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MA47167A - Composés pyrazolopyrimidine et leurs procédés d'utilisation - Google Patents

Composés pyrazolopyrimidine et leurs procédés d'utilisation

Info

Publication number
MA47167A
MA47167A MA047167A MA47167A MA47167A MA 47167 A MA47167 A MA 47167A MA 047167 A MA047167 A MA 047167A MA 47167 A MA47167 A MA 47167A MA 47167 A MA47167 A MA 47167A
Authority
MA
Morocco
Prior art keywords
methods
pyrazolopyrimidine compounds
pyrazolopyrimidine
compounds
Prior art date
Application number
MA047167A
Other languages
English (en)
Inventor
Limin Cheng
Yun-Xing Cheng
Paul Gibbons
Wei Li
F Anthony Romero
Po-Wai Yuen
Mark Zak
Guiling Zhao
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA47167A publication Critical patent/MA47167A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MA047167A 2016-12-29 2017-12-22 Composés pyrazolopyrimidine et leurs procédés d'utilisation MA47167A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2016112932 2016-12-29

Publications (1)

Publication Number Publication Date
MA47167A true MA47167A (fr) 2019-11-06

Family

ID=61094385

Family Applications (1)

Application Number Title Priority Date Filing Date
MA047167A MA47167A (fr) 2016-12-29 2017-12-22 Composés pyrazolopyrimidine et leurs procédés d'utilisation

Country Status (19)

Country Link
US (1) US11155557B2 (fr)
EP (1) EP3562809B1 (fr)
JP (1) JP6900491B2 (fr)
KR (1) KR20190100337A (fr)
CN (1) CN110114343B (fr)
AU (1) AU2017385543A1 (fr)
BR (1) BR112019013287A2 (fr)
CA (1) CA3046435A1 (fr)
CL (1) CL2019001694A1 (fr)
CO (1) CO2019006220A2 (fr)
CR (1) CR20190310A (fr)
IL (1) IL267671A (fr)
MA (1) MA47167A (fr)
MX (1) MX2019007339A (fr)
PE (1) PE20191236A1 (fr)
PH (1) PH12019501022A1 (fr)
RU (1) RU2019123319A (fr)
UA (1) UA122851C2 (fr)
WO (1) WO2018122212A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3046435A1 (fr) 2016-12-29 2018-07-05 F. Hoffmann-La Roche Ag Composes pyrazolopyrimidine et leurs procedes d'utilisation
CR20190520A (es) 2017-05-22 2020-01-21 Hoffmann La Roche Composiciones y compuestos terapéuticos y métodos para utilizarlos
CN111587250A (zh) * 2018-01-15 2020-08-25 豪夫迈·罗氏有限公司 作为jak抑制剂的吡唑并嘧啶化合物
CN114008050B (zh) * 2019-06-18 2024-12-31 豪夫迈·罗氏有限公司 Jak激酶的吡唑并嘧啶芳基醚抑制剂及其用途
AU2020297415A1 (en) 2019-06-18 2022-01-06 F. Hoffmann-La Roche Ag Pyrazolopyrimidine sulfone inhibitors of JAK kinases and uses thereof
US20200399274A1 (en) * 2019-06-18 2020-12-24 Genentech, Inc. Tetrazole-substituted pyrazolopyrimidine inhibitors of jak kinases and uses thereof
WO2022175829A1 (fr) * 2021-02-17 2022-08-25 Cellix Bio Private Limited Formulations et compositions topiques
PE20251394A1 (es) * 2022-09-09 2025-05-22 Chiesi Farm Spa Derivados heterociclicos como inhibidores de cinasa janus
CN120051476A (zh) * 2022-09-09 2025-05-27 奇斯药制品公司 作为janus激酶抑制剂的杂环衍生物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
US5543523A (en) 1994-11-15 1996-08-06 Regents Of The University Of Minnesota Method and intermediates for the synthesis of korupensamines
WO1997002289A1 (fr) 1995-07-06 1997-01-23 Zeneca Limited Inhibiteurs peptidiques de la fibronectine
US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
YU25500A (sh) 1999-05-11 2003-08-29 Pfizer Products Inc. Postupak za sintezu analoga nukleozida
GB0028383D0 (en) 2000-11-21 2001-01-03 Novartis Ag Organic compounds
EP1241176A1 (fr) 2001-03-16 2002-09-18 Pfizer Products Inc. Dérivés de purine pour le traitement de l'ischémie
US7199136B2 (en) 2001-12-20 2007-04-03 Bayer Healthcare Ag 1,4-dihydro-1,4-diphenylpyridine derivatives
SE0302487D0 (sv) 2003-09-18 2003-09-18 Astrazeneca Ab Novel compounds
GB0502258D0 (en) 2005-02-03 2005-03-09 Argenta Discovery Ltd Compounds and their use
CN102127078A (zh) 2005-07-14 2011-07-20 安斯泰来制药株式会社 Janus激酶3的杂环类抑制剂
KR20110033223A (ko) 2008-06-20 2011-03-30 제넨테크, 인크. 트리아졸로피리딘 jak 억제제 화합물 및 방법
UA110324C2 (en) * 2009-07-02 2015-12-25 Genentech Inc Jak inhibitory compounds based on pyrazolo pyrimidine
US8575336B2 (en) 2011-07-27 2013-11-05 Pfizer Limited Indazoles
UA121658C2 (uk) 2014-05-23 2020-07-10 Ф. Хоффманн-Ля Рош Аг Сполуки 5-хлордифторметоксифенілпіразолопіримідину як інгібітори янус-кінази
TW201720828A (zh) 2015-11-23 2017-06-16 赫孚孟拉羅股份公司 治療性化合物及組合物以及其使用方法
EP3416967B1 (fr) 2016-02-18 2022-02-09 F. Hoffmann-La Roche AG Composés thérapeutiques, leurs compositions et méthodes d'utilisation
JP7208020B2 (ja) 2016-06-29 2023-01-18 ハンミ ファーマシューティカル カンパニー リミテッド グルカゴン誘導体、その結合体、及びそれを含む組成物、並びにその治療的用途
CA3046435A1 (fr) 2016-12-29 2018-07-05 F. Hoffmann-La Roche Ag Composes pyrazolopyrimidine et leurs procedes d'utilisation

Also Published As

Publication number Publication date
IL267671A (en) 2019-08-29
AU2017385543A1 (en) 2019-05-23
BR112019013287A2 (pt) 2019-12-24
RU2019123319A (ru) 2021-02-01
KR20190100337A (ko) 2019-08-28
CL2019001694A1 (es) 2019-11-22
CN110114343A (zh) 2019-08-09
EP3562809A1 (fr) 2019-11-06
CN110114343B (zh) 2022-09-06
CA3046435A1 (fr) 2018-07-05
WO2018122212A1 (fr) 2018-07-05
CR20190310A (es) 2019-08-21
US11155557B2 (en) 2021-10-26
PH12019501022A1 (en) 2019-12-16
UA122851C2 (uk) 2021-01-06
CO2019006220A2 (es) 2019-06-28
EP3562809B1 (fr) 2021-06-09
JP2020503339A (ja) 2020-01-30
US20190345165A1 (en) 2019-11-14
JP6900491B2 (ja) 2021-07-07
RU2019123319A3 (fr) 2021-02-01
PE20191236A1 (es) 2019-09-11
MX2019007339A (es) 2019-09-06

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