A (es)
AR (2) AR050783A1 (es)
AT (1) ATE526949T1 (es)
AU (3) AU2005271035B2 (es)
CA (2) CA2576642A1 (es)
MX (2) MX2007001597A (es)
PL (2) PL1799195T3 (es)
PT (1) PT1804772E (es)
RU (2) RU2389478C2 (es)
WO (2) WO2006016126A1 (es)

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GB0519350D0 (en) * 2005-09-22 2005-11-02 Boots Healthcare Int Ltd Therapeutic agents
EP1808163A1 (en) * 2005-12-22 2007-07-18 Teva Pharmaceutical Industries Ltd. Compressed solid dosage forms with drugs of low solubility and process for making the same
CN101340896A (zh) * 2005-12-22 2009-01-07 特瓦制药工业有限公司 含有低溶解性药物的压缩的固体剂型和其制备方法
US8083603B2 (en) * 2007-11-09 2011-12-27 Qubicaamf Worldwide Llc Bowling bumper system and method of use and installation
WO2009128543A1 (ja) * 2008-04-17 2009-10-22 ニプロ株式会社 シリカを含む錠剤の製造方法、錠剤及び錠剤用複合粒子
US8759279B2 (en) * 2008-06-30 2014-06-24 Kimberly-Clark Worldwide, Inc. Fragranced biodegradable film
WO2011001228A1 (en) * 2008-08-14 2011-01-06 Shasun Chemicals And Drugs Limited Aryl alkyl carboxylic acid salts, process for preparation and dosage forms
EP2238974B9 (en) * 2009-04-09 2014-05-21 E-Pharma Trento S.p.A. Granulate for the formulation of orodispersible tablets
RU2011150661A (ru) * 2009-06-22 2013-07-27 ВАЙЕТ ЭлЭлСи Таблетки ибупрофена натрия и способы изготовления фармацевтических композиций, включающих ибупрофен натрия
EA019805B1 (ru) * 2010-09-16 2014-06-30 Закрытое Акционерное Общество "Афофарм" Комбинированный анальгетик на основе парацетамола
JP5750856B2 (ja) * 2010-10-04 2015-07-22 ライオン株式会社 固形医薬組成物及び医薬製剤
RU2449777C1 (ru) * 2010-12-20 2012-05-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Новосибирский национальный исследовательский государственный университет" (Новосибирский государственный университет, НГУ) Способ получения высокодисперсного парацетамола
JP6255908B2 (ja) * 2012-11-09 2018-01-10 大正製薬株式会社 固形製剤
FR2997856B1 (fr) * 2012-11-14 2015-04-24 Pf Medicament Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
RU2015132902A (ru) 2013-01-07 2017-02-09 Сам-А Фарм. Ко., Лтд. Новый быстрорастворимый состав гранул с улучшенной растворимостью
CN104723597B (zh) * 2015-03-23 2017-04-05 辽宁天亿机械有限公司 一种间歇式压片机
UA126916C2 (uk) * 2017-04-27 2023-02-22 Др. Редді'З Лабораторіз Лімітед Фармацевтична композиція кеторолаку
WO2023281089A2 (en) 2021-07-08 2023-01-12 Krka, D.D., Novo Mesto Pharmaceutical composition comprising naproxen and paracetamol
CN114041519A (zh) * 2021-11-25 2022-02-15 浙江华康药业股份有限公司 一种制备可直接压片木糖醇颗粒的方法
AU2022201576A1 (en) * 2022-03-08 2023-09-28 Aft Pharmaceuticals Limited Medication
WO2024097694A1 (en) * 2022-11-04 2024-05-10 Johnson & Johnson Consumer Inc. Acetaminophen and naproxen for treating pain

