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MA53623A - Procédés de traitement du cancer par inhibition de l'enzyme de conjugaison de l'ubiquitine e2 k (ube2k) - Google Patents

Procédés de traitement du cancer par inhibition de l'enzyme de conjugaison de l'ubiquitine e2 k (ube2k)

Info

Publication number
MA53623A
MA53623A MA053623A MA53623A MA53623A MA 53623 A MA53623 A MA 53623A MA 053623 A MA053623 A MA 053623A MA 53623 A MA53623 A MA 53623A MA 53623 A MA53623 A MA 53623A
Authority
MA
Morocco
Prior art keywords
ube2k
inhibition
cancer
treatment
methods
Prior art date
Application number
MA053623A
Other languages
English (en)
Inventor
Anne R Diers
Stephane Gesta
Vivek K Vishnudas
Original Assignee
Berg Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berg Llc filed Critical Berg Llc
Publication of MA53623A publication Critical patent/MA53623A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • A61K31/277Nitriles; Isonitriles having a ring, e.g. verapamil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001154Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
MA053623A 2018-09-10 2019-09-10 Procédés de traitement du cancer par inhibition de l'enzyme de conjugaison de l'ubiquitine e2 k (ube2k) MA53623A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862729348P 2018-09-10 2018-09-10

Publications (1)

Publication Number Publication Date
MA53623A true MA53623A (fr) 2021-07-21

Family

ID=69778426

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053623A MA53623A (fr) 2018-09-10 2019-09-10 Procédés de traitement du cancer par inhibition de l'enzyme de conjugaison de l'ubiquitine e2 k (ube2k)

Country Status (13)

Country Link
US (1) US20210252036A1 (fr)
EP (1) EP3849543A4 (fr)
JP (2) JP2022500378A (fr)
KR (1) KR20210057121A (fr)
CN (1) CN112996504A (fr)
AU (1) AU2019339896A1 (fr)
BR (1) BR112021004417A2 (fr)
CA (1) CA3112191A1 (fr)
IL (1) IL281327A (fr)
MA (1) MA53623A (fr)
MX (1) MX2021002818A (fr)
SG (1) SG11202102417TA (fr)
WO (1) WO2020055906A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3166630A1 (fr) * 2020-01-03 2021-07-08 Berg Llc Amides polycycliques utilises en tant que modulateurs d'ube2k pour le traitement du cancer
JP2024543111A (ja) * 2021-11-17 2024-11-19 ビーピージーバイオ,インコーポレイテッド 胃がんの治療に使用するための化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2576702C (fr) * 2004-08-11 2016-10-04 Albert Einstein College Of Medicine Of Yeshiva University Isolation, expression genique et resistance chimiotherapeutique de cellules cancereuses motiles
CN101583622B (zh) * 2006-11-02 2012-11-07 舒泰神(北京)生物制药股份有限公司 用于破坏与泛素化相关的酶的相互作用的抑制剂和其应用
KR100919832B1 (ko) * 2009-05-15 2009-10-01 고려대학교 산학협력단 Hip―2 유전자 발현을 억제하여 암세포의 방사선에 대한 민감도를 증진하는 방법
WO2014094138A1 (fr) * 2012-12-21 2014-06-26 Universite De Montreal Procédés de criblage pour l'identification de composés inhibiteurs de l'activité d'enzymes e2 par la stabilisation de complexes ubiquitine-e2 non covalents et applications pharmaceutiques associées aux inhibiteurs d'e2
KR101525122B1 (ko) * 2013-08-05 2015-06-03 광주과학기술원 Ubb 넉­다운에 의한 암의 예방 또는 치료
JP6447933B2 (ja) * 2014-02-21 2019-01-09 アイビーシー ファーマスーティカルズ,インコーポレイテッド Trop−2発現細胞に対する免疫応答を誘発することによる疾患治療
JP6647315B2 (ja) * 2015-01-09 2020-02-14 イーチュービクス コーポレイション 組み合わせ免疫療法のための方法および組成物

Also Published As

Publication number Publication date
MX2021002818A (es) 2021-07-15
JP2025003968A (ja) 2025-01-14
JP2022500378A (ja) 2022-01-04
EP3849543A1 (fr) 2021-07-21
IL281327A (en) 2021-04-29
BR112021004417A2 (pt) 2021-06-01
WO2020055906A8 (fr) 2021-01-07
WO2020055906A1 (fr) 2020-03-19
US20210252036A1 (en) 2021-08-19
AU2019339896A1 (en) 2021-04-08
CN112996504A (zh) 2021-06-18
SG11202102417TA (en) 2021-04-29
EP3849543A4 (fr) 2022-11-30
KR20210057121A (ko) 2021-05-20
CA3112191A1 (fr) 2020-03-19

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