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MA39927A - Inhibiteurs de glyt1 pour le traitement de troubles hématologiques - Google Patents

Inhibiteurs de glyt1 pour le traitement de troubles hématologiques

Info

Publication number
MA39927A
MA39927A MA039927A MA39927A MA39927A MA 39927 A MA39927 A MA 39927A MA 039927 A MA039927 A MA 039927A MA 39927 A MA39927 A MA 39927A MA 39927 A MA39927 A MA 39927A
Authority
MA
Morocco
Prior art keywords
treatment
blood disorders
glyt1 inhibitors
glyt1
inhibitors
Prior art date
Application number
MA039927A
Other languages
English (en)
Other versions
MA39927B1 (fr
Inventor
Daniela Alberati
Annette Koerner
Emmanuel Pinard
Michael Winter
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA39927A publication Critical patent/MA39927A/fr
Publication of MA39927B1 publication Critical patent/MA39927B1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MA39927A 2014-04-30 2015-04-27 Inhibiteurs de glyt1 pour le traitement de troubles hématologiques MA39927B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14166497 2014-04-30
EP15717916.9A EP3137073B1 (fr) 2014-04-30 2015-04-27 Inhibiteurs de glyt1 pour le traitement de troubles hématologiques
PCT/EP2015/059037 WO2015165842A1 (fr) 2014-04-30 2015-04-27 Inhibiteurs de glyt1 destinés à être utilisés dans le traitement de troubles hématologiques

Publications (2)

Publication Number Publication Date
MA39927A true MA39927A (fr) 2017-03-08
MA39927B1 MA39927B1 (fr) 2018-09-28

Family

ID=50677958

Family Applications (1)

Application Number Title Priority Date Filing Date
MA39927A MA39927B1 (fr) 2014-04-30 2015-04-27 Inhibiteurs de glyt1 pour le traitement de troubles hématologiques

Country Status (18)

Country Link
US (1) US9877963B2 (fr)
EP (1) EP3137073B1 (fr)
JP (1) JP6283766B2 (fr)
KR (1) KR101869185B1 (fr)
CN (1) CN106163520B (fr)
AR (1) AR100209A1 (fr)
CY (1) CY1120508T1 (fr)
ES (1) ES2683184T3 (fr)
HR (1) HRP20181205T1 (fr)
MA (1) MA39927B1 (fr)
MY (1) MY189930A (fr)
PH (1) PH12016501784B1 (fr)
PT (1) PT3137073T (fr)
RS (1) RS57535B1 (fr)
SG (2) SG10201909382UA (fr)
SI (1) SI3137073T1 (fr)
TR (1) TR201809598T4 (fr)
WO (1) WO2015165842A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3199156A1 (fr) * 2016-02-01 2017-08-02 Heinrich-Heine-Universität Düsseldorf Utilisation d'antagonistes du transporteur de la glycine 1 comme analgésiques du systeme nerveux central
CU20200106A7 (es) * 2018-06-20 2021-08-06 Axcella Health Inc Composiciones y métodos para el tratamiento de hemoglobinopatías y talasemias
CA3166938A1 (fr) * 2020-01-09 2021-07-15 Disc Medicine, Inc. Methodes de traitement de protoporphyrie erythropoietique, de protoporphyrie liee a x ou de porphyrie erythropoietique congenitale avec des inhibiteurs de transport de glycine
EP4304597A4 (fr) * 2021-03-12 2025-02-19 Disc Medicine, Inc. Compositions et méthodes de traitement de l'anémie associée à un trouble ribosomique
JP2024518091A (ja) * 2021-05-14 2024-04-24 ディスク・メディシン・インコーポレイテッド グリシン輸送阻害剤を用いて赤血球増殖性プロトポルフィリン症、x連鎖プロトポルフィリン症または先天性赤血球増殖性ポルフィリン症を処置する方法
JP2024520391A (ja) * 2021-05-27 2024-05-24 ディスク・メディシン・インコーポレイテッド ビトペルチンの固体形態を用いて赤血球増殖性プロトポルフィリン症、x連鎖プロトポルフィリン症または先天性赤血球増殖性ポルフィリン症を処置する方法
WO2023235326A1 (fr) * 2022-05-31 2023-12-07 Disc Medicine, Inc. Compositions et méthodes de traitement de porphyries hépatiques avec des inhibiteurs de transport de glycine
WO2025059425A1 (fr) * 2023-09-15 2025-03-20 Disc Medicine, Inc. Inhibiteurs de glyt-1 et leurs utilisations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS53252B (sr) * 2003-08-11 2014-08-29 F.Hoffmann-La Roche Ag. Piperazin sa or-supstituisanom fenil grupom i njihova upotreba kao inhibitora glyt1
HRP20100076T1 (hr) * 2005-02-07 2010-03-31 F. Hoffmann - La Roche Ag Heterociklički supstituirani fenil metanoni kao inhibitori glicin transportera 1

Also Published As

Publication number Publication date
WO2015165842A1 (fr) 2015-11-05
EP3137073B1 (fr) 2018-06-06
PT3137073T (pt) 2018-07-27
TR201809598T4 (tr) 2018-07-23
CN106163520B (zh) 2019-12-13
SG11201608397UA (en) 2016-11-29
CY1120508T1 (el) 2019-07-10
JP2017511385A (ja) 2017-04-20
SG10201909382UA (en) 2019-11-28
MA39927B1 (fr) 2018-09-28
ES2683184T3 (es) 2018-09-25
CN106163520A (zh) 2016-11-23
KR20160130517A (ko) 2016-11-11
HRP20181205T1 (hr) 2018-09-21
EP3137073A1 (fr) 2017-03-08
US9877963B2 (en) 2018-01-30
SI3137073T1 (sl) 2018-09-28
RS57535B1 (sr) 2018-10-31
PH12016501784A1 (en) 2016-11-07
US20170042888A1 (en) 2017-02-16
JP6283766B2 (ja) 2018-02-21
AR100209A1 (es) 2016-09-21
MY189930A (en) 2022-03-22
KR101869185B1 (ko) 2018-06-19
PH12016501784B1 (en) 2016-11-07

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