MA49635A - Compositions comprenant du darunavir, du cobicistat, de l'emtricitabine et du ténofovir alafénamide pour une utilisation dans le traitement du vih - Google Patents
Compositions comprenant du darunavir, du cobicistat, de l'emtricitabine et du ténofovir alafénamide pour une utilisation dans le traitement du vihInfo
- Publication number
- MA49635A MA49635A MA049635A MA49635A MA49635A MA 49635 A MA49635 A MA 49635A MA 049635 A MA049635 A MA 049635A MA 49635 A MA49635 A MA 49635A MA 49635 A MA49635 A MA 49635A
- Authority
- MA
- Morocco
- Prior art keywords
- cobicistat
- darunavir
- emtricitabine
- hiv
- treatment
- Prior art date
Links
- ZCIGNRJZKPOIKD-CQXVEOKZSA-N cobicistat Chemical compound S1C(C(C)C)=NC(CN(C)C(=O)N[C@@H](CCN2CCOCC2)C(=O)N[C@H](CC[C@H](CC=2C=CC=CC=2)NC(=O)OCC=2SC=NC=2)CC=2C=CC=CC=2)=C1 ZCIGNRJZKPOIKD-CQXVEOKZSA-N 0.000 title 1
- 229960002402 cobicistat Drugs 0.000 title 1
- CJBJHOAVZSMMDJ-HEXNFIEUSA-N darunavir Chemical compound C([C@@H]([C@H](O)CN(CC(C)C)S(=O)(=O)C=1C=CC(N)=CC=1)NC(=O)O[C@@H]1[C@@H]2CCO[C@@H]2OC1)C1=CC=CC=C1 CJBJHOAVZSMMDJ-HEXNFIEUSA-N 0.000 title 1
- 229960005107 darunavir Drugs 0.000 title 1
- 229940120915 emtricitabine and tenofovir alafenamide Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762534885P | 2017-07-20 | 2017-07-20 | |
| US201762571384P | 2017-10-12 | 2017-10-12 | |
| US201862623174P | 2018-01-29 | 2018-01-29 | |
| US201862665339P | 2018-05-01 | 2018-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA49635A true MA49635A (fr) | 2020-05-27 |
Family
ID=63168494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA049635A MA49635A (fr) | 2017-07-20 | 2018-07-19 | Compositions comprenant du darunavir, du cobicistat, de l'emtricitabine et du ténofovir alafénamide pour une utilisation dans le traitement du vih |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10786518B2 (fr) |
| EP (1) | EP3654951A1 (fr) |
| JP (2) | JP2020528409A (fr) |
| AU (1) | AU2018304373B2 (fr) |
| BR (1) | BR112020000842A2 (fr) |
| CA (1) | CA3070713A1 (fr) |
| CL (1) | CL2020000136A1 (fr) |
| MA (1) | MA49635A (fr) |
| MX (1) | MX2020000694A (fr) |
| WO (1) | WO2019018676A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021180963A1 (fr) * | 2020-03-13 | 2021-09-16 | Janssen Sciences Ireland Unlimited Company | Régime inhibiteur de protéase pour traiter des sujets infectés par le vih |
| CN111419811A (zh) * | 2020-05-20 | 2020-07-17 | 北京华睿鼎信科技有限公司 | 一种富马酸替诺福韦艾拉酚胺组合物 |
| CN119700779B (zh) * | 2024-11-28 | 2025-11-04 | 安徽贝克生物制药有限公司 | 一种达芦那韦和考比司他复合片剂及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI471145B (zh) * | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
| US20140142070A1 (en) | 2011-07-07 | 2014-05-22 | Janssen R&D Ireland | Darunavir combination formulations |
| PL2729128T3 (pl) | 2011-07-07 | 2017-05-31 | Janssen Sciences Ireland Uc | Preparat darunawiru |
| AU2012327170A1 (en) | 2012-02-03 | 2013-08-22 | Gilead Sciences, Inc. | Therapeutic compounds |
| BR112017014085A2 (pt) * | 2015-01-03 | 2018-01-09 | Mylan Laboratories Ltd | processos para a preparação de hemifumarato de tenofovir alafenamida amorfo e uma pré-mistura do mesmo |
-
2018
- 2018-07-19 WO PCT/US2018/042937 patent/WO2019018676A1/fr not_active Ceased
- 2018-07-19 MA MA049635A patent/MA49635A/fr unknown
- 2018-07-19 AU AU2018304373A patent/AU2018304373B2/en active Active
- 2018-07-19 MX MX2020000694A patent/MX2020000694A/es unknown
- 2018-07-19 CA CA3070713A patent/CA3070713A1/fr active Pending
- 2018-07-19 EP EP18753288.2A patent/EP3654951A1/fr active Pending
- 2018-07-19 JP JP2020502405A patent/JP2020528409A/ja not_active Withdrawn
- 2018-07-19 US US16/040,324 patent/US10786518B2/en active Active
- 2018-07-19 BR BR112020000842-7A patent/BR112020000842A2/pt not_active Application Discontinuation
-
2020
- 2020-01-16 CL CL2020000136A patent/CL2020000136A1/es unknown
-
2023
- 2023-06-07 JP JP2023093929A patent/JP2023123523A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018304373B2 (en) | 2024-08-01 |
| JP2020528409A (ja) | 2020-09-24 |
| US10786518B2 (en) | 2020-09-29 |
| CL2020000136A1 (es) | 2020-06-12 |
| CA3070713A1 (fr) | 2019-01-24 |
| JP2023123523A (ja) | 2023-09-05 |
| EP3654951A1 (fr) | 2020-05-27 |
| US20190022113A1 (en) | 2019-01-24 |
| BR112020000842A2 (pt) | 2020-07-21 |
| MX2020000694A (es) | 2020-07-29 |
| WO2019018676A1 (fr) | 2019-01-24 |
| AU2018304373A1 (en) | 2020-01-30 |
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