Samarasinghe et al., 2021 - Google Patents
Comparison of separation modes for microchip electrophoresis of proteinsSamarasinghe et al., 2021
View PDF- Document ID
- 3637564610612977058
- Author
- Samarasinghe T
- Zeng Y
- Johnson C
- Publication year
- Publication venue
- Journal of separation science
External Links
Snippet
Separation of a set of model proteins was tested on a microchip electrophoresis analytical platform capable of sample injection by two different electrokinetic mechanisms. A range of separation modes—microchip capillary zone electrophoresis, microchip micellar …
- 238000000926 separation method 0 title abstract description 101
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44743—Introducing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44747—Composition of gel or of carrier mixture
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44752—Controlling the zeta potential, e.g. by wall coatings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44791—Micro-apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/558—Immunoassay; Biospecific binding assay using diffusion or migration of antigen or antibody
- G01N33/561—Immunoelectrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Herr et al. | On-chip coupling of isoelectric focusing and free solution electrophoresis for multidimensional separations | |
| Krebs et al. | Strategies for capillary electrophoresis: method development and validation for pharmaceutical and biological applications—updated and completely revised edition | |
| Li | Capillary electrophoresis: principles, practice and applications | |
| Ramos‐Payán et al. | Recent trends in capillary electrophoresis for complex samples analysis: a review | |
| von Heeren et al. | Micellar electrokinetic chromatography separations and analyses of biological samples on a cyclic planar microstructure | |
| Li et al. | Integration of isoelectric focusing with parallel sodium dodecyl sulfate gel electrophoresis for multidimensional protein separations in a plastic microfludic network | |
| US8241476B1 (en) | Sol-gel coatings for on-line preconcentration in capillary electrophoresis | |
| Fu et al. | Sample preconcentration from dilute solutions on micro/nanofluidic platforms: A review | |
| Štěpánová et al. | Analysis of proteins and peptides by electromigration methods in microchips | |
| Dadoo et al. | Advances in capillary electrochromatography: Rapid and high-efficiency separations of PAHs | |
| Tran et al. | Recent innovations in protein separation on microchips by electrophoretic methods: an update | |
| US6998040B2 (en) | Sol-gel open tubular ODS columns with charged inner surface for capillary electrochromatography | |
| Tagliaro et al. | Capillary electrophoresis: principles and applications in illicit drug analysis | |
| Krull et al. | Specific applications of capillary electrochromatography to biopolymers, including proteins, nucleic acids, peptide mapping, antibodies, and so forth | |
| Gencoglu et al. | Quantification of pH gradients and implications in insulator‐based dielectrophoresis of biomolecules | |
| US20090071828A1 (en) | Devices Exhibiting Differential Resistance to Flow and Methods of Their Use | |
| Iki et al. | Electrostatic and hydrodynamic separation of DNA fragments in capillary tubes | |
| Wang et al. | Exceeding 20 000‐fold concentration of protein by the on‐line isotachophoresis concentration in poly (methyl methacrylate) microchip | |
| Samarasinghe et al. | Comparison of separation modes for microchip electrophoresis of proteins | |
| Wang et al. | Integration of capillary isoelectric focusing with monolithic immobilized pH gradient, immobilized trypsin microreactor and capillary zone electrophoresis for on‐line protein analysis | |
| CA2686254A1 (en) | System and method for proteomics | |
| Roman et al. | Micellar electrokinetic chromatography of fluorescently labeled proteins on poly (dimethylsiloxane)‐based microchips | |
| EP1129345A1 (en) | Practical device for controlling ultrasmall volume flow | |
| Liu et al. | Hydrogels in electrophoresis: applications and advances | |
| Shaabani et al. | Size‐based proteins separation using polymer‐entrapped colloidal self‐assembled nanoparticles on‐chip |