MA42592A - Utilisation de dérivés de 2-(pyrazolopyridin-3-yl) pyrimidine en tant qu'inhibiteurs de jak - Google Patents

Utilisation de dérivés de 2-(pyrazolopyridin-3-yl) pyrimidine en tant qu'inhibiteurs de jak

Info

Publication number: MA42592A
Authority: MA; Morocco
Prior art keywords: pyrazolopyridin; pyrimidine derivatives; jak inhibitors; jak; inhibitors
Prior art date: 2015-06-11

Application number

MA042592A

Other languages

English (en)

Inventor

Trias Cristina Esteve

Rodriguez Jacob Gonzalez

Moll Joan Taltavull

Juan Bernat Vidal

Original Assignee

Almirall Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-06-11

Filing date

2016-06-10

Publication date

2018-06-20

2016-06-10 Application filed by Almirall Sa filed Critical Almirall Sa

2018-06-20 Publication of MA42592A publication Critical patent/MA42592A/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Hematology (AREA)
Immunology (AREA)
Dermatology (AREA)
Ophthalmology & Optometry (AREA)
Neurology (AREA)
Epidemiology (AREA)
Obesity (AREA)
Physical Education & Sports Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Oncology (AREA)
Orthopedic Medicine & Surgery (AREA)
Otolaryngology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

MA042592A 2015-06-11 2016-06-10 Utilisation de dérivés de 2-(pyrazolopyridin-3-yl) pyrimidine en tant qu'inhibiteurs de jak MA42592A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP15382305		2015-06-11

Publications (1)

Publication Number	Publication Date
MA42592A true MA42592A (fr)	2018-06-20

Family

ID=53476802

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA042592A MA42592A (fr)	2015-06-11	2016-06-10	Utilisation de dérivés de 2-(pyrazolopyridin-3-yl) pyrimidine en tant qu'inhibiteurs de jak

Country Status (22)

Country	Link
US (1)	US10759793B2 (fr)
EP (1)	EP3307272A1 (fr)
JP (1)	JP2018516954A (fr)
KR (1)	KR20180012854A (fr)
CN (1)	CN107667106A (fr)
AR (1)	AR104963A1 (fr)
AU (1)	AU2016275716C1 (fr)
BR (1)	BR112017025781A2 (fr)
CA (1)	CA2987328A1 (fr)
CL (1)	CL2017003107A1 (fr)
CO (1)	CO2017011996A2 (fr)
CR (1)	CR20170557A (fr)
EA (1)	EA035312B1 (fr)
HK (1)	HK1246667A1 (fr)
IL (1)	IL255668A (fr)
MA (1)	MA42592A (fr)
MX (1)	MX2017015029A (fr)
PE (1)	PE20180279A1 (fr)
PH (1)	PH12017502236A1 (fr)
SG (1)	SG10201911926UA (fr)
TW (1)	TW201705961A (fr)
WO (1)	WO2016198663A1 (fr)

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CN116327923A (zh)	2015-08-24	2023-06-27	葛兰素史密斯克莱知识产权（第2 号）有限公司	生物医药组合物
BR112018016300A2 (pt) *	2016-02-12	2018-12-26	Univ Zuerich	fumarato de dimetila (dmf) para prevenção ou tratamento de gota, acne, diabetes, vitiligo e/ou pioderma gangrenoso
KR102460040B1 (ko)	2016-04-27	2022-11-01	애브비 인코포레이티드	항-il-13 항체를 이용한 il-13 활성이 유해한 질환의 치료 방법
CN110088100B (zh) *	2016-11-08	2023-02-17	癌症研究科技有限公司	作为cdc7抑制剂的嘧啶酮衍生物
US20180235931A1 (en) *	2017-01-17	2018-08-23	Menlo Therapeutics Inc.	Use of neurokinin-1 antagonists as antitussives
US11311548B2 (en)	2017-03-02	2022-04-26	Aslan Pharmaceuticals Pte. Ltd.	Cancer therapy
WO2018160138A1 (fr) *	2017-03-02	2018-09-07	Aslan Pharmaceuticals Pte Ltd	Inhibiteur de dhodh pour le traitement du cancer hématologique
WO2018200786A1 (fr) *	2017-04-26	2018-11-01	Yale University	Compositions et méthodes pour traiter le vitiligo
CN108514637A (zh) *	2018-05-07	2018-09-11	山东省眼科研究所	Stat3抑制剂s31-201在治疗干眼症中的应用
CN109810991B (zh) *	2019-03-02	2021-11-12	昆明理工大学	二氢蝶酸合酶基因folP的用途
AU2021242143B2 (en) *	2020-03-27	2024-07-18	Dong-A St Co., Ltd.	Aminopyrimidine derivatives and their use as Aryl hydrocarbon receptor modulators
IL298589A (en) *	2020-06-02	2023-01-01	Nerre Therapeutics Ltd	Neurokinin (nk)-1 receptor antagonists for use in the treatment of pulmonary fibrosis conditions promoted by mechanical injury to the lungs
JP2024508794A (ja)	2021-02-19	2024-02-28	スドーバイオサイエンシーズリミテッド	Ｔｙｋ２阻害剤およびその使用
CA3207819A1 (fr)	2021-02-19	2022-08-25	Anjali Pandey	Inhibiteurs de tyk2 et leurs utilisations
FI4333840T3 (fi) *	2021-05-03	2025-12-12	Incyte Corp	Jak1-reitin estäjiä kyhmykutinan hoitoon
CA3224068A1 (fr) *	2021-07-30	2023-02-02	Eli Lilly And Company	Traitement de l'eczema des mains a l'aide de baricitinib
WO2025095039A1 (fr) *	2023-10-31	2025-05-08	ティア・リサーチ・コンサルティング合同会社	Composition pharmaceutique pour maladies de la peau et procédé de recherche d'une nouvelle utilisation de médicament
CN119707992B (zh) *	2024-12-20	2025-12-09	杭州同舟生物技术有限公司	一种纳呋拉啡人工半抗原、人工抗原及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS54128591A (en)	1978-03-25	1979-10-05	Kyowa Hakko Kogyo Co Ltd	Cephalosporin analog
EP2338888A1 (fr) *	2009-12-24	2011-06-29	Almirall, S.A.	Dérivés d'imidazopyridine en tant qu'inhibiteurs JAK
UY33213A (es) *	2010-02-18	2011-09-30	Almirall Sa	Derivados de pirazol como inhibidores de jak
EP2397482A1 (fr)	2010-06-15	2011-12-21	Almirall, S.A.	Dérivés d'imidazolone d'hétéroaryle en tant qu'inhibiteurs de JAK
AR086042A1 (es) *	2011-04-28	2013-11-13	Galapagos Nv	Compuesto util para el tratamiento de enfermedades degenerativas e inflamatorias y composicion farmaceutica
WO2013025628A1 (fr) *	2011-08-15	2013-02-21	Ligand Pharmaceuticals Incorporated	Composés et procédés d'inhibition de janus kinase
JP6014148B2 (ja) *	2011-09-22	2016-10-25	メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋＳｈａｒｐ＆ＤｏｈｍｅＣｏｒｐ．	ヤヌスキナーゼ阻害剤としてのシクロアルキルニトリルピラゾールカルボキサミド
TW201605811A (zh)	2013-12-11	2016-02-16	阿爾米雷爾有限公司	作為jak抑制劑之吡唑并嘧啶-2基衍生物

