Stoltz et al., 1998 - Google Patents
The CYP2B2 phenobarbital response unit contains an accessory factor element and a putative glucocorticoid response element essential for conferring maximal …Stoltz et al., 1998
View HTML- Document ID
- 306044730071669616
- Author
- Stoltz C
- Vachon M
- Trottier E
- Dubois S
- Paquet Y
- Anderson A
- Publication year
- Publication venue
- Journal of Biological Chemistry
External Links
Snippet
Hepatic cytochrome P450s play a critical role in the metabolism of hydrophobic xenobiotics. One of the major unsolved problems in xenobiotic metabolism is the molecular mechanism whereby phenobarbital induces hepatic enzymes, particularly CYP2B1 and CYP2B2 in rat …
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