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MX2007000725A - Proceso mejorado para la fabricacion de mirtazapina. - Google Patents

Proceso mejorado para la fabricacion de mirtazapina.

Info

Publication number
MX2007000725A
MX2007000725A MX2007000725A MX2007000725A MX2007000725A MX 2007000725 A MX2007000725 A MX 2007000725A MX 2007000725 A MX2007000725 A MX 2007000725A MX 2007000725 A MX2007000725 A MX 2007000725A MX 2007000725 A MX2007000725 A MX 2007000725A
Authority
MX
Mexico
Prior art keywords
mirtazapine
improved process
manufacture
crystallineand
forpreparing
Prior art date
Application number
MX2007000725A
Other languages
English (en)
Inventor
Aguilar Carmen Arnalot
Original Assignee
Medichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem Sa filed Critical Medichem Sa
Publication of MX2007000725A publication Critical patent/MX2007000725A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Proceso mejorado para la fabricacion de mirtazapina. Se describe un procedimiento de preparacion de mirtazapina a partir de un compuesto de formula II, que se somete a una ciclacion de anillo, obteniendose mirtazapina de uso farmaceutico en forma cristalina y anhidra.
MX2007000725A 2004-07-22 2005-07-19 Proceso mejorado para la fabricacion de mirtazapina. MX2007000725A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200401804A ES2246161B1 (es) 2004-07-22 2004-07-22 Proceso mejorado para la fabricacion de mirtazapina.
PCT/EP2005/053493 WO2006008302A2 (en) 2004-07-22 2005-07-19 Improved process for the manufacture of mirtazapine

Publications (1)

Publication Number Publication Date
MX2007000725A true MX2007000725A (es) 2007-05-23

Family

ID=35509331

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007000725A MX2007000725A (es) 2004-07-22 2005-07-19 Proceso mejorado para la fabricacion de mirtazapina.

Country Status (17)

Country Link
US (1) US20080207896A1 (es)
EP (1) EP1768980B1 (es)
KR (1) KR20070053697A (es)
AR (1) AR050004A1 (es)
AT (1) ATE415401T1 (es)
AU (1) AU2005263761A1 (es)
BR (1) BRPI0513571A (es)
CA (1) CA2572831A1 (es)
DE (1) DE602005011294D1 (es)
DK (1) DK1768980T3 (es)
ES (2) ES2246161B1 (es)
IL (1) IL180345A0 (es)
MX (1) MX2007000725A (es)
NO (1) NO20070776L (es)
PT (1) PT1768980E (es)
RU (1) RU2007106721A (es)
WO (1) WO2006008302A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101485418B1 (ko) * 2013-05-29 2015-01-26 주식회사 메디켐코리아 고순도 미르타자핀의 제조방법
PT3261645T (pt) 2015-02-27 2021-06-17 Dechra Ltd Estimulação do apetite, gestão da perda de peso, e tratamento da anorexia em cães e gatos
JP6452575B2 (ja) * 2015-08-19 2019-01-16 株式会社トクヤマ ミルタザピンの製造方法
KR102540021B1 (ko) * 2020-12-02 2023-06-07 (주)유케이케미팜 대량 생산에 적합한 미르타자핀의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2547319B1 (fr) * 1983-06-09 1987-10-09 Gleizes Raymond Procede et appareil de fabrication de couches monocristallines et macrocristallines, notamment pour cellules photovoltaiques
US6012983A (en) * 1996-12-30 2000-01-11 Walker Asset Management Limited Partnership Automated play gaming device
US6960133B1 (en) * 2000-08-28 2005-11-01 Igt Slot machine game having a plurality of ways for a user to obtain payouts based on selection of one or more symbols (power pays)
US6545149B2 (en) * 1999-04-19 2003-04-08 Teva Pharmaceutical Industries Ltd. Synthesis and crystallization of piperazine ring-containing compounds
EP1178805A4 (en) * 1999-04-19 2004-11-24 Teva Pharma NOVEL SYNTHESIS AND CRYSTALLIZATION OF PIPERAZINE-CONTAINING COMPOUNDS
TR200103028T2 (tr) * 1999-04-19 2002-01-21 Teva Pharmaceutical Industries Ltd. Piperazin halka içeren bileşiklerin yeni sentezi ve kristalleştirilmesi

Also Published As

Publication number Publication date
EP1768980B1 (en) 2008-11-26
PT1768980E (pt) 2009-03-02
DK1768980T3 (da) 2009-03-16
IL180345A0 (en) 2007-06-03
AR050004A1 (es) 2006-09-20
NO20070776L (no) 2007-04-11
WO2006008302A3 (en) 2006-04-13
ATE415401T1 (de) 2008-12-15
BRPI0513571A (pt) 2008-05-06
DE602005011294D1 (de) 2009-01-08
EP1768980A2 (en) 2007-04-04
RU2007106721A (ru) 2008-08-27
US20080207896A1 (en) 2008-08-28
ES2246161A1 (es) 2006-02-01
WO2006008302A2 (en) 2006-01-26
CA2572831A1 (en) 2006-01-26
KR20070053697A (ko) 2007-05-25
ES2318520T3 (es) 2009-05-01
ES2246161B1 (es) 2007-04-01
AU2005263761A1 (en) 2006-01-26

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