MX2007000406A - Solucion para infusion e inyeccion de levodopa. - Google Patents
Solucion para infusion e inyeccion de levodopa.Info
- Publication number
- MX2007000406A MX2007000406A MX2007000406A MX2007000406A MX2007000406A MX 2007000406 A MX2007000406 A MX 2007000406A MX 2007000406 A MX2007000406 A MX 2007000406A MX 2007000406 A MX2007000406 A MX 2007000406A MX 2007000406 A MX2007000406 A MX 2007000406A
- Authority
- MX
- Mexico
- Prior art keywords
- levodopa
- infusion
- injection solution
- metabolising enzyme
- optionally
- Prior art date
Links
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 title abstract 6
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 title abstract 6
- 229960004502 levodopa Drugs 0.000 title abstract 6
- 238000001802 infusion Methods 0.000 title abstract 5
- 239000000243 solution Substances 0.000 title abstract 5
- 238000002347 injection Methods 0.000 title abstract 4
- 239000007924 injection Substances 0.000 title abstract 4
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se describe una solucion para infusion o inyeccion de Levodopa que contiene al menos 10 mg/mL de Levodopa, o al menos 5 mg/mL de Levodopa junto con al menos 0.5 mg/mL de al menos un inhibidor de enzima metabolizadora de Levodopa. La solucion contiene ademas un regulador, un azucar aceptable fisiologicamente, tal como glucosa, un acido aceptble fisiologicamente, tal como acido clorhidrico, y opcionalmente un estabilizador, y tiene un pH menor o igual que 6. Tambien se describe una jeringa desechable que contiene una solucion para infusion o inyeccion de Levodopa, opcionalmente junto con una enzima metabolizadora de Levodopa, y un casete para bomba de infusion que contiene una solucion para infusion o inyeccion de Levodopa opcionalmente junto con una enzima metabolizadora de Levodopa.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0401842A SE0401842D0 (sv) | 2004-07-12 | 2004-07-12 | Infusion and injection solution of levodopa |
| PCT/SE2005/001135 WO2006006929A1 (en) | 2004-07-12 | 2005-07-08 | Infusion and injection solution of levodopa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007000406A true MX2007000406A (es) | 2007-06-25 |
Family
ID=32867227
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007000406A MX2007000406A (es) | 2004-07-12 | 2005-07-08 | Solucion para infusion e inyeccion de levodopa. |
| MX2013006111A MX349829B (es) | 2004-07-12 | 2005-07-08 | Solucion para infusion e inyeccion de levodopa. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013006111A MX349829B (es) | 2004-07-12 | 2005-07-08 | Solucion para infusion e inyeccion de levodopa. |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US20080255235A1 (es) |
| EP (2) | EP1773297B1 (es) |
| JP (3) | JP2008505966A (es) |
| KR (1) | KR20070042172A (es) |
| CN (1) | CN101022784B (es) |
| AU (1) | AU2005262918B2 (es) |
| BR (1) | BRPI0513293A (es) |
| CA (1) | CA2574437C (es) |
| CY (1) | CY1116197T1 (es) |
| DK (1) | DK1773297T3 (es) |
| EA (1) | EA012415B1 (es) |
| ES (1) | ES2534596T3 (es) |
| HR (1) | HRP20150384T1 (es) |
| IL (1) | IL180650A (es) |
| MX (2) | MX2007000406A (es) |
| PL (1) | PL1773297T3 (es) |
| PT (1) | PT1773297E (es) |
| SE (1) | SE0401842D0 (es) |
| SI (1) | SI1773297T1 (es) |
| WO (1) | WO2006006929A1 (es) |
| ZA (1) | ZA200700993B (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8815950B2 (en) | 2003-08-29 | 2014-08-26 | Janssen Biotech, Inc. | Pharmaceutical compositions and method of using levodopa and carbidopa |
| EP3777839A1 (en) * | 2009-05-19 | 2021-02-17 | Neuroderm Ltd | Compositions for continuous administration of dopa decarboxylase inhibitors |
