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MA32563B1 - Dabigatran pour cathétérisme cardiaque de chirurgie percutanée - Google Patents

Dabigatran pour cathétérisme cardiaque de chirurgie percutanée

Info

Publication number
MA32563B1
MA32563B1 MA33616A MA33616A MA32563B1 MA 32563 B1 MA32563 B1 MA 32563B1 MA 33616 A MA33616 A MA 33616A MA 33616 A MA33616 A MA 33616A MA 32563 B1 MA32563 B1 MA 32563B1
Authority
MA
Morocco
Prior art keywords
dabigatran
percutaneous surgery
catheterism
cardiac
cardiac catheterism
Prior art date
Application number
MA33616A
Other languages
Arabic (ar)
English (en)
Inventor
Paul A Reilly
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41258283&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32563(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MA32563B1 publication Critical patent/MA32563B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La présente invention concerne une nouvelle utilisation du dabigatran étéxilate de formule (i) éventuellement sous la forme de ses sels pharmaceutiquement acceptables ainsi que de nouvelles formulations médicamenteuses pouvant être utilisées à cette fin.
MA33616A 2008-08-19 2011-02-15 Dabigatran pour cathétérisme cardiaque de chirurgie percutanée MA32563B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9001808P 2008-08-19 2008-08-19
PCT/EP2009/060592 WO2010020602A1 (fr) 2008-08-19 2009-08-17 Dabigatran pour cathétérisme cardiaque de chirurgie percutanée

Publications (1)

Publication Number Publication Date
MA32563B1 true MA32563B1 (fr) 2011-08-01

Family

ID=41258283

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33616A MA32563B1 (fr) 2008-08-19 2011-02-15 Dabigatran pour cathétérisme cardiaque de chirurgie percutanée

Country Status (19)

Country Link
US (1) US20110301201A1 (fr)
EP (1) EP2328580A1 (fr)
JP (1) JP2012500245A (fr)
KR (1) KR20110044230A (fr)
CN (1) CN102123707A (fr)
AR (1) AR073077A1 (fr)
AU (1) AU2009284217A1 (fr)
BR (1) BRPI0917507A2 (fr)
CA (1) CA2734794A1 (fr)
CL (1) CL2011000361A1 (fr)
CO (1) CO6290686A2 (fr)
EA (1) EA201100358A1 (fr)
EC (1) ECSP11010825A (fr)
IL (1) IL210005A0 (fr)
MA (1) MA32563B1 (fr)
MX (1) MX2011001612A (fr)
NZ (1) NZ591108A (fr)
TW (1) TW201022235A (fr)
WO (1) WO2010020602A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR074313A1 (es) 2008-11-11 2011-01-05 Boehringer Ingelheim Int Metodo para tratar o prevenir la trombosis utilizando etexilato de dabigatran o una sal del mismo. uso. kit
EA201201202A1 (ru) * 2010-03-01 2013-04-30 Рациофарм Гмбх Пероральная фармацевтическая композиция, содержащая этексилат дабигатрана
RU2017144535A (ru) 2010-03-30 2019-02-18 Версеон Корпорейшн Мультизамещенные ароматические соединения в качестве ингибиторов тромбина
CN102391250B (zh) * 2011-08-29 2013-06-19 石药集团欧意药业有限公司 一种达比加群酯化合物、制备方法及其药物组合物
CN102558153A (zh) * 2012-02-08 2012-07-11 北京阜康仁生物制药科技有限公司 达比加群酯的新药用盐及其制备方法
CN103420982B (zh) * 2012-05-24 2015-07-08 天津药物研究院 达比加群酯衍生物及其制备方法和用途
CN103420994B (zh) * 2012-05-24 2016-04-06 天津药物研究院 作为前药的达比加群酯衍生物及其制备方法和用途
CN103420985B (zh) * 2012-05-24 2015-09-23 天津药物研究院 作为前药的达比加群酯衍生物及其制备方法和用途
CN103420984B (zh) * 2012-05-24 2015-07-08 天津药物研究院 作为前药的达比加群酯衍生物及其制备方法和用途
CN103524559B (zh) * 2012-07-05 2016-09-28 西藏海思科药业集团股份有限公司 多取代4-甲氨基苯甲脒的酯衍生物及其制备方法和用途
CN103539779B (zh) * 2012-07-13 2016-12-21 四川海思科制药有限公司 一种达比加群酯的羟基取代苯磺酸盐及其制备方法和用途
US20150225370A1 (en) * 2012-09-28 2015-08-13 Ranbaxy Laboratories Limited Process for the preparation of dabigatran etexilate or pharmaceutically acceptable salt thereof
US9399616B2 (en) 2012-10-22 2016-07-26 Boehringer Ingelheim International Gmbh Process for the manufacture of 4-aminobenzoamidine dihydrochloride
PL2968297T3 (pl) 2013-03-15 2019-04-30 Verseon Corp Wielopodstawione związki aromatyczne jako inhibitory protezy serynowej
BR112015023214A8 (pt) 2013-03-15 2019-12-24 Verseon Corp composto, composição farmacêutica, e, uso de um composto ou composição farmacêutica
EP3194369A4 (fr) 2014-09-17 2018-02-28 Verseon Corporation Composés de pyridone substituée par pyrazolyl en tant qu'inhibiteurs de sérine protéase
CA2977993A1 (fr) 2015-02-27 2016-09-01 Verseon Corporation Composes pyrazole substitues a utiliser en tant qu'inhibiteurs de serine protease
WO2020014669A1 (fr) 2018-07-13 2020-01-16 Verseon Corporation Inhibiteurs de la thrombine, formulations et utilisations associées

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1485094T4 (da) * 2002-03-07 2020-06-22 Boehringer Ingelheim Int Doseringsform til oral indgivelse af 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1h-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsyre-ethylester eller dets salte
CA2587026A1 (fr) * 2004-10-25 2006-05-04 Boehringer Ingelheim International Gmbh Utilisation de dipyridamole en association avec des antithrombotiques pour traiter et prevenir des maladies thromboemboliques
CA2657270A1 (fr) * 2006-07-17 2008-01-24 Boehringer Ingelheim International Gmbh Nouvelles indications pediatriques pour des inhibiteurs directs de la thrombine
BRPI0715492A2 (pt) * 2006-07-17 2013-03-19 Boehringer Ingelheim Int uso de inibidores diretos de trombina
US20100087488A1 (en) * 2006-10-10 2010-04-08 Boehringer Ingelheim International Gmgh Physiologically Acceptable Salts of 3-[(2--1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester

Also Published As

Publication number Publication date
CA2734794A1 (fr) 2010-02-25
AU2009284217A1 (en) 2010-02-25
TW201022235A (en) 2010-06-16
KR20110044230A (ko) 2011-04-28
MX2011001612A (es) 2011-03-04
US20110301201A1 (en) 2011-12-08
CO6290686A2 (es) 2011-06-20
BRPI0917507A2 (pt) 2015-11-17
JP2012500245A (ja) 2012-01-05
EP2328580A1 (fr) 2011-06-08
NZ591108A (en) 2012-11-30
CL2011000361A1 (es) 2011-06-17
AR073077A1 (es) 2010-10-13
ECSP11010825A (es) 2011-03-31
CN102123707A (zh) 2011-07-13
WO2010020602A1 (fr) 2010-02-25
IL210005A0 (en) 2011-02-28
EA201100358A1 (ru) 2011-10-31

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