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Kim et al., 2018 - Google Patents

Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing

Kim et al., 2018

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Document ID
2166070065336736447
Author
Kim J
Dilthey A
Nagaraja R
Lee H
Koren S
Dudekula D
Wood III W
Piao Y
Ogurtsov A
Utani K
Noskov V
Shabalina S
Schlessinger D
Phillippy A
Larionov V
Publication year
Publication venue
Nucleic acids research

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Despite the key role of the human ribosome in protein biosynthesis, little is known about the extent of sequence variation in ribosomal DNA (rDNA) or its pre-rRNA and rRNA products. We recovered ribosomal DNA segments from a single human chromosome 21 using …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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