| NZ610911A (en) * | 2010-11-15 | 2015-02-27 | Neuroderm Ltd | Continuous administration of l-dopa, dopa decarboxylase inhibitors, catechol-o-methyl transferase inhibitors and compositions for same |
| BR112013014304A2 (pt) * | 2010-12-10 | 2016-07-19 | Synagile Corp | composições de pró-fármaco levodopa infundíveis subcutaneamente e método de infusão |
| HRP20230276T1 (hr) * | 2012-03-20 | 2023-04-28 | Eagle Pharmaceuticals, Inc. | Tekući pripravci bendamustina za uporabu u postupku liječenja stanja koja reagiraju na bendamustin kod pacijenata kojima za primjenu trebaju reducirani volumeni |
| PT2846776T (pt) * | 2012-05-10 | 2020-05-28 | Aop Orphan Pharmaceuticals Ag | Formulação parenteral de esmolol |
| EP2854764B1 (en) | 2012-06-05 | 2018-12-12 | Neuroderm Ltd | Compositions comprising apomorphine and organic acids and uses thereof |
| KR102237007B1 (ko) * | 2012-10-22 | 2021-04-06 | 키비타스 테라퓨틱스, 인코포레이티드. | 레보도파 혈장 농도의 환자간 변산도의 감소 |
| BR112015010601B1 (pt) * | 2012-11-09 | 2022-07-19 | Civitas Therapeutics, Inc. | Composição farmacêutica e uso da composição |
| US20150182697A1 (en) * | 2013-12-31 | 2015-07-02 | Abbvie Inc. | Pump, motor and assembly for beneficial agent delivery |
| US10130755B2 (en) * | 2013-12-31 | 2018-11-20 | Abbvie Inc. | Devices and methods for delivering a beneficial agent to a user |
| EP3777833B1 (en) | 2014-03-13 | 2023-10-18 | Neuroderm Ltd. | Dopa decarboxylase inhibitor compositions |
| US10258585B2 (en) | 2014-03-13 | 2019-04-16 | Neuroderm, Ltd. | DOPA decarboxylase inhibitor compositions |
| BE1022042B1 (nl) | 2014-09-29 | 2016-02-08 | Puratos Nv | Verbeterde cakebeslagsoorten |
| KR20180004756A (ko) | 2015-05-06 | 2018-01-12 | 신애질 코포레이션 | 약물 입자를 함유하는 제약 현탁액, 그의 투여를 위한 장치, 및 그의 사용 방법 |
| MY190011A (en) * | 2016-04-11 | 2022-03-22 | Univ Canberra | Ophthalmic compositions comprising levodopa, an antioxidant and an aqueous carrier |
| IL271169B (en) * | 2017-06-05 | 2022-09-01 | Dizlin Pharmaceuticals Ab | An infusion of levodopa |
| RU2676761C1 (ru) * | 2017-10-09 | 2019-01-11 | Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" | Полиионный инфузионный раствор |
| MX2020013319A (es) | 2018-06-12 | 2021-02-22 | Novozymes As | Menos azúcar añadido en productos horneados. |
| AU2019379806B2 (en) | 2018-11-15 | 2025-08-14 | Abbvie Inc. | Pharmaceutical formulations for subcutaneous administration |
| WO2022090562A1 (en) | 2020-11-02 | 2022-05-05 | Novozymes A/S | Baked and par-baked products with thermostable amg variants from penicillium |
| US11213502B1 (en) | 2020-11-17 | 2022-01-04 | Neuroderm, Ltd. | Method for treatment of parkinson's disease |
| US11844754B2 (en) | 2020-11-17 | 2023-12-19 | Neuroderm, Ltd. | Methods for treatment of Parkinson's disease |
| US11331293B1 (en) | 2020-11-17 | 2022-05-17 | Neuroderm, Ltd. | Method for treatment of Parkinson's disease |
| US20250270485A1 (en) | 2022-05-04 | 2025-08-28 | Novozymes A/S | Brewing with thermostable amg variants |
| AU2022476759A1 (en) | 2022-09-01 | 2025-02-13 | Novozymes A/S | Baking with thermostable amg glucosidase variants (ec 3.2.1.3) and low or no added emulsifier |
| WO2024046595A1 (en) | 2022-09-01 | 2024-03-07 | Novozymes A/S | Baking with thermostable amyloglucosidase (amg) variants (ec 3.2.1.3) and low added sugar |
| JP2025536360A (ja) | 2022-10-24 | 2025-11-05 | ノボザイムス アクティーゼルスカブ | 熱安定性ＡＭＧバリアント及びα－アミラーゼを用いた焼成方法 |
| JP2025536359A (ja) | 2022-10-24 | 2025-11-05 | ノボザイムス アクティーゼルスカブ | 熱安定性アミログルコシダーゼバリアント（ｅｃ ３．２．１．３）を用いたパルスタンパク質強化パンの焼成方法 |
| CN120344150A (zh) | 2022-11-30 | 2025-07-18 | 诺维信公司 | 用热稳定葡糖淀粉酶变体在低ph下烘焙 |
| US12161612B2 (en) | 2023-04-14 | 2024-12-10 | Neuroderm, Ltd. | Methods and compositions for reducing symptoms of Parkinson's disease |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5518688B2 (es) * | 1972-12-02 | 1980-05-21 | ||
