MA33618B1 - Agent thérapeutique destiné aux troubles de l'humeur - Google Patents
Agent thérapeutique destiné aux troubles de l'humeurInfo
- Publication number
- MA33618B1 MA33618B1 MA34733A MA34733A MA33618B1 MA 33618 B1 MA33618 B1 MA 33618B1 MA 34733 A MA34733 A MA 34733A MA 34733 A MA34733 A MA 34733A MA 33618 B1 MA33618 B1 MA 33618B1
- Authority
- MA
- Morocco
- Prior art keywords
- mood disorders
- therapeutic agent
- therapeutic
- analog
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La présente invention concerne un agent thérapeutique et/ou prophylactique destiné aux troubles de l'humeur, qui contient un dérivé de thiazole représenté par la formule générale (i) dans laquelle r1 représente un groupe aryle ou analogue, et r2 représente un groupe pyridyle ou analogue) ou un de ses sels pharmaceutiquement acceptables en tant que principe actif.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009202893 | 2009-09-02 | ||
| PCT/JP2010/064988 WO2011027805A1 (fr) | 2009-09-02 | 2010-09-02 | Agent thérapeutique destiné aux troubles de l'humeur |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA33618B1 true MA33618B1 (fr) | 2012-09-01 |
Family
ID=43649339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA34733A MA33618B1 (fr) | 2009-09-02 | 2012-03-30 | Agent thérapeutique destiné aux troubles de l'humeur |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US9249135B2 (fr) |
| EP (1) | EP2474543B1 (fr) |
| JP (1) | JP5663484B2 (fr) |
| KR (1) | KR101762981B1 (fr) |
| CN (1) | CN102482272A (fr) |
| AU (1) | AU2010290423B2 (fr) |
| BR (1) | BR112012004851B8 (fr) |
| CA (1) | CA2772920C (fr) |
| CL (1) | CL2012000534A1 (fr) |
| CY (1) | CY1119118T1 (fr) |
| DK (1) | DK2474543T3 (fr) |
| DO (1) | DOP2012000058A (fr) |
| EA (1) | EA030333B1 (fr) |
| ES (1) | ES2633538T3 (fr) |
| GE (1) | GEP20156224B (fr) |
| HR (1) | HRP20171137T1 (fr) |
| HU (1) | HUE033690T2 (fr) |
| IL (1) | IL218321A (fr) |
| LT (1) | LT2474543T (fr) |
| MA (1) | MA33618B1 (fr) |
| ME (1) | ME02804B (fr) |
| MX (1) | MX2012002528A (fr) |
| NZ (1) | NZ598750A (fr) |
| PL (1) | PL2474543T3 (fr) |
| PT (1) | PT2474543T (fr) |
| RS (1) | RS56345B1 (fr) |
| SI (1) | SI2474543T1 (fr) |
| SM (1) | SMT201700359T1 (fr) |
| TN (1) | TN2012000092A1 (fr) |
| UA (1) | UA110097C2 (fr) |
| WO (1) | WO2011027805A1 (fr) |
| ZA (1) | ZA201202346B (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2551611C (fr) * | 2003-12-26 | 2013-06-25 | Kyowa Hakko Kogyo Co., Ltd. | Derive de thiazole pour le traitement ou la prevention de la maladie de parkinson |
| UA113383C2 (xx) * | 2009-09-02 | 2017-01-25 | Терапевтичний агент для лікування тривожних розладів | |
| MA41090A (fr) * | 2014-12-03 | 2017-10-10 | H Lundbeck As | Antagoniste de a2a faiblement dosé pour le traitement du tdah et de la maladie de parkinson |
| JOP20200093A1 (ar) | 2015-01-09 | 2017-06-16 | Kyowa Kirin Co Ltd | طريقة لإنتاج مشتق ثيازول |
| JO3544B1 (ar) * | 2015-03-19 | 2020-07-05 | Kyowa Kirin Co Ltd | عامل علاجي للاختلال الوظيفي في الفص الجبهي |
| TW201803869A (zh) | 2016-04-27 | 2018-02-01 | 健生藥品公司 | 作為ＲＯＲγＴ調節劑之６－胺基吡啶－３－基噻唑 |
| EP3807261B1 (fr) | 2018-06-18 | 2022-07-13 | Janssen Pharmaceutica NV | Pyridinyl-pyrazoles utilisés utilisés comme modulateurs de roryt |
| JP2021528405A (ja) | 2018-06-18 | 2021-10-21 | ヤンセン ファーマシューティカ エヌ．ベー． | ＲＯＲγｔのモジュレータとしてのアミド置換チアゾール |
| US11345666B2 (en) | 2018-06-18 | 2022-05-31 | Janssen Pharmaceutica Nv | Phenyl and pyridinyl substituted imidazoles as modulators of RORγT |
| EP3806958B1 (fr) | 2018-06-18 | 2022-09-07 | Janssen Pharmaceutica NV | 6-aminopyridin-3-yl pyrazoles en tant que modulateurs de roryt |