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* Cited by examiner, † Cited by third party
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CH677606A5 (es) * 1988-07-12 1991-06-14 Aesculapius Pharma Sa
US5075291A (en) * 1989-11-22 1991-12-24 Ici Americas Inc. Crystalline sugar alcohol containing uniformly dispersed particulate pharmaceutical compound
SK279279B6 (sk) * 1991-05-13 1998-09-09 The Boots Company Plc S(-)-nátrium-2-(4-izobutylfenyl)propionát-dihydrát
DK0566709T5 (da) * 1991-09-06 2009-05-18 Ortho Mcneil Janssen Pharm Præparat indeholdende et tramadolmateriale og acetaminophen og anvendelse deraf
US5409709A (en) * 1991-11-29 1995-04-25 Lion Corporation Antipyretic analgesic preparation containing ibuprofen
FR2705677B1 (fr) * 1993-05-28 1995-08-11 Roquette Freres Micro-granules obtenus par extrusion-sphéronisation contenant une cyclodextrine.
DE19504832A1 (de) * 1995-02-14 1996-08-22 Basf Ag Feste Wirkstoff-Zubereitungen
GB9603699D0 (en) * 1996-02-21 1996-04-17 Boots Co Plc Therapeutic composition
GB9616536D0 (en) * 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
US6649186B1 (en) * 1996-09-20 2003-11-18 Ethypharm Effervescent granules and methods for their preparation
US6160020A (en) * 1996-12-20 2000-12-12 Mcneill-Ppc, Inc. Alkali metal and alkaline-earth metal salts of acetaminophen
DE19710213A1 (de) * 1997-03-12 1998-09-17 Basf Ag Verfahren zur Herstellung von festen Kombinationsarzneiformen
DE19809242A1 (de) * 1998-03-05 1999-09-09 Basf Ag Verfahren zur Herstellung von festen, sphärischen Formkörpern, enthaltend pharmazeutische Wirkstoffe in einer Bindemittelmatrix
CA2417736A1 (en) * 2000-07-19 2002-01-24 Lavipharm Laboratories, Inc. Sildenafil citrate solid dispersions having high water solubility
FR2814366A1 (fr) * 2000-09-22 2002-03-29 Rhodia Chimie Sa Procede de granulation de matieres actives par extrusion basse pression pour l'obtention de granules directement compressibles
AU2002258013A1 (en) * 2001-04-10 2002-10-28 Fakhreddin Jamali Animal model for evaluating analgesics
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
GB0113842D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
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Also Published As

Publication number Publication date
AU2010200633A1 (en) 2010-03-11
CN102784113A (zh) 2012-11-21
CN102631325A (zh) 2012-08-15
HK1104965A1 (en) 2008-02-01
US20080085308A1 (en) 2008-04-10
EP1804772B1 (en) 2011-10-05
AR050783A1 (es) 2006-11-22
JP2008509207A (ja) 2008-03-27
US20070254028A1 (en) 2007-11-01
RU2007108779A (ru) 2008-09-20
AU2005271035A1 (en) 2006-02-16
PL1799195T3 (pl) 2016-09-30
EP1799195B1 (en) 2016-03-23
CA2576642A1 (en) 2006-02-16
KR101232114B1 (ko) 2013-02-13
PL1804772T3 (pl) 2012-03-30
RU2389478C2 (ru) 2010-05-20
EP1804772A1 (en) 2007-07-11
AU2005271036B2 (en) 2009-11-19
CA2576652A1 (en) 2006-02-16
RU2389480C2 (ru) 2010-05-20
AU2005271036A1 (en) 2006-02-16
AR052523A1 (es) 2007-03-21
WO2006016125A1 (en) 2006-02-16
AU2010200633B2 (en) 2013-01-31
EP1799195A1 (en) 2007-06-27
KR101482922B1 (ko) 2015-01-15
KR20070062978A (ko) 2007-06-18
KR20130014647A (ko) 2013-02-07
JP2008509206A (ja) 2008-03-27
MX2007001689A (es) 2007-06-11
KR20070069143A (ko) 2007-07-02
PT1804772E (pt) 2011-12-02
ATE526949T1 (de) 2011-10-15
WO2006016126A1 (en) 2006-02-16
RU2007108778A (ru) 2008-09-20
AU2005271035B2 (en) 2009-09-17

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