| JPS5537528B2 (es) * | 1972-12-11 | 1980-09-29 | ||
| JPS54105221A (en) * | 1978-02-02 | 1979-08-18 | Sankyo Co Ltd | Preparation of stable concentrated dopa injection |
| JPS6021570B2 (ja) * | 1978-07-04 | 1985-05-28 | 三共株式会社 | ド−パ類の高濃度製剤の製法 |
| DE252290T1 (de) * | 1986-06-10 | 1988-06-09 | Chiesi Farmaceutici S.P.A., Parma | Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen. |
| US4850980A (en) * | 1987-12-04 | 1989-07-25 | Fisher Scientific Company | I.V. pump cassette |
| CA2037178A1 (en) | 1990-02-28 | 1991-08-29 | Albert Walter Brzeczko | Deprenyl/l-dopa/carbidopa pharmaceutical composition |
| US5877176A (en) * | 1991-12-26 | 1999-03-02 | Cornell Research Foundation, Inc. | Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis |
| US5354885A (en) * | 1992-12-24 | 1994-10-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Process for preparing ethyl ester of L-DOPA |
| SE512655C2 (sv) * | 1993-11-17 | 2000-04-17 | Medmera Sweden Hb C O Nil Dizd | Infusionslösning för medicinskt bruk innehållande L-dopa |
| JP3865450B2 (ja) | 1997-02-14 | 2007-01-10 | 田辺製薬株式会社 | パーキンソニズム治療剤 |
| FR2777781B1 (fr) * | 1998-04-24 | 2004-04-09 | Rhone Poulenc Rorer Sa | Associations riluzole et l-dopa pour le traitement de la maladie de parkinson |
| FI109453B (fi) | 1999-06-30 | 2002-08-15 | Orion Yhtymae Oyj | Farmaseuttinen koostumus |
| DE10261808A1 (de) * | 2002-12-19 | 2004-07-08 | Turicum Drug Development Ag | Verwendung von L-DOPA, seiner Derivate und diese Verbindungen enthaltender Arzneimittel zur Prophylaxe psychotischer Erkrankungen |
| ATE495739T1 (de) | 2003-08-29 | 2011-02-15 | Transform Pharmaceuticals Inc | Pharmazeutische zusammensetzungen und verfahren zur verwendung von levodopa und carbidopa |
-
2004
- 2004-07-12 SE SE0401842A patent/SE0401842D0/xx unknown
-
2005
- 2005-07-08 PT PT57570665T patent/PT1773297E/pt unknown
- 2005-07-08 EP EP05757066.5A patent/EP1773297B1/en not_active Expired - Lifetime
- 2005-07-08 AU AU2005262918A patent/AU2005262918B2/en not_active Ceased
- 2005-07-08 EA EA200700020A patent/EA012415B1/ru not_active IP Right Cessation
- 2005-07-08 ZA ZA200700993A patent/ZA200700993B/xx unknown
- 2005-07-08 WO PCT/SE2005/001135 patent/WO2006006929A1/en not_active Ceased
- 2005-07-08 PL PL05757066T patent/PL1773297T3/pl unknown
- 2005-07-08 MX MX2007000406A patent/MX2007000406A/es active IP Right Grant
- 2005-07-08 CA CA2574437A patent/CA2574437C/en not_active Expired - Fee Related
- 2005-07-08 JP JP2007521433A patent/JP2008505966A/ja active Pending
- 2005-07-08 KR KR1020077003232A patent/KR20070042172A/ko not_active Ceased
- 2005-07-08 SI SI200531958T patent/SI1773297T1/sl unknown
- 2005-07-08 EP EP10181105.7A patent/EP2298281B1/en not_active Expired - Lifetime
- 2005-07-08 DK DK05757066T patent/DK1773297T3/en active
- 2005-07-08 HR HRP20150384TT patent/HRP20150384T1/hr unknown
- 2005-07-08 CN CN200580029688.5A patent/CN101022784B/zh not_active Expired - Fee Related
- 2005-07-08 BR BRPI0513293-2A patent/BRPI0513293A/pt not_active Application Discontinuation
- 2005-07-08 US US11/631,602 patent/US20080255235A1/en not_active Abandoned
- 2005-07-08 ES ES05757066.5T patent/ES2534596T3/es not_active Expired - Lifetime
- 2005-07-08 MX MX2013006111A patent/MX349829B/es unknown
-
2007
- 2007-01-11 IL IL180650A patent/IL180650A/en active IP Right Grant
-
2011
- 2011-08-12 US US13/208,628 patent/US8735382B2/en not_active Expired - Lifetime
-
2012
- 2012-08-23 JP JP2012183865A patent/JP2013028609A/ja active Pending
-
2014
- 2014-04-14 US US14/251,967 patent/US9248113B2/en not_active Expired - Lifetime
-
2015
- 2015-04-09 CY CY20151100347T patent/CY1116197T1/el unknown
- 2015-06-24 JP JP2015126946A patent/JP2015227341A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |