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MA30037B1 - Compositions et procedes destines au traitement des troubles du snc - Google Patents

Compositions et procedes destines au traitement des troubles du snc

Info

Publication number
MA30037B1
MA30037B1 MA31013A MA31013A MA30037B1 MA 30037 B1 MA30037 B1 MA 30037B1 MA 31013 A MA31013 A MA 31013A MA 31013 A MA31013 A MA 31013A MA 30037 B1 MA30037 B1 MA 30037B1
Authority
MA
Morocco
Prior art keywords
treatment
compositions
methods
cns disorders
thienopyridinone
Prior art date
Application number
MA31013A
Other languages
English (en)
Inventor
Dale S Dhanoa
Oren M Becker
Silvia Noiman
Pradyumna Mohanty
Dongli Chen
Mercedes Lobera
Laurence Wu
Yael Marantz
Boaz Inbal
Alexander Heifetz
Shay Bar-Haim
Sharon Shacham
Original Assignee
Epix Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epix Pharm Inc filed Critical Epix Pharm Inc
Publication of MA30037B1 publication Critical patent/MA30037B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne d'une manière générale des modulateurs du récepteur de la thiénopyridinone 5-HT4 et en particulier l'utilisation de ces composés et de leurs compositions pharmaceutiques, par exemple pour le traitement, la modulation et/ou la prévention d'états physiologiques associés à l'action de la sérotonine tels que la maladie d'Alzheimer, les troubles de la cognition, la dépression et l'anxiété.
MA31013A 2005-11-10 2008-06-06 Compositions et procedes destines au traitement des troubles du snc MA30037B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/271,019 US7598265B2 (en) 2004-09-30 2005-11-10 Compositions and methods for treating CNS disorders

Publications (1)

Publication Number Publication Date
MA30037B1 true MA30037B1 (fr) 2008-12-01

Family

ID=37946751

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31013A MA30037B1 (fr) 2005-11-10 2008-06-06 Compositions et procedes destines au traitement des troubles du snc

Country Status (17)

Country Link
US (2) US7598265B2 (fr)
EP (1) EP1959954A2 (fr)
JP (1) JP2009515877A (fr)
KR (1) KR20080067001A (fr)
CN (1) CN101340908A (fr)
AR (1) AR057887A1 (fr)
AU (1) AU2006315854A1 (fr)
BR (1) BRPI0618493A2 (fr)
CA (1) CA2629312C (fr)
CR (1) CR10062A (fr)
EA (1) EA200801302A1 (fr)
IL (1) IL191168A0 (fr)
MA (1) MA30037B1 (fr)
NO (1) NO20082679L (fr)
TW (1) TW200735868A (fr)
WO (1) WO2007058805A2 (fr)
ZA (1) ZA200804951B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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US7612078B2 (en) * 2003-03-31 2009-11-03 Epix Delaware, Inc. Piperidinylamino-thieno[2,3-D] pyrimidine compounds
US20050222175A1 (en) * 2004-03-31 2005-10-06 Dhanoa Dale S New piperidinylamino-thieno[2,3-D] pyrimidine compounds
US7488736B2 (en) * 2004-05-17 2009-02-10 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7407966B2 (en) * 2004-10-07 2008-08-05 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7598265B2 (en) * 2004-09-30 2009-10-06 Epix Delaware, Inc. Compositions and methods for treating CNS disorders
US7576211B2 (en) * 2004-09-30 2009-08-18 Epix Delaware, Inc. Synthesis of thienopyridinone compounds and related intermediates
JP5186219B2 (ja) 2005-01-25 2013-04-17 エピックス デラウェア， インコーポレイテッド 置換アリールアミン化合物および５−ｈｔ６調節因子としてのその使用
GB0526258D0 (en) * 2005-12-22 2006-02-01 Novartis Ag Organic compounds
EP2445877B1 (fr) * 2008-12-03 2014-07-23 Nanotherapeutics, Inc. Composés bicycliques et leurs procédés de fabrication et d'utilisation
MX2011010782A (es) * 2009-04-13 2012-01-20 Theravance Inc Compuestos agonistas del receptor 5-ht4 para el tratamiento de trastornos cognitivos.
WO2022169973A1 (fr) * 2021-02-04 2022-08-11 Natrillo Richard Complément alimentaire pour améliorer les performances cérébrales

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Also Published As

Publication number Publication date
EA200801302A1 (ru) 2009-02-27
AU2006315854A1 (en) 2007-05-24
CA2629312A1 (fr) 2007-05-24
ZA200804951B (en) 2009-04-29
WO2007058805A2 (fr) 2007-05-24
EP1959954A2 (fr) 2008-08-27
CR10062A (es) 2009-05-14
CN101340908A (zh) 2009-01-07
US20110195953A1 (en) 2011-08-11
TW200735868A (en) 2007-10-01
US7598265B2 (en) 2009-10-06
BRPI0618493A2 (pt) 2011-08-30
US20060234998A1 (en) 2006-10-19
NO20082679L (no) 2008-06-10
IL191168A0 (en) 2008-12-29
JP2009515877A (ja) 2009-04-16
AR057887A1 (es) 2007-12-26
KR20080067001A (ko) 2008-07-17
WO2007058805A3 (fr) 2007-10-04
CA2629312C (fr) 2014-08-12

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