2016
- 2016-06-08 TW TW105118168A patent/TW201705961A/zh unknown
- 2016-06-10 EP EP16728326.6A patent/EP3307272A1/fr not_active Withdrawn
- 2016-06-10 HK HK18106235.2A patent/HK1246667A1/zh unknown
- 2016-06-10 SG SG10201911926UA patent/SG10201911926UA/en unknown
- 2016-06-10 CA CA2987328A patent/CA2987328A1/fr not_active Abandoned
- 2016-06-10 MX MX2017015029A patent/MX2017015029A/es unknown
- 2016-06-10 AR ARP160101733A patent/AR104963A1/es unknown
- 2016-06-10 EA EA201792689A patent/EA035312B1/ru not_active IP Right Cessation
- 2016-06-10 BR BR112017025781-5A patent/BR112017025781A2/pt not_active Application Discontinuation
- 2016-06-10 AU AU2016275716A patent/AU2016275716C1/en not_active Ceased
- 2016-06-10 JP JP2017563955A patent/JP2018516954A/ja active Pending
- 2016-06-10 WO PCT/EP2016/063391 patent/WO2016198663A1/fr not_active Ceased
- 2016-06-10 KR KR1020187000866A patent/KR20180012854A/ko not_active Withdrawn
- 2016-06-10 MA MA042592A patent/MA42592A/fr unknown
- 2016-06-10 US US15/735,235 patent/US10759793B2/en not_active Expired - Fee Related
- 2016-06-10 CN CN201680030333.6A patent/CN107667106A/zh active Pending
- 2016-06-10 PE PE2017002479A patent/PE20180279A1/es unknown
- 2016-06-10 CR CR20170557A patent/CR20170557A/es unknown
2017
- 2017-11-14 IL IL255668A patent/IL255668A/en unknown
- 2017-11-27 CO CONC2017/0011996A patent/CO2017011996A2/es unknown
- 2017-12-05 CL CL2017003107A patent/CL2017003107A1/es unknown
- 2017-12-07 PH PH12017502236A patent/PH12017502236A1/en unknown

Also Published As

Publication number	Publication date
AU2016275716A1 (en)	2017-12-07
JP2018516954A (ja)	2018-06-28
CL2017003107A1 (es)	2018-04-02
WO2016198663A1 (fr)	2016-12-15
US10759793B2 (en)	2020-09-01
MX2017015029A (es)	2018-04-13
EP3307272A1 (fr)	2018-04-18
BR112017025781A2 (pt)	2018-08-14
EA035312B1 (ru)	2020-05-27
AU2016275716B2 (en)	2020-01-23
AU2016275716C1 (en)	2020-10-15
HK1246667A1 (zh)	2018-09-14
CA2987328A1 (fr)	2016-12-15
KR20180012854A (ko)	2018-02-06
CO2017011996A2 (es)	2018-03-28
SG10201911926UA (en)	2020-01-30
PE20180279A1 (es)	2018-02-07
EA201792689A1 (ru)	2018-07-31
CR20170557A (es)	2018-02-06
US20180162856A1 (en)	2018-06-14
PH12017502236A1 (en)	2018-06-11
CN107667106A (zh)	2018-02-06
TW201705961A (zh)	2017-02-16
NZ737314A (en)	2021-02-26
IL255668A (en)	2018-01-31
AR104963A1 (es)	2017-08-30

Publication	Publication Date	Title
MA42592A (fr)	2018-06-20	Utilisation de dérivés de 2-(pyrazolopyridin-3-yl) pyrimidine en tant qu'inhibiteurs de jak
MA51878A (fr)	2020-12-30	Composés d'aminothiazole en tant qu'inhibiteurs de c-kit
MA40587A (fr)	2017-06-28	Composés d'aminopyrimidinyle en tant qu'inhibiteurs de jak
MA43169A (fr)	2018-09-12	Composés hétérocycliques utilisés en tant qu'inhibiteurs de pi3k-gamma
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