[go: up one dir, main page]

MA27195A1 - Derives d'acyl-3 -carboxyphenyluree, procedes pour les preparer et leur utilisation. - Google Patents

Derives d'acyl-3 -carboxyphenyluree, procedes pour les preparer et leur utilisation.

Info

Publication number
MA27195A1
MA27195A1 MA27903A MA27903A MA27195A1 MA 27195 A1 MA27195 A1 MA 27195A1 MA 27903 A MA27903 A MA 27903A MA 27903 A MA27903 A MA 27903A MA 27195 A1 MA27195 A1 MA 27195A1
Authority
MA
Morocco
Prior art keywords
acyl
preparation
processes
derivatives
carboxyphenylurea
Prior art date
Application number
MA27903A
Other languages
English (en)
Inventor
Elisabeth Defossa
Dieter Kadereit
Karl Schoenafinger
Thomas Klabunde
Hans-Joerg Burger
Andreas Herling
Karl-Ulrich Wendt
Roedern Erich Von
Alfons Enhsen
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of MA27195A1 publication Critical patent/MA27195A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/48—Y being a hydrogen or a carbon atom
    • C07C275/54—Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Dérivés d'acyl-3-carboxyphénylurée, procédés pour les préparer et leur utilisation. L'invention concerne des dérivés d'acyl-3-carboxyphénylurée ainsi que leurs sels tolérés physiologiquement et dérivés physiologiquement fonctionnels. L'invention concerne les composés de formule (I) dans laquelle les restes ont les significations indiquées, ainsi que leurs sels tolérés physiologiquement et procédé pour leur préparation. Les composés conviennent, par exemple, en tant qu'antidiabétiques.
MA27903A 2002-04-11 2004-10-08 Derives d'acyl-3 -carboxyphenyluree, procedes pour les preparer et leur utilisation. MA27195A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10215908A DE10215908B4 (de) 2002-04-11 2002-04-11 Acyl-3-carboxyphenyl-harnstoffderivate und deren Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
MA27195A1 true MA27195A1 (fr) 2005-01-03

Family

ID=28684936

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27903A MA27195A1 (fr) 2002-04-11 2004-10-08 Derives d'acyl-3 -carboxyphenyluree, procedes pour les preparer et leur utilisation.

Country Status (23)

Country Link
EP (1) EP1497263B1 (fr)
JP (1) JP4328212B2 (fr)
KR (1) KR20040097332A (fr)
CN (1) CN1263734C (fr)
AR (1) AR039402A1 (fr)
AT (1) ATE404532T1 (fr)
AU (1) AU2003232192A1 (fr)
BR (1) BR0309130A (fr)
CA (1) CA2481819A1 (fr)
DE (2) DE10215908B4 (fr)
HR (1) HRP20040931A2 (fr)
HU (1) HUP0500203A2 (fr)
IL (1) IL164248A0 (fr)
MA (1) MA27195A1 (fr)
MX (1) MXPA04009239A (fr)
NO (1) NO20044881L (fr)
NZ (1) NZ535833A (fr)
PL (1) PL371317A1 (fr)
RS (1) RS88704A (fr)
RU (1) RU2004133046A (fr)
TW (1) TW200401765A (fr)
WO (1) WO2003084923A1 (fr)
ZA (1) ZA200407361B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL164249A0 (en) * 2002-04-11 2005-12-18 Aventis Pharma Gmbh Acyl-3-carboxphenylurea derivatives, processes forpreparing them and their use
DE10306502B4 (de) * 2003-02-17 2005-03-17 Aventis Pharma Deutschland Gmbh Substituierte 3-(Benzoylureido)-thiophenderivate und sie enthaltende Arzneimittel
DE10308352A1 (de) 2003-02-27 2004-09-09 Aventis Pharma Deutschland Gmbh Arylcycloalkylderivate mit verzweigten Seitenketten, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
US7148246B2 (en) 2003-02-27 2006-12-12 Sanofi-Aventis Deutschland Gmbh Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
DE10308355A1 (de) 2003-02-27 2004-12-23 Aventis Pharma Deutschland Gmbh Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
DE10308351A1 (de) 2003-02-27 2004-11-25 Aventis Pharma Deutschland Gmbh 1,3-substituierte Cycloalkylderivate mit sauren, meist heterocyclischen Gruppen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10308353A1 (de) 2003-02-27 2004-12-02 Aventis Pharma Deutschland Gmbh Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US7241787B2 (en) 2004-01-25 2007-07-10 Sanofi-Aventis Deutschland Gmbh Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments
DE602004004631D1 (de) 2004-04-01 2007-03-22 Sanofi Aventis Deutschland Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika
DE102005026762A1 (de) 2005-06-09 2006-12-21 Sanofi-Aventis Deutschland Gmbh Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA867420B (en) * 1985-09-30 1987-05-27 Union Carbide Corp Pesticidal 1-(4-aryloxyphenyl)-3-benzoyl urea compounds and process for preparation
GB9313268D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Chemical compounds
AP624A (en) * 1995-06-06 1997-12-19 Pfizer Substituted n-(indole-2-carbonyl)-b- alanimamides and derivatives as antidiabetic agents.
WO2000056707A1 (fr) * 1999-03-24 2000-09-28 Sepracor, Inc. Thioethers de diaryle, compositions et utilisations de ces dernieres
AR028253A1 (es) * 2000-03-16 2003-04-30 Pfizer Prod Inc Inhibidores de la glucogeno fosforilasa
AU2001262318B2 (en) * 2000-06-09 2005-09-08 Sanofi-Aventis Deutschland Gmbh Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament
GB0021831D0 (en) * 2000-09-06 2000-10-18 Astrazeneca Ab Chemical compounds
PE20021091A1 (es) * 2001-05-25 2003-02-04 Aventis Pharma Gmbh Derivados de fenilurea sustituidos con carbonamida y procedimiento para su preparacion

