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MA44869A - Cellules génétiquement modifiées et leurs procédés de fabrication - Google Patents

Cellules génétiquement modifiées et leurs procédés de fabrication

Info

Publication number
MA44869A
MA44869A MA044869A MA44869A MA44869A MA 44869 A MA44869 A MA 44869A MA 044869 A MA044869 A MA 044869A MA 44869 A MA44869 A MA 44869A MA 44869 A MA44869 A MA 44869A
Authority
MA
Morocco
Prior art keywords
genetically modified
manufacturing processes
modified cells
cells
processes
Prior art date
Application number
MA044869A
Other languages
English (en)
Inventor
David A Bumcrot
Ari E Friedland
Jon Jones
Morgan L Maeder
Chris Nye
Eugenio Marco Rubio
Ruth Salmon
Blythe Sather
G Grant Welstead
Original Assignee
Editas Medicine Inc
Juno Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Editas Medicine Inc, Juno Therapeutics Inc filed Critical Editas Medicine Inc
Publication of MA44869A publication Critical patent/MA44869A/fr

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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WO2017193107A2 (fr) 2017-11-09
IL302641A (en) 2023-07-01
US20190136230A1 (en) 2019-05-09
IL262772B1 (en) 2023-06-01
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EP3452499A2 (fr) 2019-03-13
KR20190038479A (ko) 2019-04-08
IL262772A (en) 2018-12-31
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JP2019517788A (ja) 2019-06-27
CN109843915B (zh) 2023-03-03
JP2023061884A (ja) 2023-05-02
AU2017261380A1 (en) 2018-11-22
IL262772B2 (en) 2023-10-01
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CN116850305A (zh) 2023-10-10
CA3022611A1 (fr) 2017-11-09

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