| WO2023201267A1 (fr) | 2022-04-13 | 2023-10-19 | Gilead Sciences, Inc. | Polythérapie pour le traitement de cancers exprimant trop-2 |
| WO2025137640A1 (fr) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Inhibiteurs azaspiro de wrn |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5543415A (en) | 1992-07-08 | 1996-08-06 | Kyowa Hakko Kogyo Co., Ltd. | Antidepressants |
| EP1016407B1 (fr) | 1997-09-05 | 2006-05-10 | Kyowa Hakko Kogyo Co., Ltd. | Derives de la xanthine contre l'ischemie cerebrale |
| WO2003022283A1 (fr) * | 2001-09-13 | 2003-03-20 | Schering Corporation | Combinaison d'un antagoniste du recepteur d'adenosine a2a et d'un antidepresseur ou d'un anxiolytique |
| US6620811B2 (en) | 2001-11-19 | 2003-09-16 | Hoffmann-La Roche Inc. | Isonicotin- and nicotinamide derivatives of benzothiazoles |
| KR20060037252A (ko) | 2003-06-10 | 2006-05-03 | 교와 핫꼬 고교 가부시끼가이샤 | 불안 장애의 치료 방법 |
| CA2551611C (fr) | 2003-12-26 | 2013-06-25 | Kyowa Hakko Kogyo Co., Ltd. | Derive de thiazole pour le traitement ou la prevention de la maladie de parkinson |
| CN101693695A (zh) | 2004-03-30 | 2010-04-14 | 大正制药株式会社 | 嘧啶衍生物以及与其应用有关的治疗方法 |
| EP1894930A4 (fr) * | 2005-06-23 | 2010-06-23 | Kyowa Hakko Kirin Co Ltd | Dérivé du thiazole |
| SI1921077T1 (sl) | 2005-08-02 | 2017-11-30 | Kyowa Hakko Kirin Co., Ltd. | Sredstvo za zdravljenje in/ali preprečevanje motnje spanja |
-
2010
- 2010-02-09 UA UAA201203928A patent/UA110097C2/uk unknown
- 2010-09-02 CA CA2772920A patent/CA2772920C/fr not_active Expired - Fee Related
- 2010-09-02 SM SM20170359T patent/SMT201700359T1/it unknown
- 2010-09-02 BR BR112012004851A patent/BR112012004851B8/pt not_active IP Right Cessation
- 2010-09-02 PL PL10813753T patent/PL2474543T3/pl unknown
- 2010-09-02 JP JP2011529926A patent/JP5663484B2/ja not_active Expired - Fee Related
- 2010-09-02 ME MEP-2017-168A patent/ME02804B/fr unknown
- 2010-09-02 WO PCT/JP2010/064988 patent/WO2011027805A1/fr not_active Ceased
- 2010-09-02 SI SI201031510T patent/SI2474543T1/sl unknown
- 2010-09-02 CN CN2010800392296A patent/CN102482272A/zh active Pending
- 2010-09-02 LT LTEP10813753.0T patent/LT2474543T/lt unknown
- 2010-09-02 DK DK10813753.0T patent/DK2474543T3/en active
- 2010-09-02 NZ NZ598750A patent/NZ598750A/en not_active IP Right Cessation
- 2010-09-02 HU HUE10813753A patent/HUE033690T2/hu unknown
- 2010-09-02 EA EA201270359A patent/EA030333B1/ru unknown
- 2010-09-02 AU AU2010290423A patent/AU2010290423B2/en not_active Ceased
- 2010-09-02 HR HRP20171137TT patent/HRP20171137T1/hr unknown
- 2010-09-02 KR KR1020127008307A patent/KR101762981B1/ko not_active Expired - Fee Related
- 2010-09-02 MX MX2012002528A patent/MX2012002528A/es active IP Right Grant
- 2010-09-02 GE GEAP201012647A patent/GEP20156224B/en unknown
- 2010-09-02 EP EP10813753.0A patent/EP2474543B1/fr active Active
- 2010-09-02 PT PT108137530T patent/PT2474543T/pt unknown
- 2010-09-02 ES ES10813753.0T patent/ES2633538T3/es active Active
- 2010-09-02 US US13/393,035 patent/US9249135B2/en not_active Expired - Fee Related
- 2010-09-02 RS RS20170748A patent/RS56345B1/sr unknown
-
2012
- 2012-02-26 IL IL218321A patent/IL218321A/en active IP Right Grant
- 2012-02-27 TN TNP2012000092A patent/TN2012000092A1/en unknown
- 2012-02-29 CL CL2012000534A patent/CL2012000534A1/es unknown
- 2012-03-01 DO DO2012000058A patent/DOP2012000058A/es unknown
- 2012-03-30 ZA ZA2012/02346A patent/ZA201202346B/en unknown
- 2012-03-30 MA MA34733A patent/MA33618B1/fr unknown
-
2017
- 2017-07-26 CY CY20171100798T patent/CY1119118T1/el unknown
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