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Martiszus et al., 2021 - Google Patents

Enhanced excitability of cortical neurons in low-divalent solutions is primarily mediated by altered voltage-dependence of voltage-gated sodium channels

Martiszus et al., 2021

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Document ID
3067052664594600703
Author
Martiszus B
Tsintsadze T
Chang W
Smith S
Publication year
Publication venue
Elife

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Increasing extracellular [Ca2+]([Ca2+] o) strongly decreases intrinsic excitability in neurons but the mechanism is unclear. By one hypothesis,[Ca2+] o screens surface charge, reducing voltage-gated sodium channel (VGSC) activation and by another [Ca2+] o activates Calcium …
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