Also Published As

Publication number Publication date
MXPA04009239A (es) 2005-01-25
JP4328212B2 (ja) 2009-09-09
JP2005522481A (ja) 2005-07-28
AR039402A1 (es) 2005-02-16
DE10215908A1 (de) 2003-11-06
DE50310320D1 (de) 2008-09-25
EP1497263A1 (fr) 2005-01-19
HUP0500203A2 (hu) 2005-06-28
NZ535833A (en) 2006-03-31
DE10215908B4 (de) 2005-08-18
CN1263734C (zh) 2006-07-12
NO20044881L (no) 2005-01-07
IL164248A0 (en) 2005-12-18
CN1646486A (zh) 2005-07-27
AU2003232192A1 (en) 2003-10-20
BR0309130A (pt) 2005-02-01
PL371317A1 (en) 2005-06-13
ATE404532T1 (de) 2008-08-15
RS88704A (sr) 2007-02-05
EP1497263B1 (fr) 2008-08-13
HK1075650A1 (en) 2005-12-23
KR20040097332A (ko) 2004-11-17
WO2003084923A1 (fr) 2003-10-16
RU2004133046A (ru) 2005-04-20
HRP20040931A2 (en) 2005-02-28
ZA200407361B (en) 2006-02-22
CA2481819A1 (fr) 2003-10-16
TW200401765A (en) 2004-02-01

Similar Documents

Publication Publication Date Title
MA27559A1 (fr) Nouveaux derives de fluorglycoside aromatiques, produits pharmaceutiques contenant ces composes et leur utilisation
MA27560A1 (fr) Nouveaux derives de fluorglycoside heterocycliques, produits pharmaceutiques contenant ces composes et leur utilisation
MA26723A1 (fr) Acides oxamiques nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
MA27774A1 (fr) Inhibiteurs de phosphatidylinositol 3-kinase
TNSN01028A1 (fr) Derives de purine nouveaux, procede pour leur preparation et compositions les contenant
MA26697A1 (fr) Composes nouveaux inhibiteurs de gsk-3 et compositions pharmaceutiques les contenant
MA24729A1 (fr) Macrolides nouveaux.
MA29926B1 (fr) Derives de pyrazine
TNSN98082A1 (fr) DERIVES SUBSTITUES EN C - 4 DE 9 - DESOXO - 9a - aza - 9a HOMOERYTHROMYCINE A.
TNSN07022A1 (fr) Derives de pyridine
MA27427A1 (fr) Composes de benzimidazole-1-yl-thiophene utilises en cancerotherapie
MA31586B1 (fr) Dérivés d'alcools alkyliques de 1-phényl-2-pyridinyle en tant qu'inhibiteurs de la phosphodiestérase
TNSN05073A1 (fr) Quinazolinones spirocondensees nouvelles et leur utilisation comme inhibiteurs de phosphodiesterase
MA31894B1 (fr) Composes organiques
MA30911B1 (fr) Nouveaux derives de sulfonamide en tant qu'antagonistes de bradykinine
TNSN00203A1 (fr) Derives de purine nouveaux, procede pour leur preparation et des compositions les contenant
FR2708605A1 (fr) Dérivés du N-sulfonylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant.
TNSN99106A1 (fr) Derives d'isothiazole nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2382441A1 (fr) Nouveaux n-(aminoalkyl substitue)-2-oxo-1-pyrrolidine-acetamides utiles en tant que medicaments et procedes pour leur preparation
TN2009000450A1 (fr) Derives de pyridine
FR2708608A1 (fr) Dérivés de N-sulfonylbenzimidazolone, leur préparation, les compositions pharmaceutiques en contenant.
MA27883A1 (fr) Derives de pyrido [2,1-a] isoquinoline utilises comme inhibiteurs de dpp-iv
TNSN97110A1 (fr) Derives de 2-(2-oxo-ethylidene)-imidazolidine-4-one, procede pour leur preparation et compositions pharmaceutiques les contenant
TNSN01077A1 (fr) Derives de tropane nouveaux, procede pour leur preparation et compositions les contenant
MA27769A1 (fr) Dérivées de 2-acylamino-4-phenylthiazole, leur préparation et leur application en thérapeutique